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Guest house holiday rentals in Mission Bay, San Diego

Find and book unique guest house rentals on Airbnb

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Popular amenities for guest house rentals in Mission Bay, San Diego

Family-friendly guest house rentals

Guest favourite
Guest house in La Jolla
4.79 out of 5 average rating, 193 reviews

San Diego Shangri-La

EricRating, 5 stars3 weeks ago
I really enjoyed staying here. It's on a canyon, which provided a great view and a nice breeze and was very quiet. We had our little dog with us and he loved being able to explore the yard. It's a great location in La Jolla / North PB. It's at the top of my list for my next trip to San Diego.
Top guest favourite
Guest house in Hillcrest
4.98 out of 5 average rating, 166 reviews

Hidden Casita with Private Deck & Patio

SamanthaRating, 5 stars3 weeks ago
We had such a lovely time at Jane's casita. It was so quiet, walkable to everything, and peaceful. Lots of birds to be seen from the patio. I'm glad we stayed here for our San Diego vacation and would definitely stay here again! Cute decor, too :)
Top guest favourite
Guest house in Greater North Park
4.97 out of 5 average rating, 186 reviews

New Guest House - North Park

KrystenRating, 5 stars3 weeks ago
Lynae’s place was wonderful, as was Lynae! Balboa park right nearby, with gorgeous trails and scenery. Walkable to North Park area which had a fun variety of bars, shops, and restaurants. Lynae was a wonderful host - responsive, kind, flexible - and the home was bright, airy, with gorgeous views. We couldn’t say enough good things about the wall of jasmine walking in. Thank you Lynae for having us in your home!
Guest favourite
Guest house in Point Loma Peninsula
4.93 out of 5 average rating, 659 reviews

OB studio, ocean views, hot tub & garage parking!

JesseRating, 5 stars1 month ago
Amazing stay at La casita !! Scott was an amazing host , had a binder of stuff to do locally and super attentive ! Will definitely be staying at La casita soon again
Superhost
Guest house in Pacific Beach
4.78 out of 5 average rating, 393 reviews

Law Street Retreat

HilaryRating, 5 stars2 weeks ago
Great, central location with everything we needed for a leaping off spot. Thanks!
Top guest favourite
Guest house in Sherman Heights
4.96 out of 5 average rating, 533 reviews

Romantic Private Garden Studio Near Downtown

HéctorRating, 5 stars3 weeks ago
Kathi and Byron are great hosts and the place is beautiful, exactly as described. We had a great time, the place is very close to everything, there is a liquor store just 1 block away, very comfortable bed, beautiful garden 😃😃😃😃 Thank you very much Kathi, we hope to come back soon to San Diego and we will definitely book your place again.
Top guest favourite
Guest house in University City
4.92 out of 5 average rating, 451 reviews

Garden Cottage | 200Mbps | Sofabed | 55”TV | Patio

LeslieRating, 5 stars1 week ago
We had a great stay, the cottage was so cozy and felt right at home. The garden outside of the cottage was absolutely beautiful. Thank you again Donna for hosting us!
Guest favourite
Guest house in Kensington
4.97 out of 5 average rating, 582 reviews

Central & Serene Secret Garden Guesthouse

JenniferRating, 5 stars3 weeks ago
We loved Susie’s garden guesthouse! Very walkable to a lot of lovely restaurants and close to SDSU!

Guest house rentals with a patio

Top guest favourite
Guest house in Talmadge
4.99 out of 5 average rating, 208 reviews

Adorable cottage in Talmadge

NysaRating, 5 stars1 week ago
The place was exactly as described. It was clean, peaceful and private. Their landscape was beautiful with all of the different flowers. Carlos was great with communication and a pleasure to interact with. He made things as simple and straightforward as possible. We would definitely stay at his lovely place again.
Top guest favourite
Guest house in La Jolla
4.97 out of 5 average rating, 117 reviews

Free Bikes. 5 min walk to Windensea Beach La Jolla

ChristinaRating, 5 stars6 days ago
We had a great stay at Carolina's property. The property looks exactly like the pictures (really cute and bright) and any amenity that you might need was provided. Carolina is quick to communicate and very helpful. We will definitely return!
Top guest favourite
Guest house in La Mesa
4.99 out of 5 average rating, 115 reviews

Private 1 BR Paradise retreat

AlleshaRating, 5 stars1 week ago
Jeanne and John's place was exactly as advertised in the description and photographs. The backyard and pool were beautiful unfortunately the weather and our schedule of events did not permit us time to indulge. If we ever needed a place in the area again we would definitely reserve another stay. We felt so welcomed and the extras were so thoughtful...like a balloon for my husband's birthday and a handwritten welcome letter. Thank you for the hospitality!
Guest favourite
Guest house in Point Loma Peninsula
4.94 out of 5 average rating, 126 reviews

Sunset Cliffs Studio

KatieRating, 5 stars2 weeks ago
Location was amazing, super close to the coast, restaurants, market, freeway. I loved spending time at Sunset Cliffs watching the surfers! Bed was comfy, and Mary was responsive, kind, and helpful. I was a single traveler, and felt like there was plenty of space for me. If you're not planning on spending too much time there, it could be doable with 2 adults, but tight. Note that the bathroom/shower area is not well lit, if you need that for safety reasons. Overall, I enjoyed my stay, and would consider this airbnb again in the future!
Guest favourite
Guest house in Sherman Heights
4.86 out of 5 average rating, 144 reviews

Downtown Cottage Minutes to Gaslamp & Petco Park

AustinRating, 5 stars1 week ago
Great place to stay if you’re in town by yourself. Walkable to the convention center ~20 mins. Easy to get in and out of and quiet at night.
Top guest favourite
Guest house in Golden Hill
4.98 out of 5 average rating, 162 reviews

Cozy Urban Casita! Near Zoo, Gaslamp and Coronado

LindaRating, 5 stars2 days ago
Absolutely the best! (And I'm a super-host too) Location, amenities, communication, just total thoughtfulness on Laurie's part made this the perfect San Diego getaway place for this retired active peaceful couple. If you have the privilege of staying here you'll feel like you came across magic.
Top guest favourite
Guest house in San Diego
5 out of 5 average rating, 108 reviews

SDSU Central Cozy Casita | Fast Wi-Fi | Walkable

DianneRating, 5 stars6 days ago
I stayed from Monday and checked out on Friday morning. Nancy was accommodating, she worked with me in allowing both my son and I to check in early. Respectful and responded to my messages immediately. The area was good, never had a difficult time with parking. Street parking was available in front of the property which was convenient. Quiet area. The place was exactly what the pictures shows. I would definitely recommend and will rebook for my next trip to San Diego.
Top guest favourite
Guest house in Point Loma Peninsula
4.93 out of 5 average rating, 116 reviews

Charming Casita with City and Bay Views

LenoreRating, 5 stars3 days ago
Our hosts were extremely gracious, helpful and available. The casita was as advertised (clean and charming). The yard full of plants was very serene and charming. We would definitely stay here again!

Guest house rentals with a washing machine and dryer

Top guest favourite
Guest house in Point Loma Peninsula
4.98 out of 5 average rating, 103 reviews

Casita at the Cliffs

J. DominicRating, 5 stars3 days ago
Amazing. Our host Libby was incredible, she made us feel very welcome. The place is wonderful, great location, clean, and stocked with everything we needed. Ocean Beach is a great find for those looking to for an SD beach location but are overwhelmed by the Mission and Pacific beach crowds.
Guest favourite
Guest house in Hillcrest
4.89 out of 5 average rating, 204 reviews

Relaxing Oasis - short walk to shops & recreation

MindyRating, 5 stars3 weeks ago
Super awesome location! Loved being able to walk to Balboa park and the Farmers Market!
Guest favourite
Guest house in City Heights
4.98 out of 5 average rating, 135 reviews

Private Guest House for 2 with Kitchen + Laundry

ArleneRating, 5 stars1 month ago
The place was exactly as described! Paid for a place with far less amenities for the exact same price range so definitely recommend this one!
Guest favourite
Guest house in La Jolla
4.98 out of 5 average rating, 418 reviews

Beautiful Private Villa walk to beach

ChristineRating, 5 stars3 weeks ago
We loved staying at Kim’s villa, we were comfortable and very much at home. We slept well and loved the surroundings. Thank you Kim, will definitely be back!
Superhost
Guest house in Pacific Beach
4.92 out of 5 average rating, 200 reviews

Brand New Cozy Detached Casita w/AC & heat

Maria & AndrewRating, 5 stars1 week ago
A very nice place if you in PB with 2 off street parking spaces !!
Guest favourite
Guest house in Pacific Beach
4.85 out of 5 average rating, 245 reviews

Sea Star Cottage

AshleeRating, 5 stars6 days ago
Cottage was perfect for my daughter and I. Centrally located to all the sites we wanted to see. Every adventure was an easy drive. Place was in a nice, quiet neighborhood. Clean, comfortable, and pleasant.
Guest favourite
Guest house in Point Loma Peninsula
4.87 out of 5 average rating, 100 reviews

Point Loma Oasis - Blocks From Sunset Cliffs

StephenRating, 5 stars3 days ago
Great location, moments away from Sunset Cliffs and Ocean Beach. The unit was exceptional and easy to find . We were only there for one evening but it was peaceful and quiet and the entire area is beautiful. The communication from the host was on point . Highly recommend
Guest favourite
Guest house in Bay Ho
4.94 out of 5 average rating, 124 reviews

Private San Diego Guest House - Beautiful View

RitbuneRating, 5 stars2 weeks ago
This place lived up to all the other great reviews. It was very peaceful, felt like home away from home, quiet, private, clean. Close to shops and the highway and a good location for San Diego visitors. Easy parking. Laundry available. Everything you need to feel comfortable. Denelle is great at communicating and providing clear details. I would stay here again!

Quick stats about guest house rentals in Mission Bay, San Diego

  • Total rentals

    20 properties

  • Nightly prices starting at

    ₹10,385 before taxes and fees

  • Total number of reviews

    2.8K reviews

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wifi availability

    20 properties include access to wifi

  • Popular amenities

    Kitchen, Wifi and Pool

Destinations to explore