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Guest house holiday rentals in Mission Bay, San Diego

Find and book unique guest house rentals on Airbnb

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Popular amenities for guest house rentals in Mission Bay, San Diego

Family-friendly guest house rentals

Guest favourite
Guest house in La Jolla
4.79 out of 5 average rating, 193 reviews

San Diego Shangri La

EricRating, 5 stars3 weeks ago
I really enjoyed staying here. It's on a canyon, which provided a great view and a nice breeze and was very quiet. We had our little dog with us and he loved being able to explore the yard. It's a great location in La Jolla / North PB. It's at the top of my list for my next trip to San Diego.
Top guest favourite
Guest house in Hillcrest
4.98 out of 5 average rating, 167 reviews

Hidden Casita with Private Deck & Patio

KarenRating, 5 stars2 days ago
Charming Airbnb in a very quiet neighborhood. Great communication from the hosts and nice treats and a bottle of wine to welcome us. Street parking was a little tight, but we always found a convenient space nearby. Would definitely stay there again.
Top guest favourite
Guest house in Greater North Park
4.97 out of 5 average rating, 186 reviews

New Guest House - North Park

KrystenRating, 5 stars3 weeks ago
Lynae’s place was wonderful, as was Lynae! Balboa park right nearby, with gorgeous trails and scenery. Walkable to North Park area which had a fun variety of bars, shops, and restaurants. Lynae was a wonderful host - responsive, kind, flexible - and the home was bright, airy, with gorgeous views. We couldn’t say enough good things about the wall of jasmine walking in. Thank you Lynae for having us in your home!
Guest favourite
Guest house in La Jolla
4.93 out of 5 average rating, 572 reviews

Modern Surf Cottage

SydneyRating, 5 stars1 week ago
We absolutely loved staying here! The place is so cute & cozy. If we find ourselves back in San Diego we will definitely be booking this place.
Guest favourite
Guest house in Point Loma Peninsula
4.93 out of 5 average rating, 659 reviews

OB studio, ocean views, hot tub & garage parking!

JesseRating, 5 stars1 month ago
Amazing stay at La casita !! Scott was an amazing host , had a binder of stuff to do locally and super attentive ! Will definitely be staying at La casita soon again
Guest favourite
Guest house in City Heights
4.95 out of 5 average rating, 150 reviews

Cozy Cottage 1/2 mile to North Park close to dtwn

JasonRating, 5 stars2 weeks ago
Excellent place. We loved the location relative to the sites we wanted to see. Free parking, laundry, very well stocked kitchen, comfortable bed. We were very comfortable and happy here. And as a host Wendy was phenomenal. One of the most responsive hosts I’ve had the pleasure of connecting with on Airbnb. Thank you Wendy!!!
Top guest favourite
Guest house in Sherman Heights
4.96 out of 5 average rating, 533 reviews

Romantic Private Garden Studio Near Downtown

HéctorRating, 5 stars3 weeks ago
Kathi and Byron are great hosts and the place is beautiful, exactly as described. We had a great time, the place is very close to everything, there is a liquor store just 1 block away, very comfortable bed, beautiful garden 😃😃😃😃 Thank you very much Kathi, we hope to come back soon to San Diego and we will definitely book your place again.
Superhost
Guest house in Pacific Beach
4.78 out of 5 average rating, 393 reviews

Law Street Retreat

HilaryRating, 5 stars2 weeks ago
Great, central location with everything we needed for a leaping off spot. Thanks!

Guest house rentals with a patio

Top guest favourite
Guest house in Talmadge
4.99 out of 5 average rating, 208 reviews

Adorable cottage in Talmadge

NysaRating, 5 stars1 week ago
The place was exactly as described. It was clean, peaceful and private. Their landscape was beautiful with all of the different flowers. Carlos was great with communication and a pleasure to interact with. He made things as simple and straightforward as possible. We would definitely stay at his lovely place again.
Top guest favourite
Guest house in La Jolla
4.97 out of 5 average rating, 117 reviews

Free Bikes. 5 min walk to Windensea Beach La Jolla

ChristinaRating, 5 stars6 days ago
We had a great stay at Carolina's property. The property looks exactly like the pictures (really cute and bright) and any amenity that you might need was provided. Carolina is quick to communicate and very helpful. We will definitely return!
Top guest favourite
Guest house in La Mesa
4.99 out of 5 average rating, 115 reviews

Private 1 BR Paradise retreat

AlleshaRating, 5 stars1 week ago
Jeanne and John's place was exactly as advertised in the description and photographs. The backyard and pool were beautiful unfortunately the weather and our schedule of events did not permit us time to indulge. If we ever needed a place in the area again we would definitely reserve another stay. We felt so welcomed and the extras were so thoughtful...like a balloon for my husband's birthday and a handwritten welcome letter. Thank you for the hospitality!
Guest favourite
Guest house in Point Loma Peninsula
4.94 out of 5 average rating, 126 reviews

Sunset Cliffs Studio

KatieRating, 5 stars2 weeks ago
Location was amazing, super close to the coast, restaurants, market, freeway. I loved spending time at Sunset Cliffs watching the surfers! Bed was comfy, and Mary was responsive, kind, and helpful. I was a single traveler, and felt like there was plenty of space for me. If you're not planning on spending too much time there, it could be doable with 2 adults, but tight. Note that the bathroom/shower area is not well lit, if you need that for safety reasons. Overall, I enjoyed my stay, and would consider this airbnb again in the future!
Top guest favourite
Guest house in San Diego
5 out of 5 average rating, 108 reviews

SDSU Central Cozy Casita | Fast Wi-Fi | Walkable

DianneRating, 5 stars6 days ago
I stayed from Monday and checked out on Friday morning. Nancy was accommodating, she worked with me in allowing both my son and I to check in early. Respectful and responded to my messages immediately. The area was good, never had a difficult time with parking. Street parking was available in front of the property which was convenient. Quiet area. The place was exactly what the pictures shows. I would definitely recommend and will rebook for my next trip to San Diego.
Top guest favourite
Guest house in Point Loma Peninsula
4.93 out of 5 average rating, 116 reviews

Charming Casita with City and Bay Views

LenoreRating, 5 stars4 days ago
Our hosts were extremely gracious, helpful and available. The casita was as advertised (clean and charming). The yard full of plants was very serene and charming. We would definitely stay here again!
Guest favourite
Guest house in Serra Mesa
4.95 out of 5 average rating, 106 reviews

Cozy, Quiet and Private Backyard Studio Escape

JoeeRating, 5 stars2 weeks ago
I had an absolutely wonderful stay at Stephanie's place! The space was spotless and made me feel right at home. The location was fantastic and the check-in process was incredibly easy. Stephanie was an outstanding host, always quick to respond to any questions. I especially loved the rain shower! I highly recommend this Airbnb to anyone visiting San Diego and would definitely love to stay here again!
Superhost
Guest house in City Heights
4.86 out of 5 average rating, 265 reviews

Heart of SD | Zoo Nearby | Private Patio | Central

LaylaRating, 5 stars1 week ago
This is a nice little private spot you can be at right by Balboa Park. Close to Downtown, and the host was great and very responsive. I believe the washer and dryer is a plus! One thing I loved is Hulu is set up on the TV so that was really nice!

Guest house rentals with a washing machine and dryer

Guest favourite
Guest house in Ocean Beach
4.96 out of 5 average rating, 288 reviews

Private beach guesthouse w/ private parking

KcRating, 5 stars1 week ago
This was my second time staying here and it was—once again—perfect! The location is amazing, the size is wonderful, and I loved all of the amenities.
Top guest favourite
Guest house in Point Loma Peninsula
4.98 out of 5 average rating, 103 reviews

Casita at the Cliffs

J. DominicRating, 5 stars3 days ago
Amazing. Our host Libby was incredible, she made us feel very welcome. The place is wonderful, great location, clean, and stocked with everything we needed. Ocean Beach is a great find for those looking to for an SD beach location but are overwhelmed by the Mission and Pacific beach crowds.
Guest favourite
Guest house in City Heights
4.98 out of 5 average rating, 135 reviews

Private Guest House for 2 with Kitchen + Laundry

ArleneRating, 5 stars1 month ago
The place was exactly as described! Paid for a place with far less amenities for the exact same price range so definitely recommend this one!
Superhost
Guest house in Pacific Beach
4.92 out of 5 average rating, 200 reviews

Brand New Cozy Detached Casita w/AC & heat

Maria & AndrewRating, 5 stars1 week ago
A very nice place if you in PB with 2 off street parking spaces !!
Top guest favourite
Guest house in Greater North Park
4.99 out of 5 average rating, 163 reviews

Carrie’s North Park Casita, in Heart of San Diego

JaneRating, 5 stars1 month ago
Carrie's Casita was perfect for the two of us. A private little courtyard with lemon and orange trees and the scent of jasmine was very welcoming! The studio-style space was very comfortable and well-appointed. We took advantage of the outdoor seating for downtime after busy mornings of sightseeing. The walkable neighborhood has many architecturally interesting, historic homes with amazing front gardens filled with succulents and cacti of all shapes and sizes. The location is great for accessing great restaurants and boutiques. We would love to visit again!
Guest favourite
Guest house in Pacific Beach
4.85 out of 5 average rating, 246 reviews

Sea Star Cottage

AmyRating, 5 starstoday
This place was super cute and a good location. Unfortunately, we had hot water issues. However, Jeff was quick to respond and check it out. He also, offered us a refund since the water couldn't be fixed during our stay and we chose to leave early. We highly recommend Jeff as a host and this cute cottage
Guest favourite
Guest house in San Diego
4.93 out of 5 average rating, 150 reviews

Clean Cozy Private Guesthouse - Central San Diego

MoniqueRating, 5 stars1 week ago
This airbnb was very nice for two people. It was a perfect space with a spot on the driveway for one car. Walking in, the airbnb was clean and smelled really good. There was plenty of amenities and our host Frank was friendly and responsive. We would book again!
Guest favourite
Guest house in Point Loma Peninsula
4.87 out of 5 average rating, 100 reviews

Point Loma Oasis - Blocks From Sunset Cliffs

StephenRating, 5 stars3 days ago
Great location, moments away from Sunset Cliffs and Ocean Beach. The unit was exceptional and easy to find . We were only there for one evening but it was peaceful and quiet and the entire area is beautiful. The communication from the host was on point . Highly recommend

Quick stats about guest house rentals in Mission Bay, San Diego

  • Total rentals

    20 properties

  • Nightly prices starting at

    ₹10,413 before taxes and fees

  • Total number of reviews

    2.8K reviews

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wifi availability

    20 properties include access to wifi

  • Popular amenities

    Kitchen, Wifi and Pool

Destinations to explore