Guest house holiday rentals in Southern United States
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Southern United States
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Southern United States
Family-friendly guest house rentals
Guest house in Gold Hill
4.8 out of 5 average rating, 340 reviewsPeaceful Romantic Cabin In Nature With Jacuzzi tub
15–22 Nov
Guest house in Corrales
4.98 out of 5 average rating, 459 reviewsLa Cottage
5–12 Sep
Guest house in Vero Beach
4.9 out of 5 average rating, 310 reviewsCharming, Barn Apartment on Farm, with Animals
4–11 Jul
Guest house in Atlanta
4.86 out of 5 average rating, 281 reviewsComfortable Guesthouse in Candler Park
15–22 Jul
Guest house in Elgin
4.89 out of 5 average rating, 347 reviewsCharming Country Guesthouse with Chickens
15–22 May
Guest house in Norman
4.94 out of 5 average rating, 102 reviewsGUEST HOUSE 1.5 miles to OU CAMPUS
3–10 Sep
Guest house in Santa Fe
4.89 out of 5 average rating, 107 reviewsCasita de Luxx: King Bed, Pool, Hot Tub, Views
8–15 May
Guest house in Biscayne Park
4.94 out of 5 average rating, 451 reviewsCozy and charming cottage
2–9 Dec
Guest house rentals with a patio
Guest house in Jacksonville
4.92 out of 5 average rating, 185 reviewsThe Moody Loft (Murray Hill)
16–23 Jul
Guest house in Yellow Springs
4.99 out of 5 average rating, 207 reviewsModern Remodel Steps to YS, Glen, & Antioch
3–10 Nov
Guest house in Cocoa Beach
4.98 out of 5 average rating, 203 reviewsThe Cocoa Boho Rooftop Retreat
30 Aug – 6 Sep
Guest house in Orlando
4.88 out of 5 average rating, 219 reviewsCouples Oasis *Heated Pool* and Lake View
21–28 Aug
Guest house in Glen Burnie
4.94 out of 5 average rating, 263 reviewsThe Crab House - a Private, Waterfront Guest House
16–23 Oct
Guest house in Watkinsville
4.99 out of 5 average rating, 119 reviewsDowntown guest house with private hot tub & deck
19–26 Jul
Guest house in Harvest
4.94 out of 5 average rating, 191 reviewsCozy Cottage Tiny House Cabin |Private Porch
18–25 Jul
Guest house in Broken Arrow
4.95 out of 5 average rating, 209 reviewsThe Pool House: King Bed & Hot Tub
10–17 Sep
Guest house rentals with a washing machine and dryer
Guest house in Newark
4.94 out of 5 average rating, 296 reviewsCherry Valley
25 Dec – 1 Jan
Guest house in Round Top
4.98 out of 5 average rating, 191 reviewsThe Horseshoe Cottage
19–26 Jul
Guest house in Atlanta
4.87 out of 5 average rating, 787 reviews❤️️ Independent Guest House & Huge Outdoor Space
2–9 Aug
Guest house in Wilmington
4.95 out of 5 average rating, 188 reviewsHaven: Intimate Treehouse on the Ground
5–12 Nov
Guest house in Alpharetta
4.99 out of 5 average rating, 301 reviewsOwl Creek Chapel
7–14 Oct
Guest house in Orlando
4.98 out of 5 average rating, 350 reviewsLakefront Seclusion modern guesthouse+Pool+Hot tub
14–21 Nov
Guest house in Wilmington
4.96 out of 5 average rating, 488 reviewsCrestwood Cottage
7–14 Aug
Guest house in Tuckasegee
4.99 out of 5 average rating, 177 reviewsWolf Lake Escape - lake & mountain retreat
2–9 Feb
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