Holiday rentals in Seneca

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Top-rated holiday rentals in Seneca

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Guest favourite
Campervan/Motorhome in West Union
4.93 out of 5 average rating, 177 reviews

Hot Tub, Firepit, Projector, No Extra Fees/Chores

Escape to this enchanting bear themed camper, nestled on a cozy one acre wooded lot. While another camper is nearby, a privacy fence creates your own peaceful haven. Soak in the hot tub on the covered deck, with a towel warmer and movie projector adding to the fun. Ideally located between three cities, you’re just minutes from shopping, dining, lakes, waterfalls, and scenic hiking trails. Cap off your evening by the firepit, roasting marshmallows under a starlit sky. Your serene getaway awaits!

Guest favourite
A geodesic dome is illuminated from within, set against a backdrop of trees. An adjacent wooden structure features outdoor seating under string lights, creating a welcoming atmosphere for relaxation. The natural environment is highlighted, emphasizing the dome's unique design.
Dome in Salem
4.89 out of 5 average rating, 335 reviews

G.O.A.T. Geodome: Farm Animals, Hot Tub, Zip Line

Glamping: where luxury meets the outdoors. This geodesic structure offers a rare opportunity to experience the outdoors without the elements. Complete with kitchen, AC & heat, dual control heated mattress pad, fully functioning bathroom, and sunrise views over the pasture. Whether you are looking to relax and enjoy feeding the farm animals, have an adventure riding the zip line, or indulge in a romantic evening sipping wine in the hot tub under the stars, you will leave with lasting memories.

Top guest favourite
The cottage exterior displays warm wood siding with large windows allowing natural light. A welcoming front porch features two chairs and a small plant, while a grill stands nearby. Surrounding landscaping creates a serene atmosphere in a private setting.
Cottage in Central
4.99 out of 5 average rating, 182 reviews

The Wildflower

Enjoy a relaxing experience at this centrally-located spot, away from the hustle and bustle but only 6 min from Clemson (10 min from Clemson University), nestled in the country in a peaceful, safe neighborhood with lots of privacy surrounding. The cottage has a front porch with 2 chairs, a 2 person hammock, grill, and a fire pit (wood is provided) with three lawn chairs. There’s a queen bed and also a CordaRoy beanbag (*bed #2) that opens up to a soft bed that sleeps 1 adult or two children.

Top guest favourite
A treehouse surrounded by trees glows gently with warm lights in the evening. Two Adirondack chairs are positioned around a fire pit, with a small table nearby. The forest setting offers a calm and inviting atmosphere for outdoor relaxation.
Treehouse in Mountain Rest
5 out of 5 average rating, 438 reviews

THE BELLA LUNA Romantic Treehouse - Outdoor Shower

This is the perfect ROMANTIC ESCAPE! Located in the Sumter National Forest the Bella Luna is just 5 minutes from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and Stumphouse Mountain Bike Park and within an hour of Clemson, Lake Jocassee and Clayton, GA. Our romantic retreat features carefully curated vintage furnishings, an outdoor shower, napping net, relaxing seating areas and an outdoor fire pit stocked with firewood and a S’mores kit! We can't wait to host you!

Guest favourite
A studio apartment is seen from a corner, featuring a kitchen with orange cabinetry and stainless steel appliances. Two armchairs and a small dining table are positioned in the living area, with a television mounted on the wall. Ample lighting and a neutral color palette are present.
Home in Pendleton
4.87 out of 5 average rating, 100 reviews

Basement apartment in Pendleton w/ sep. entrance

This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Guest favourite
A cozy bedroom is highlighted by a spacious bed with a patterned blanket. Two bedside lamps provide soft illumination on either side. A wooden dresser is positioned against the wall, and a window allows natural light to fill the space, complemented by cream-colored walls.
Flat in Seneca
4.94 out of 5 average rating, 173 reviews

Clemson Mom Apartment

Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

Top guest favourite
A charming home is presented in a serene neighborhood setting, featuring a well-maintained lawn and flowering shrubs. The exterior showcases a light-colored façade with a welcoming front porch and a spacious driveway leading to a two-car garage.
Home in Seneca
4.99 out of 5 average rating, 217 reviews

The Cozy Cottage

Beautiful, well-maintained home located in a private subdivision just minutes away from shopping, restaurants, lakes, golf courses, and Clemson University. This home has a fully equipped kitchen for dining in and a back patio for grilling out. The backyard overlooks a peaceful wooded area, providing a serene and private escape. Our home offers the perfect blend of tranquility and convenience. Perfect for getaways, football weekends, graduation, and other Clemson University events!

Guest favourite
A charming exterior view of the Tiny Treehouse features a bright red roof and wooden siding with a sunflower design. A picnic table sits on the lawn, surrounded by green grass and trees. A lounging area with rocking chairs is nearby, providing a welcoming outdoor space.
Tiny home in West Union
4.95 out of 5 average rating, 270 reviews

Holliday's Inn Tiny Tree-house

Tiny Treehouse is a ‘container’ house set in a private wooded locale at the foothills of the mountains. Find yourself hiking at Oconee State park or Caesar's Head mountain along with a multitude of waterfalls within our county. 5 minutes from downtown historic Walhalla, 10 minutes to city of Seneca, and 20 minutes from Clemson University where tailgaters unite before the big football game! Explore the artistic venues and cultural scenes of Greenville just an hour away!

Top guest favourite
A modern cottage features a spacious covered porch with string lights, surrounded by a lush green lawn. Large glass doors invite natural light into the interior, while tall trees provide shade in the background against a colorful sunset sky.
Cottage in Anderson
4.97 out of 5 average rating, 189 reviews

Lakefront dock *hot tub* Anderson Clemson King bed

Relax & enjoy the beautiful views of lake Hartwell from the front porch daybed swing, hot tub, or private dock. Sleep in a king size bed wrapped in cool cotton linens, a towel warmer, soaking tub with TV, & a breville espresso maker. Located w/i 10 minutes of many restaurants. Less than 20 min. to downtown Anderson Pendleton or Clemson. This prime location on lake Hartwell is a 10 minute boat ride to Portman Shoals Marina, the Galley restaurant, & Green Pond Landing.

Top guest favourite
The exterior of a modern tiny house is depicted, featuring a dark blue façade and large windows allowing natural light to fill the interior. The covered porch is accessible from the gravel pathway, and greenery surrounds the property, enhancing the wooded setting.
Cottage in Westminster
4.97 out of 5 average rating, 594 reviews

Tiny house

BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.

Top guest favourite
A charming tiny house is set amidst wooded surroundings, featuring a welcoming entrance with a white door and a light-colored roof. Two white chairs and a small table are positioned on a wooden porch, complemented by a grill nearby. Lush greenery enhances the tranquil setting.
Tiny home in Seneca
4.96 out of 5 average rating, 225 reviews

Windmill Cottage

You’ll treasure your time at this cute little cottage. It is 295 sq feet and was built in 2023 at the edge of the woods on our property. It has a full kitchen, bedroom with a queen bed, bathroom and living room. It is perfect for one or two people, for either a quiet get-away in the country or for someone who is in town for work and is looking for a more extended stay. We offer discounts for weekly/monthly stays!

Top guest favourite
A charming cottage is surrounded by lush greenery and tall trees, featuring a welcoming front porch with seating. The exterior is clad in grey siding and highlights stylish architectural design elements. A gravel driveway leads up to the house, emphasizing its peaceful and private setting.
Home in Seneca
5 out of 5 average rating, 101 reviews

The Cottage

Come relax and refresh in peaceful surroundings. Relax and unwind on the front porch. Experience tranquility as the sun sets and the frogs start croaking. You are welcome to cast a line in the pond to try your skill at fishing. Fishing poles are not provided. The cottage is private but still has convenience of Walmart and Oconee Memorial Hospital within a 5 minute drive. We are 13 miles from Clemson.

Popular amenities for Seneca holiday rentals

Quick stats about holiday rentals in Seneca

  • Total rentals

    60 properties

  • Nightly prices starting at

    ₹3,521 before taxes and fees

  • Total number of reviews

    2.3K reviews

  • Family-friendly rentals

    50 properties are a good fit for families

  • Pet-friendly rentals

    20 properties allow pets

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  1. Airbnb
  2. United States
  3. South Carolina
  4. Oconee County
  5. Seneca