
Holiday rentals in Rochester
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Top-rated holiday rentals in Rochester
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Relaxation Station 0.7 Miles from Mayo King Bed
Your home away from home awaits! With 3 bedrooms, 1 bath, kitchen, living room, office space, and laundry room (all newly renovated), this home is perfect for you! A large backyard and patio, easy access to miles of walking trails and a park right across the street makes this home great for relaxing outdoors. Conveniently located 0.7 miles from downtown and Mayo makes it a perfect stay for guests visiting the clinic or other Rochester events. We look forward to warmly welcoming you to Rochester!

Woodland Retreat, Full private walkout lower level
Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Euro House, Bright! Near Mayo-Single Family Home
Welcome to your home away from home! This private, single-family home was thoughtfully designed and is located in a quiet area just 5 minutes (0.9 miles) from the Mayo Clinic. Step into a master gardener’s dream—a beautifully landscaped yard filled with native plants and outdoor seating, perfect for relaxing after a long day. 2 Queen Bedrooms, 2 Full Bathrooms, modern finishes throughout, Super clean and pet-free. Off-street parking, Washer & dryer, Wi-Fi, Smart TVs & Fully stocked kitchen.

Home for the Traveler, a walk to St. Mary's
This place is located near the heart of Rochester, within blocks of St. Mary's hospital, very peaceful, cozy and private. A lower-level unit in an older home, plenty of windows and light, and includes a gorgeous bedroom with a fireplace, a full kitchen, a reading room, and a clean, updated bathroom. This home is also close to the Apache mall, the Canadian Honker and other local restaurants, coffee shops, and the walking/biking trail system. There is also Wi-Fi, laundry, and parking on-site.

Mayo Downtown's Prairie Home Retreat
Nestled in a serene corner, this home offers a perfect blend of tranquility and accessibility; being near the Mayo campus and Rochester's key attractions. Enjoy comfortable beds, a well-appointed kitchen, and a fenced yard with patio gardens. It's an excellent spot for family bonding, featuring three smart TVs, rapid Wi-Fi, and a variety of indoor and outdoor entertainment options. We strive to accommodate flexible check-in/check-out arrangements whenever feasible. Rollator accessible.

NEW: Calming main floor retreat near Mayo Clinic
• Enhanced cleaning protocols due to COVID • Fully renovated apartment in winter 2019 • Main floor apt in quiet 4plex • 550 square feet with refinished hardwood floors throughout • La-Z-Boy power recline loveseat with power headrests and USB ports. Both sides also rock. • 65" Smart TV with DirecTV • Free off-street parking • 6 blocks north of Mayo Clinic • Walk-in shower • Queen bed • Full kitchen with gas stove and dishwasher • High-speed WiFI — 100+ MBPS • Shared laundry in basement

Restful sanctuary close to Mayo Clinic
This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

Cozy, comfy 1 BR unit in triplex, 4 blocks to Mayo
This is a 1 BR unit that is in the lower level basement of a triplex (564 sq. ft). There are eight steps down to this apartment. It is bright and clean. This triplex is located in the Kutzky park neighborhood, a safe, quiet residential area. Free off street parking is available behind the house. The apartment has a complete kitchen with a stove, a refrigerator, plenty of dishes and pots and pans so you can make your own meals. There has an electric fireplace Wifi and a smart TV.

Spacious Modern Home Near Mayo, St. Mary's Campus
- 5 min walk to Mayo Clinic, St. Mary’s campus - 3 bedrooms, 3 bathrooms, and a loft - unique design with vaulted ceiling and skylights in the style of Frank Lloyd Wright, one of its kind in the whole neighborhood - two-car garage + another dedicated parking space outside - walkable and safe family-friendly neighborhood close to downtown and all amenities - outside front and back patios - fusball play table - dedicated workspace - high speed wifi - Apple TVs - washer and dryer

Hygge House | A Cozy Guesthouse
The Hygge (pronounced hyoo·guh) House is a tiny taste of Scandinavia in Southeastern Minnesota. What is Hygge? In short, it's a Scandinavian way of living that focuses on hunkering down and creating a safe, comforting and warm place to while away. My husband and I hand built the Hygge House with your comfort in mind. We love being cozy and having space to spend together so when the opportunity arose to renovate our studio, we wanted to share it!

Modern and fresh space very close to Mayo Clinic
Completely updated duplex! I put all my time, energy, and money to make this property perfect for my guests. I am a lifelong carpenter so I take pride in my work. I have painted every surface.(walls and ceilings) New appliances, sinks, curtains, trim, lighting and cabinets. There are many restaurants within blocks and a Walgreens a block away. I have put everything into making this space perfect for my guests so I expect all guests to respect it.

Cozy home next to Mayo Clinic & historic parks!
Cozy single level 2 bedroom, 1 bath. Fully furnished kitchen with TV, WiFi, and smart lock. It’s a 1.6 miles to Mayo Clinic. Walking distance to Historic Quarry Hill Park and Silver Lake Park. City bus line to Mayo Clinic 1/2 block away. Newly remodeled bathroom with full linen and toiletries. Quiet neighborhood, with full driveway parking. We also have a baby gate for the stairs. Enjoy your next home away from home !
Popular amenities for Rochester holiday rentals
Other great holiday rentals in Rochester

Tranquil 2Bed/2Bath w/Balcony near Mayo

Remodeled 1 bedroom house - Close to Mayo Clinic

New! MN Comforts The Heart 4Bd/2Bth, 12min to Mayo

Kaleidoscope Flat 1 bd 1 mi to Mayo, Free Parking

Luxury Cottage | 5 Blocks from Mayo | No Stairs!

The Don

Fresh space near Mayo Clinic and downtown

Unit 2365J | 2bd/2bth | Single-Family Home
Quick stats about holiday rentals in Rochester
Total rentals
670 properties
Nightly prices starting at
₹1,760 before taxes and fees
Total number of reviews
33K reviews
Family-friendly rentals
440 properties are a good fit for families
Pet-friendly rentals
220 properties allow pets
Rentals with a pool
30 properties have a pool
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- Treasure Island Resort & Casino
- Whitewater State Park
- Perrot State Park
- River Springs Water Park
- Red Wing Water Park
- coffee mill ski area
- Faribault Family Aquatic Center
- Four Daughters Vineyard & Winery
- Salem Glen Winery
- Maiden Rock Winery & Cidery
- Villa Bellezza
- welch village
- Garvin Heights Vineyards
- Falconer Vineyards
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