House holiday rentals in La Mesa
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Top-rated house rentals in La Mesa
Guests agree: these houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for house rentals in La Mesa
House rentals with a pool
Home in La Mesa
4.93 out of 5 average rating, 106 reviewsUpdated TownHome, Great Location, Fantastic Views
16–23 Apr
Home in La Mesa
4.87 out of 5 average rating, 130 reviewsThe Queen House
7–14 Sep
Home in La Mesa
4.99 out of 5 average rating, 127 reviewsMid-Century Style Family House with Spa
7–14 Jun
Home in La Mesa
4.96 out of 5 average rating, 137 reviewsHeated pool, outdoor fire pits, chef's kitchen
30 Jul – 6 Aug
Home in El Cajon
4.97 out of 5 average rating, 134 reviewsBeautiful 3,000 Sq Ft Tropical Oasis
22–29 Sep
Home in La Mesa
4.81 out of 5 average rating, 131 reviewsSunny SD/La Mesa Updated '24-Pool-4 bed-Sleeps 10
11–18 Oct
Home in San Diego
4.9 out of 5 average rating, 116 reviewsSan Diego Getaway W/Pool & Hot tub! Sleeps 8!
28 Sep – 5 Oct
Home in San Diego
5.0 out of 5 average rating, 138 reviewsMidcentury Lux 4BR home with Pool, Spa & Cabana
1–8 Nov
Weekly house rentals
Home in San Diego
4.96 out of 5 average rating, 108 reviewsBeautiful new 1 bedroom house
4–11 Jan
Home in San Diego
4.91 out of 5 average rating, 157 reviewsHawk's nest - wakeup to nature - Hillcrest
25 Nov – 2 Dec
Home in San Diego
4.88 out of 5 average rating, 153 reviewsPrivate cottage walkable to restaurants and bars
11–18 Oct
Home in San Diego
4.91 out of 5 average rating, 159 reviewsCute Small House
30 Sep – 7 Oct
Home in San Diego
4.94 out of 5 average rating, 133 reviewsDesirable North Kensington+Quiet+Allergen Free
16–23 Jul
Home in San Diego
4.87 out of 5 average rating, 137 reviewsMarta's house, San Diego, Close Downtown, Garden
14–21 Oct
Home in San Diego
4.97 out of 5 average rating, 259 reviewsFun & Funky TINY House for 2 North Prk/Hillcrest
6–13 Sep
Home in San Diego
4.9 out of 5 average rating, 363 reviewsComfy 2Br Craftsman House in the Heart of SD
16–23 Mar
Private house rentals
Home in La Mesa
4.83 out of 5 average rating, 119 reviewsLa Mesa's Tranquility
18–25 Aug
Home in San Diego
4.9 out of 5 average rating, 101 reviewsCozy 2Bed-Private Parking, Dog Friendly, Big Yard!
16–23 Oct
Home in Bonita
5.0 out of 5 average rating, 155 reviewsMulberry House..convenient to San Diego and Mexico
11–18 Jun
Home in La Mesa
4.95 out of 5 average rating, 111 reviewsCheery & Roomy Family Home w/Master Suite, Fence
9–16 Mar
Home in La Mesa
4.96 out of 5 average rating, 52 reviewsCozy, Single Bedroom, Detached Guest House
30 Aug – 6 Sep
Home in El Cajon
5.0 out of 5 average rating, 7 reviewsCozy 1BR Home with Lovely Front Yard
23–30 Nov
Home in La Mesa
4.97 out of 5 average rating, 35 reviewsGarden Studio (40% long, 15% short term discount!)
29 Jan – 5 Feb
Home in El Cajon
4.98 out of 5 average rating, 88 reviewsSuite Charles Way: A Cozy Fletcher Hills Studio
10–17 Aug
Quick stats about house rentals in La Mesa
Total rentals
280 properties
Rentals with dedicated workspaces
170 properties have a dedicated workspace
Rentals with a pool
80 properties have a pool
Pet-friendly rentals
90 properties allow pets
Family-friendly rentals
190 properties are a good fit for families
Total number of reviews
9.5T reviews
Destinations to explore
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