Guest house holiday rentals in San Diego

Find and book unique guest house rentals on Airbnb

0 of 0 items showing
1 of 3 pages

Popular amenities for guest house rentals in San Diego

Family-friendly guest house rentals

Top guest favourite
Guest house in Talmadge
4.98 out of 5 average rating, 209 reviews

Lovely Guesthouse in garden setting

RamonaRating, 5 stars6 months ago
We are so grateful to have been able to stay at Gwynn's place, it is so peaceful and lovely. Like a secret garden getaway. We loved all the small touches, and beauty of the space. Gwynn made us feel very welcome and comfortable! The pool is amazing and the outdoor spaces are delightful. Can't wait to stay here again.
Top guest favourite
Guest house in Hillcrest
4.98 out of 5 average rating, 166 reviews

Hidden Casita with Private Deck & Patio

SamanthaRating, 5 stars3 weeks ago
We had such a lovely time at Jane's casita. It was so quiet, walkable to everything, and peaceful. Lots of birds to be seen from the patio. I'm glad we stayed here for our San Diego vacation and would definitely stay here again! Cute decor, too :)
Guest favourite
Guest house in Mission Hills
4.92 out of 5 average rating, 423 reviews

La Casita - Fully Updated Casita in Mission Hills

MollyRating, 5 stars2 days ago
The casita was perfect for one or two guests, intimate space but did the job. It was very clean, in a nice and quiet neighborhood. We took a walk one of the mornings to a nearby coffee shop which was very peaceful and enjoyable. The location is a short drive to downtown and the beach which was very convenient. I would stay here again.
Top guest favourite
Guest house in La Mesa
4.99 out of 5 average rating, 279 reviews

Spacious, private Mt. Helix country style studio

RhondaRating, 5 stars1 month ago
Absolutely worth it. Beautiful place. Cozy with gorgeous gardens. Also a nice welcome touch of bowl of fruits, chocolates and plenty to drink. Loved it.
Top guest favourite
Guest house in Greater North Park
4.97 out of 5 average rating, 186 reviews

New Guest House - North Park

KrystenRating, 5 stars3 weeks ago
Lynae’s place was wonderful, as was Lynae! Balboa park right nearby, with gorgeous trails and scenery. Walkable to North Park area which had a fun variety of bars, shops, and restaurants. Lynae was a wonderful host - responsive, kind, flexible - and the home was bright, airy, with gorgeous views. We couldn’t say enough good things about the wall of jasmine walking in. Thank you Lynae for having us in your home!
Top guest favourite
Guest house in Sherman Heights
4.96 out of 5 average rating, 533 reviews

Romantic Private Garden Studio Near Downtown

HéctorRating, 5 stars3 weeks ago
Kathi and Byron are great hosts and the place is beautiful, exactly as described. We had a great time, the place is very close to everything, there is a liquor store just 1 block away, very comfortable bed, beautiful garden 😃😃😃😃 Thank you very much Kathi, we hope to come back soon to San Diego and we will definitely book your place again.
Top guest favourite
Guest house in University City
4.92 out of 5 average rating, 451 reviews

Garden Cottage | 200Mbps | Sofabed | 55”TV | Patio

LeslieRating, 5 stars1 week ago
We had a great stay, the cottage was so cozy and felt right at home. The garden outside of the cottage was absolutely beautiful. Thank you again Donna for hosting us!
Guest favourite
Guest house in Kensington
4.97 out of 5 average rating, 582 reviews

Central & Serene Secret Garden Guesthouse

JenniferRating, 5 stars2 weeks ago
We loved Susie’s garden guesthouse! Very walkable to a lot of lovely restaurants and close to SDSU!

Guest house rentals with a patio

Top guest favourite
Guest house in Kit Carson
4.99 out of 5 average rating, 135 reviews

Garden Casita

PhilippaRating, 5 stars1 week ago
Charming, peaceful, spotlessly clean and exceptionally well appointed. We were in town for a wedding and this was the perfect location. Close to everything you could possibly need, located in a delightful, quiet neighborhood. Lovely outdoor area with barbecue and our personal favorite was the balcony with fire pit which was perfect for relaxing with a drink after dinner. Pete was friendly, responsive and clearly pays great attention to detail as there were so many special touches. We had a wonderful stay made even better with the sweetest “greeter” Rudy the dog. I highly recommend staying here.
Top guest favourite
Guest house in La Mesa
4.99 out of 5 average rating, 115 reviews

Private 1 BR Paradise retreat

AlleshaRating, 5 stars1 week ago
Jeanne and John's place was exactly as advertised in the description and photographs. The backyard and pool were beautiful unfortunately the weather and our schedule of events did not permit us time to indulge. If we ever needed a place in the area again we would definitely reserve another stay. We felt so welcomed and the extras were so thoughtful...like a balloon for my husband's birthday and a handwritten welcome letter. Thank you for the hospitality!
Guest favourite
Guest house in Chula Vista
4.94 out of 5 average rating, 145 reviews

New! Beautiful Private Casita- King Bed & Office

OscarRating, 5 stars3 weeks ago
My wife and I had a wonderful stay. Place was clean, host was responsive to any questions, the bed was comfortable, and it was close to many tourist locations. Would definitely recommend!
Guest favourite
Guest house in Serra Mesa
4.95 out of 5 average rating, 105 reviews

Cozy, Quiet and Private Backyard Studio Escape

JoeeRating, 5 stars1 week ago
I had an absolutely wonderful stay at Stephanie's place! The space was spotless and made me feel right at home. The location was fantastic and the check-in process was incredibly easy. Stephanie was an outstanding host, always quick to respond to any questions. I especially loved the rain shower! I highly recommend this Airbnb to anyone visiting San Diego and would definitely love to stay here again!
Superhost
Guest house in City Heights
4.86 out of 5 average rating, 265 reviews

Heart of SD | Zoo Nearby | Private Patio | Central

LaylaRating, 5 stars5 days ago
This is a nice little private spot you can be at right by Balboa Park. Close to Downtown, and the host was great and very responsive. I believe the washer and dryer is a plus! One thing I loved is Hulu is set up on the TV so that was really nice!
Top guest favourite
Guest house in Greater North Park
4.98 out of 5 average rating, 125 reviews

New (2022) North Park Abode w/ Roof Deck

KimRating, 5 stars1 month ago
A fantastic location in North Park near Balboa Park with gorgeous views from the 2nd floor deck. It made for a gorgeous backdrop for graduation family photos! There are ample nearby restaurant choices for this safe and quiet neighborhood. Comes with a very comfortable bed, and a variety of pillows with an efficient kitchenette.. only wish the shower head streamed more water. Hosts were very gracious and responsive to our requests. I definitly plan to stay here again and have already recommended this awesome place to friends.
Superhost
Guest house in National City
4.85 out of 5 average rating, 154 reviews

Private Pet-Friendly Studio w/Parking Near Gaslamp

DanielRating, 5 stars2 days ago
The place was ADORABLE and you could tell there was a women’s touch, my wife LOVED IT! Omar was very open to pets, our pup Beast was extremely comfy. We had a small issue with the lock but Omar had it fixed in a matter of minutes and anytime I reached out he replied immediately. The neighborhood was National City which isn’t La Jolla. The unit is next to a church so there were “choir nights” which would have been nice to know. Other than that very clean, very roomy with a full kitchen. There is no washer/dryer so an extended stay will be challenging but we managed. We would absolutely stay here again in the future! THANK YOU AGAIN OMAR!!
Guest favourite
Guest house in La Mesa
4.95 out of 5 average rating, 325 reviews

La Mesa Suite

KeanaRating, 5 stars1 month ago
Wonderful place to stay with private space in a quiet and safe neighborhood. Lots of restaurants and places to visit close by.

Guest house rentals with a washing machine and dryer

Top guest favourite
Guest house in La Mesa
4.99 out of 5 average rating, 188 reviews

Stunning Guest House 15 min. from Zoo, Downtown

MarkRating, 5 stars1 week ago
Lynn's place was just what we were looking for. Lynn is very friendly and helpful. I can't recommend it more!
Guest favourite
Guest house in City Heights
4.98 out of 5 average rating, 135 reviews

Private Guest House for 2 with Kitchen + Laundry

ArleneRating, 5 stars1 month ago
The place was exactly as described! Paid for a place with far less amenities for the exact same price range so definitely recommend this one!
Guest favourite
Guest house in Mission Beach
4.9 out of 5 average rating, 734 reviews

South Mission Beach Zen-Like Studio

MyaRating, 5 stars2 weeks ago
Truly looks better than the photos! Was a great place to stay and right on the beach!
Top guest favourite
Guest house in Rancho Santa Fe
4.99 out of 5 average rating, 166 reviews

Rancho Relaxo / Spacious Detached Guest House

JaneRating, 5 stars3 weeks ago
my daughter and I stayed at Susie and Britt's poolhouse for 6 nights when we were in the San Diego area for a wedding. At first we thought we would look for a beach rental but then heard that it can be foggy on the coast during May and June and going 5 miles inland can make a big difference with weather. we looked in Rancho Sante Fe because that we where the wedding venue was located and we really hit the jackpot! Everything is just as described- very relaxing times in the jacuzzi and by the fire pit in the evenings. The travel to the surrounding SanDiego sights was super easy. Highly recommend this rental!!!
Top guest favourite
Guest house in El Cajon
4.98 out of 5 average rating, 222 reviews

Fletcher Hills - modern 1 BR.Easy, no step access.

LaurissaRating, 5 stars1 week ago
We had a fabulous time at the Granny Flat! Everything was pristine and Kristen has thought of every amenity. She was kind and responsive. We loved the peaceful backyard with gorgeous views. The location is super convenient and a max of 25-30 mins to anywhere else in the SD area. Our pups had a great time, too! Would love to stay here again!
Guest favourite
Guest house in Cherokee Point
4.95 out of 5 average rating, 150 reviews

Cozy Cottage 1/2 mile to North Park close to dtwn

JasonRating, 5 stars2 weeks ago
Excellent place. We loved the location relative to the sites we wanted to see. Free parking, laundry, very well stocked kitchen, comfortable bed. We were very comfortable and happy here. And as a host Wendy was phenomenal. One of the most responsive hosts I’ve had the pleasure of connecting with on Airbnb. Thank you Wendy!!!
Superhost
Guest house in Ocean Beach
4.89 out of 5 average rating, 329 reviews

Indoor/Outdoor Sanctuary in Ocean Beach

AnthonyRating, 5 stars6 days ago
We had a great stay at Lori’s place. Very private from the other property. The backyard was perfect for winding down and enjoying your own space for dinner. Location is perfect in OB. We would come back!
Guest favourite
Guest house in Mission Beach
4.88 out of 5 average rating, 346 reviews

Rockaway North - Family Friendly, Garage Parking & Laundry

AndyRating, 5 stars3 weeks ago
My wife, daughter, and I had a great stay at Kylee's North Rockaway unit. The location was tough to beat being so close to the beach with plenty of good restaurants to choose from. The space is relatively small, but it had everything we needed for a nice getaway to Mission Beach. We found the shared garage space was tight (we had a standard sedan) but it was sure better than trying to find public parking. The available beach gear was an added bonus. I would recommend this unit 10/10!

Quick stats about guest house rentals in San Diego

  • Total rentals

    1K properties

  • Total number of reviews

    1L reviews

  • Family-friendly rentals

    140 properties are a good fit for families

  • Pet-friendly rentals

    240 properties allow pets

  • Rentals with a pool

    90 properties have a pool

  • Rentals with dedicated workspaces

    540 properties have a dedicated workspace

Destinations to explore