
Guest house holiday rentals in Mission Bay, San Diego
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Top-rated guest house rentals in Mission Bay, San Diego
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
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Popular amenities for guest house rentals in Mission Bay, San Diego
Family-friendly guest house rentals

San Diego Shangri-La
I really enjoyed staying here. It's on a canyon, which provided a great view and a nice breeze and was very quiet. We had our little dog with us and he loved being able to explore the yard. It's a great location in La Jolla / North PB. It's at the top of my list for my next trip to San Diego.

Hidden Casita with Private Deck & Patio
We had such a lovely time at Jane's casita. It was so quiet, walkable to everything, and peaceful. Lots of birds to be seen from the patio. I'm glad we stayed here for our San Diego vacation and would definitely stay here again! Cute decor, too :)

New Guest House - North Park
Lynae’s place was wonderful, as was Lynae! Balboa park right nearby, with gorgeous trails and scenery. Walkable to North Park area which had a fun variety of bars, shops, and restaurants. Lynae was a wonderful host - responsive, kind, flexible - and the home was bright, airy, with gorgeous views. We couldn’t say enough good things about the wall of jasmine walking in. Thank you Lynae for having us in your home!

OB studio, ocean views, hot tub & garage parking!
Amazing stay at La casita !! Scott was an amazing host , had a binder of stuff to do locally and super attentive ! Will definitely be staying at La casita soon again

Law Street Retreat
Great, central location with everything we needed for a leaping off spot. Thanks!

Romantic Private Garden Studio Near Downtown
Kathi and Byron are great hosts and the place is beautiful, exactly as described. We had a great time, the place is very close to everything, there is a liquor store just 1 block away, very comfortable bed, beautiful garden 😃😃😃😃 Thank you very much Kathi, we hope to come back soon to San Diego and we will definitely book your place again.

Garden Cottage | 200Mbps | Sofabed | 55”TV | Patio
We had a great stay, the cottage was so cozy and felt right at home. The garden outside of the cottage was absolutely beautiful. Thank you again Donna for hosting us!

Central & Serene Secret Garden Guesthouse
We loved Susie’s garden guesthouse! Very walkable to a lot of lovely restaurants and close to SDSU!
Guest house rentals with a patio

Adorable cottage in Talmadge
The place was exactly as described. It was clean, peaceful and private. Their landscape was beautiful with all of the different flowers. Carlos was great with communication and a pleasure to interact with. He made things as simple and straightforward as possible. We would definitely stay at his lovely place again.

Free Bikes. 5 min walk to Windensea Beach La Jolla
We had a great stay at Carolina's property. The property looks exactly like the pictures (really cute and bright) and any amenity that you might need was provided. Carolina is quick to communicate and very helpful. We will definitely return!

Private 1 BR Paradise retreat
Jeanne and John's place was exactly as advertised in the description and photographs. The backyard and pool were beautiful unfortunately the weather and our schedule of events did not permit us time to indulge. If we ever needed a place in the area again we would definitely reserve another stay. We felt so welcomed and the extras were so thoughtful...like a balloon for my husband's birthday and a handwritten welcome letter. Thank you for the hospitality!

Sunset Cliffs Studio
Location was amazing, super close to the coast, restaurants, market, freeway. I loved spending time at Sunset Cliffs watching the surfers! Bed was comfy, and Mary was responsive, kind, and helpful. I was a single traveler, and felt like there was plenty of space for me. If you're not planning on spending too much time there, it could be doable with 2 adults, but tight. Note that the bathroom/shower area is not well lit, if you need that for safety reasons. Overall, I enjoyed my stay, and would consider this airbnb again in the future!

Downtown Cottage Minutes to Gaslamp & Petco Park
Great place to stay if you’re in town by yourself. Walkable to the convention center ~20 mins. Easy to get in and out of and quiet at night.

Cozy Urban Casita! Near Zoo, Gaslamp and Coronado
Absolutely the best! (And I'm a super-host too) Location, amenities, communication, just total thoughtfulness on Laurie's part made this the perfect San Diego getaway place for this retired active peaceful couple. If you have the privilege of staying here you'll feel like you came across magic.

SDSU Central Cozy Casita | Fast Wi-Fi | Walkable
I stayed from Monday and checked out on Friday morning. Nancy was accommodating, she worked with me in allowing both my son and I to check in early. Respectful and responded to my messages immediately. The area was good, never had a difficult time with parking. Street parking was available in front of the property which was convenient. Quiet area. The place was exactly what the pictures shows. I would definitely recommend and will rebook for my next trip to San Diego.

Charming Casita with City and Bay Views
Our hosts were extremely gracious, helpful and available. The casita was as advertised (clean and charming). The yard full of plants was very serene and charming. We would definitely stay here again!
Guest house rentals with a washing machine and dryer

Casita at the Cliffs
Amazing. Our host Libby was incredible, she made us feel very welcome. The place is wonderful, great location, clean, and stocked with everything we needed. Ocean Beach is a great find for those looking to for an SD beach location but are overwhelmed by the Mission and Pacific beach crowds.

Relaxing Oasis - short walk to shops & recreation
Super awesome location! Loved being able to walk to Balboa park and the Farmers Market!

Private Guest House for 2 with Kitchen + Laundry
The place was exactly as described! Paid for a place with far less amenities for the exact same price range so definitely recommend this one!

Beautiful Private Villa walk to beach
We loved staying at Kim’s villa, we were comfortable and very much at home. We slept well and loved the surroundings. Thank you Kim, will definitely be back!

Brand New Cozy Detached Casita w/AC & heat
A very nice place if you in PB with 2 off street parking spaces !!

Sea Star Cottage
Cottage was perfect for my daughter and I. Centrally located to all the sites we wanted to see. Every adventure was an easy drive. Place was in a nice, quiet neighborhood. Clean, comfortable, and pleasant.

Point Loma Oasis - Blocks From Sunset Cliffs
Great location, moments away from Sunset Cliffs and Ocean Beach. The unit was exceptional and easy to find . We were only there for one evening but it was peaceful and quiet and the entire area is beautiful. The communication from the host was on point . Highly recommend

Private San Diego Guest House - Beautiful View
This place lived up to all the other great reviews. It was very peaceful, felt like home away from home, quiet, private, clean. Close to shops and the highway and a good location for San Diego visitors. Easy parking. Laundry available. Everything you need to feel comfortable. Denelle is great at communicating and providing clear details. I would stay here again!
Quick stats about guest house rentals in Mission Bay, San Diego
Total rentals
20 properties
Nightly prices starting at
₹10,385 before taxes and fees
Total number of reviews
2.8K reviews
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wifi availability
20 properties include access to wifi
Popular amenities
Kitchen, Wifi and Pool
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- Rosarito Beach
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