Guest house holiday rentals in San Diego County

Find and book unique guest house rentals on Airbnb

Top-rated guest house rentals in San Diego County

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

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Guest favourite

Guest house in Escondido

4.92 out of 5 average rating, 639 reviews

Hilltop cabin retreat with lake & mountain views

Rustic hilltop cabin overlooking Lake Hodges. Surrounded by open canyons & mountains, you will feel like you're a million miles away from everything as you take in the views from the cabin, deck or the outside shower, swim in the saltwater pool, or relax by the fire bowl. A short walk to lake with boating, fishing & miles of hiking/mountain biking trails. Property offers swimming pool, fire bowl, and shaded arbor. SD Zoo Safari Park, wineries, breweries, & ocean beaches all within easy reach.

13–20 Sep

₹14,285 per night

Guest favourite

Guest house in Valley Center

4.91 out of 5 average rating, 211 reviews

North San Diego Serenity

* Due to recent flu outbreaks we close the 2 days before and after booking for our safety and our quests. We are also a 2 guests max occupancy. I do require reviews to book. New Flooring!! Thank you Quiet Country GH w/beautiful Mt views . 45 Min to SD airport w/ Pala , Valley View & Casinos just 15 min. Local winery's and Brewery's 20 min. Parks & nature trails around the area, sunsets are free! Hills and scenic roads. SD Wild Park is 25 min . Comfortable! sleeps 2 Perfect . WIFI :-)

11–18 May

₹8,876 per night

Guest favourite

Guest house in Encinitas

4.98 out of 5 average rating, 126 reviews

The Tiki Lounge, Leucadia, California

The Lounge is a quaint, cozy 400 sq. ft. one-bedroom detached guesthouse with lots of character in the "funky" community of Leucadia. Located just east of historic Highway 101 in a quiet neighborhood a mile from beach access, you're close to many eclectic shops, restaurants and entertainment. You'll also have access to a semi-private patio and shared access to our back yard, where, as of June 2023, Debe works 3 to 4 days a week in her studio. We really love it here and think you will too.

9–16 Sep

₹11,486 per night

Guest favourite

Guest house in San Diego

4.93 out of 5 average rating, 356 reviews

Cozy Ocean Beach Casita

This cozy, clean casita is just 4 blocks to the beach, pier, great surfing, restaurants, bars, shopping, and Sunset Cliffs. You’ll love it for its walkability to everything you need. The casita is only 120 square feet, a very small space (small studio with everything in one room including the bathroom), for single occupancy only, but with everything you need to enjoy a San Diego getaway. It is great for solo travelers who want to be near the heart of Ocean Beach, San Diego, California.

3–10 Sep

₹9,166 per night

Guest favourite

Guest house in San Diego

4.97 out of 5 average rating, 283 reviews

Betty- Guesthouse near CBX & San Ysidro border

This comfy studio located in San Diego is the perfect spot for a quiet & cozy weekend retreat. Inside is bright & inviting with stylish spacious studio, private entrance from side gate, private patio with bbq & hanging hammocks; driveway parking spot & plenty of street parking! The view from the patio is very relaxing, making it the perfect weekend get away. Centrally located in a quiet & peaceful area within 5 minutes away from Plaza Las Americas & 10 minutes away from the CBX.

18–25 Jan

₹10,501 per night

Guest favourite

Guest house in Encinitas

4.86 out of 5 average rating, 228 reviews

Sunset/Ocean View Guest House! Minutes to Beach

Sunset/Ocean view guest house (one bedroom with a sofa bed)--386 Sunset Drive, 92024. Quiet residential neighborhood, close to downtown Encinitas, and half a mile from Moonlight Beach. Balcony features a propane barbecue, table, chairs, chaise lounge, and a distant view of the sunset and ocean. Living room/dining/kitchen area includes sofa bed. Living room features a 45" flat screen and DVD player. Bedroom includes a natural gas fireplace, television, and DVD player.

29 Dec – 5 Jan

₹12,281 per night

Guest favourite

Guest house in El Cajon

4.98 out of 5 average rating, 190 reviews

Fletcher Hills - modern 1 BR.Easy, no step access.

** 48 hours between check-ins. Thorough cleaning and sanitizing.. Four night minimum stay. Dogs ONLY are welcomed on a case by case basis. They must be house trained and are not permitted on any furniture. If you instant book, you must contact me about your pet within 24 hours. Smoking is permitted in the outside areas - patio, gazebo, yard. Easy freeway access helps any commute to downtown and area attractions. Having your own vehicle is the best way to get around..

1–8 Mar

₹10,015 per night

Guest favourite

Guest house in San Diego

4.98 out of 5 average rating, 185 reviews

North Park Garden Retreat Casita

Nestled between the urban neighborhoods of North and South Park, our sanctuary within the heart of the city is surrounded by a secret garden that gives the impression of a tropical oasis. The private casita is tucked in the backyard of the Host’s home and has french doors which open to the lush greenery of the garden. Whether vacationing, traveling for work, or looking for an ideal space for relaxation and renewal, this is the perfect place to enjoy your San Diego stay.

4–11 Sep

₹9,415 per night

Guest favourite

Guest house in San Diego

4.97 out of 5 average rating, 145 reviews

Modern 1-Bdrm with A/C, 15 min to beach

Bright and inviting one bedroom with a open floorplan combined kitchen and living room, with toaster oven, hot plate, microwave, Keurig, fridge, rice maker, and all the amenities of a boutique junior suite, including 1000 ct. sheets, hypoallergenic feather bed, snacks, bottled water, any toiletry you might need and plenty of beach towels. Stay for 3 days or for the guest that may need a longer stay it is perfect for transitioning to the San Diego area.

21–28 Aug

₹12,331 per night

Guest favourite

Guest house in Vista

5.0 out of 5 average rating, 199 reviews

New Tranquil Barn Retreat on a Peaceful Half Acre

The Buena Vista barn is a clean, quiet, and upgraded detached barn in Vista with everything you need for a peaceful and comfortable stay! Only 10 minutes to downtown Vista, you'll find great restaurants, breweries, shops, and a movie theater. Points of interest: • Downtown Vista: 10 minutes • Cal State San Marcos: 15-17 minutes • Beach: 20 minutes • Legoland: 22 minutes • Temecula and Wine Tasting: 30-40 minutes • Sea World: 47 minutes

7–14 Sep

₹12,433 per night

Guest favourite

Guest house in Dulzura

4.97 out of 5 average rating, 579 reviews

Vineyard & Winery Guest House

A hidden gem! Get away and stay at the historic pioneer era Clark Ranch established in 1885. Our guest house sits above our winery tasting room and has its own private entrance and driveway. It's clean, cozy, and self-contained . Make it a weekend 'getaway' stay and sample our fine wines , and Estate Olive Oil. There is a tower in the vineyard where you can enjoy a glass of wine and watch the sun set. Balcony overlooks Dulzura Creek.

10–17 Jan

₹11,897 per night

Guest favourite

Guest house in San Diego

4.97 out of 5 average rating, 190 reviews

California Cottage in North Park

Walking along side the main house into this secluded cottage, you’ll embark on your own vacay just 10 minutes from the airport. This converted separated garage is a home away from home with walking distance to University Ave with Communal Coffee for breakfast, and outdoor dinner dinning at Louisiana Purchase. If the zoo is what you desire, it is not a far walk but a little hike through the canyon is required.

3–10 Sep

₹10,601 per night