
House holiday rentals in Seneca
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Top-rated house rentals in Seneca
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Popular amenities for house rentals in Seneca
House rentals with a pool

Peaceful Mountain at Sapphire Valley
Well, my husband and I have stayed there on and off for the last six months for local work, so we know the place well. Sadly, our project has come to an end, so our most recent stay will be our last for work. BUT, we love everything about Todd and Barbie and the house, and we will be back for fun hiking weekends. Hiking, waterfalls, everything nearby. It's the best place we've stayed in the area. Private, squeaky clean, big deck, large dining room table for big meals or spreading out the paperwork, GREAT internet connection and TV options. We'll definitely be back on our own - we feel so comfortable there in every way. I could not recommend any higher - would give it a "10" if I could. Todd and Barbie also bent over backwards to help us with a couple of last-minute schedule changes. Such honest and thoughtful hosts. Thanks Todd and Barbie for EVERYTHING over the last few months. We love you guys!

Your Lakeside Family & Dog Retreat Awaits!
I couldn't be more pleased with my first AirBnB stay. The place was clean, inviting, and well-stocked. I wasn't expecting spices, dog toys, dog bowls, dog cot, etc. The fully fenced in yard, lake access, available kayaks, and privacy are the only things I wanted and this place sure supplied! the hot tub, outdoor shower, and firepit were huge bonuses. Also, met and talked with the neighbor who is super friendly 😉 I stayed alone the first half with my dogs and got my peace in. The second half a couple girl friends joined and we thoroughly enjoyed paddling out the this little island and throwing rocks, trying to fish, etc. Enjoying using the coloring supplies, games, and grill as well! It did storm most of the week, but even that was enjoyable! 10/10 experience for us all.

Pet + Family Friendly 4BR Pool House Near Furman
Lots of space for our family, well stocked kitchen with snacks and drinks. Really enjoyed the pool and grill!

Sunsets and Siestas -Lake Keowee home near Clemson
Our family of 5 couples and 2 small children loved our stay at Sunsets and Siestas. The home has lots of space, the family suite was a big hit, the master suite is beautiful and spacious, the kitchen very well appointed and the decks, patios are excellent. We used the boat slip including the lift as well as the kayaks and paddleboards. The home had everything we needed and then some. We would definitely return.

Lake Keowee Access-Dock-Pool-Grill-Clemson 17 Min
We were there for a work trip and it was a very comfortable place to stay. Clean, quiet and relaxing. Will definitely stay again!

Wonderful mountain cottage with amazing view!
This is such an amazing place and yes it is real! Incredible views and wonderful stunning home in the mountains. It really was a memory I'll have forever. Matt was so awesome, he helped us get settled in and the amenities were so awesome🙏. Stay here and prepare to be pampered all the way up in the mountains! ❤️

Mountain Laurel Retreat
Very pleased with the cleanliness & accommodations. Lovely home!

Enchanting 1906 Farmhouse
This farmhouse vacation was the best our family has experienced so far. We have stayed at over 15 rentals via this platform and others but by far this was the best. If Amy could have controlled the weather, then the trip would have been unbelievable. The house has everything a person needs to stay comfortably. The location is peaceful. The animals come up to the fence each morning and night and allow you to pet them. One horse wants all the attention....lol. The donkeys allow you to give them love too. The house had a full kitchen, a bar area, large living room and 4 beautiful and well-furnished bedrooms. The pool was nice but only used 3 days since we had rain most days. If a person has a small group of 10ish people, this is the perfect house for you. The small neighboring towns have things to see and do. So many waterfalls in the area. You definitely won't be disappointed if you choose to go to Seneca and stay at this house. Amy, thank you for sharing your home!
Weekly house rentals

Good Times @ Clemson / Lake Hartwell
Mike was a great host. Mike even came to the house and dropped off a few items that we needed. The house was great and as described. The house has everything you need and has a easy walk to the waterfront. Minutes from the Clemson Marina if you need a boat or restaurant. There was plenty of room for a family. We HIGHLY recommend Mike's house and we would stay here again. 5 Stars.

Lake Hartwell Beauty with Dock. Minutes to Clemson
We stayed here for my son's graduation from Clemson. It was the perfect place! The house is beautiful and being right on the lake made it feel like we were on vacation. We were able to have a graduation BBQ at the house, which was way better than fighting the crowds at a restaurant. It is about a 15 minute drive to campus so a little bit of a drive but not too bad. Jessica was very responsive to any questions and the house was beautiful! I would highly recommend!

Cozy Clemson Hideaway • 5 min to Campus • Wi-Fi
Thoroughly enjoyed our stay at Christina’s. Her home was perfect! Kitchen is well stocked, beds were comfortable, very clean and felt like home! It is close to Clemson which is why we were there. We didn’t have any issues and we would recommend staying there.

Cozy Cottage
Cute place fairly close to Clemson. Lovely private dock on a beautiful lake. Beds are so comfy and everything seems very new and well maintained. Well stocked, all you need!

Lake House Retreat Near Clemson
The house was beautiful and had plenty of space for the whole family. The bunk room was a hit with the kids as well. Our whole stay was incredible and will definitely keep this property in mind for any future rental needs.

Modern Mountain Stream Overlook
Great stay in Highlands! A few things to note - the mile drive after you get off the main road is gravel and there’s no service. There was also no Uber/Lyft but we were driving so no issues there. Just a couple things to plan for during your stay! Overall, amazing place, extremely clean, & great communication with host. Would 100% stay here again!

Golf view, lake access, 3 pools!
We had a wonderful stay at the Sail Loft over Memorial Day weekend! From the moment we arrived, we felt right at home. The space is so cozy, beautifully decorated, and full of thoughtful touches—it’s clear that every detail has been carefully considered. It’s just like the photos, only better in person! Nichole was the perfect host—kind, responsive, and welcoming. She guided us throughout our stay, making sure everything went smoothly and that we felt comfortable and cared for. We loved enjoying the Keowee Key amenities, especially the pool and dining at the club’s restaurants. It truly felt like a hidden gem! We’re already looking forward to coming back soon. Highly recommended for anyone looking for a peaceful retreat with all the comforts of home!

Waterfall Cove - East
We loved the place! The waterfall and private cove were great! We were slightly confused about where our rental ended and others started and what the common areas were. Once I asked, everything was clear. My wife loved the Happy Anniversary card when we arrived. The amenities were perfect and up to date. The bed was very comfortable with the new, adjustable mattress and base. We loved the 2 head shower, although the time it took to get hot water was a little long. Thank you for hosting and sharing this beautiful slice of heaven to get away from "civilization"!
Private house rentals

Stay ON a waterfall‼️ With Hot Tub‼️
Our stay was so relaxing and the natural scenery on all the grounds was so beautiful. No fish but trout fishing in the mountain stream was fun! The house was so clean, and the hot tub, sauna, and outside kitchen were big hits. Our Host was so friendly and helpful. Hope to go back again.

Electric city downtown escape
Nice house can’t complain give it a try I hope everyone enjoys the same as I did

Lakefront Keowee Luxury Cottages 127
We stayed at the Keowee Luxury Lake Cottage for 10 days. It is in a great location. The Marina is right next door, so it was easy to rent a boat (they offer a discount for people who rent a cottage). The lake is beautiful, the cottage very comfortable and the host was super responsive to any question. We would definitely stay here again!

Lakefront home, level yard ,dock on quiet cove
The home and setting is absolutely perfect. We came from KY, NY, SC and Spain to celebrate Christmas in a rare opportunity with family. We were fortunate to bring our two fur babies (don’t leave home without them) and enjoy the short stay for this occasion. Anytime here is a good time to unwind and relax.

Whitewater Lake Front Cottage
Great location! We had so much fun staying here, caught a pretty big bass on the lake, had a lot of fun on the paddle boat, home was beautiful and perfect sized for 2. Kitchen was stocked with goodies and had a variety of appliances to cook with. And Dustin was quick to reply anytime we had questions or needed anything. Would recommend and stay again for sure!!

The House on the Hill in Seneca
Stayed here for 2 weeks while we were in moving process. House is in quiet neighborhood and was very peaceful. Furniture and bedding was very comfy and we slept very well. The fenced in backyard was perfect for my dog, which was great not having to take my dog out on a leash to use bathroom. We will definitely stay here again when needed.

Point Lot, Boat and PWC Rental
The house is great, the location and view are perfect, and the host is very helpful and responsive. The house had a lot of great amenities, perfect for a family. Boat rental was super easy, and we enjoyed using the kayaks and standup paddle boards. Our young children loved the beach area, and the adults enjoyed the Hottub. The lake, of course, is beautiful, and the fishing good as well. We’ll definitely return.

Cozy cottage on deep water cove.
This was a wonderful, peaceful staycation! Home is beautiful and just as described the private dock is immaculate!
Quick stats about house rentals in Seneca
Total rentals
30 properties
Nightly prices starting at
₹3,471 before taxes and fees
Total number of reviews
1.5K reviews
Family-friendly rentals
20 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
10 properties have a dedicated workspace
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- Black Rock Mountain State Park
- Gorges State Park
- Table Rock State Park
- Tallulah Gorge State Park
- Helen Tubing & Waterpark
- Mountaintop Golf & Lake Club
- Bell Mountain
- Tugaloo State Park
- Jump Off Rock
- Don Carter State Park
- Wade Hampton Golf Club
- Anna Ruby Falls
- Victoria Bryant State Park
- Old Edwards Club
- Funopolis Family Fun Center
- Ski Sapphire Valley
- Discovery Island
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- Louing Creek
- Victoria Valley Vineyards