Guest house holiday rentals in La Mesa
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Top-rated guest house rentals in La Mesa
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in La Mesa
Family-friendly guest house rentals
Guest house in La Mesa
4.74 out of 5 average rating, 218 reviewsSan Diego/Mt. Helix Two Bedroom
30 Sep – 7 Oct
Guest house in San Diego
4.97 out of 5 average rating, 506 reviewsCentral & Serene Secret Garden Guesthouse
15–22 Oct
Guest house in San Diego
4.97 out of 5 average rating, 291 reviewsPrivate Guest House with a View
6–13 Aug
Guest house in San Diego
4.99 out of 5 average rating, 364 reviews*Private Canyon Retreat: Your Own Guesthouse*
7–14 Oct
Guest house in San Diego
4.96 out of 5 average rating, 251 reviewsYour Kensington Bungalow
10–17 Sep
Guest house in San Diego
4.93 out of 5 average rating, 447 reviewsPrivate Cottage in Walkable North Park w/AC
25 May – 1 Jun
Guest house in Chula Vista
4.95 out of 5 average rating, 475 reviewsPrivate Casita in Great Eastlake Neighborhood
24 Sep – 1 Oct
Guest house in San Diego
4.96 out of 5 average rating, 211 reviewsNorth Park, San Diego's Best At Your Doorstep
3–10 Jun
Guest house rentals with a patio
Guest house in San Diego
4.99 out of 5 average rating, 151 reviewsAdorable cottage in Talmadge
15–22 Apr
Guest house in San Diego
4.93 out of 5 average rating, 122 reviewsModern Guest House with pool, steps to SDSU
2–9 Sep
Guest house in La Mesa
4.97 out of 5 average rating, 117 reviewsSan Diego Newly Built Private Guesthouse (Sleep 5)
7–14 Jul
Guest house in San Diego
4.99 out of 5 average rating, 107 reviewsModern Guest House with Patio, Parking, & Laundry
1–8 Aug
Guest house in San Diego
4.93 out of 5 average rating, 147 reviewsCentral studio w/ private outdoor space & parking
13–20 Jan
Guest house in San Diego
4.98 out of 5 average rating, 123 reviewsPrivate Studio Cottage with Outdoor Patio
11–18 Dec
Guest house in San Diego
4.85 out of 5 average rating, 124 reviewsPrivate, beautiful 1-bedroom 2 story guest house
27 Jun – 4 Jul
Guest house in Spring Valley
4.97 out of 5 average rating, 111 reviewsLoft Cabin-Night Cinema+Hot Soaking Tub+Views!
19–26 Jun
Guest house rentals with a washing machine and dryer
Guest house in San Diego
4.96 out of 5 average rating, 117 reviews1BR Casita in the Heart of Kensington!
3–10 Sep
Guest house in Lemon Grove
4.9 out of 5 average rating, 162 reviews"Glam Farmhouse dream cottage"🏠🌠
13–20 Oct
Guest house in El Cajon
4.99 out of 5 average rating, 152 reviewsModern mountain guest house. Incredible views
14–21 Aug
Guest house in San Diego
4.95 out of 5 average rating, 107 reviewsRelax in a Centrally Located, Modern Guest House
13–20 Dec
Guest house in San Diego
4.98 out of 5 average rating, 185 reviewsNorth Park Garden Retreat Casita
5–12 Sep
Guest house in San Diego
4.98 out of 5 average rating, 205 reviewsOur Garden Cottage: A home away from home.
1–8 Jan
Guest house in San Diego
4.84 out of 5 average rating, 213 reviewsCozy Cottage
8–15 Jun
Guest house in San Diego
4.96 out of 5 average rating, 455 reviewsStorybook house private Studio
18–25 Sep
Quick stats about guest house rentals in La Mesa
Total rentals
60 properties
Wifi availability
60 properties include access to wifi
Rentals with dedicated workspaces
30 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Total number of reviews
3.9T reviews
Nightly prices starting at
₹4,170 before taxes and fees
Destinations to explore
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