
House holiday rentals in La Mesa
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Top-rated house rentals in La Mesa
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House rentals with a pool

3 BR Urban Oasis with Pool and Spa in Great Area
I am a San Diego local, but my family was coming to town and we needed more space. I picked this place because I knew my sister and brother-in-law would love being able to walk to all the restaurants and brewery nearby and my 6 year old nephew would get a lot of use out of the pool. The place exceeded my expectations, it was perfect for everyone. We spent a lot of time in the backyard swimming or playing board games, and my Mom got a lot of use out of the hot tub. Communication with the host was excellent and the place was comfortable and clean. The only downside is my family might visit too often now!

La Jolla Beach House-Family Focused-3min to Beach
We had a fantastic week in La Jolla! John’s place was charming, spotless, and perfect for our family. The home was well-stocked with thoughtful amenities—including beach gear—and had everything we needed to feel comfortable. The location is unbeatable: a quiet, family-friendly neighborhood within a few minutes walking distance to the beach, great restaurants, coffee shops, and more. John was a friendly and responsive host who made everything easy from start to finish. Honestly could not have asked for a better host. Highly recommend for families looking for a relaxing, convenient stay in La Jolla. We’d love to come back!

Your Modern Lux Pool Resort in the Heart of SD
Stay at Katri’s was great. Had delicious cookies waiting for us when we checked in, which was a breeze. House was spacious and entire lot was very big. Pool was great and even after we had told them that no heated pool would be necessary, Mother Nature had a different idea and gave us some more than unexpected chilly weather, so they had no problem throwing the heater on for us. Freeway in the background was hardly a noise problem for us personally. Just far enough that it didn’t affect us, and was nice to see what our morning commute was going to be like. Brought two dogs with the group that absolutely loved everything (after one of them finally got over his fear of the staircase). All in all a great stay in a great neighborhood. Cant comment more how quickly they responded to us in the days leading up to the trip, and while we were there. Great hosts!

Lionhead - Private Boutique Home
Quiet location, exactly as pictured and described. Parking could be a challenge if you have a large vehicle but being able to park in the garage made it easier. Great communication!

Bright and spacious home with views, pool & spa.
Nice place to stay in the San Diego area. Conveniently located within reasonable driving distance to popular attractions and nestled in a quiet, peaceful neighborhood. The backyard and pool are beautiful. The pool was by far the highlight of our stay. Miguel is an exceptional host: responsive, accommodating, and a pleasure to communicate with.

University Heights Oasis Getaway
Exactly as the other reviewers have described, it is just a beautiful oasis in a perfect quiet neighborhood. Don’t wait, book now!

Oasis with ocean views/Pool/Hot tub! Sleeps 10!
Van was very friendly, even had great food recommendations for my family and I. The home was one of the best Airbnbs I’ve ever stayed in. My children thought we were in a place of royalty with how well put together the house was. Loved our stay and will definitely be back

Canyon House: Sunset View Tranquil Private Pool
Jessica’s home is beautiful and located in a lovely neighborhood that is close proximity to many things. We came to celebrate the graduation of my niece and Jessica’s home was a great place for the family to connect, rest between events and spend time together! Her home is beautifully appointed and was perfect for our stay. Jessica is a great host who communicates with her guests and is very responsive! Her home is filled with good energy and I would definitely book again! for future family events when visiting San Diego!
Weekly house rentals

Cozy 1BR Home with Lovely Front Yard
This place is so cute! It was close to everything AC works great. The bed was super comfy and the massage chair was a huge bonus! Will be going back if available next time I’m in town! Ty

Exquisite, Modern, Walk to Bliss
Perfect! Derek and Brooke really have such a wonderful place and it’s so close to a very eventful downtown La Mesa. We dined there each night and attended the local Farmer’s markets. The home is so peaceful and had everything we needed. It’s just enough space for 2 - 4 people. (This trip was only me and my mom) They gave ample instructions and it was very easy to lock up when we left and easy to enter. We also appreciated being able to park directly in front of the unit on the street. The neighborhood is so lovely, you’ll wish you lived on this street! I’m definitely going to rebook this space next time I’m in town.

Sunny Loft | Beaches | Lakes | Trails
We live in San Diego and needed space while we completed work on our place. We could easily rent a hotel but prefer not to. Alejandro’s place is in a nice neighborhood and we always wanted to see what it was like to live in a loft. It’s definitely not for us but we’re glad we experienced it. Alejandro’s loft is top of the line with great decor and nice touches. We do cook a lot and and there were not enough pots but it wasn’t a big deal. There was plenty of coffee, lavender tea (very yummy), plenty of cooking space and overall a really nice stay. I would not recommend a loft for someone that is frail as you do have to climb a ladder to bed and you have to be careful climbing down. Alejandro and Magdalena are responsive and attentive and vey welcoming yet not intrusive.

Cozy quiet getaway, great mattress (1-br)
Loved this cute and cozy little place. Bed was very comfortable nice neighborhood and very pet friendly

Modern, Private, & Stylish Home
Great place, very easy to navigate to! House is very spacious and beautiful! Longevity Living ensured we were satisfied from start to finish!

Cozy Getaway | SDSU | Firepit & Private Yard
We were in San Diego for medical appointments for my wife, and this was a peaceful oasis. Very clean and quiet. Great value for the price.

Charming Cozy Studio Centrally Located
I loved staying here. The space was cozy and very clean. Nina was immensely responsive when I had a question. I felt very safe here as a solo traveler.

Luxury Hilltop Stay: Pool, Firepit & Views
My family had a great time at Mark’s home. We highly recommend! Would love to come back again.
Private house rentals

[1,888 SF] Casa De Rosas: Spacious home near SDSU
My family came to town for me ur grandfathers funeral and even though we were there for a funeral we all had a great time during our stay. A huge thank you for being so accommodating. We all enjoyed your home, thanks for creating such a great home away from home.

Cozy, cute home: Welcome to Hilltop Sanctuary
Sarah’s place was clean and comfortable. Easy check in. Host was on top of everything which made it smooth. Definitely worth the money spent. Highly recommended!!!

The Pool House
The place was really nice, and the owners were very easy to work with. The place was really nice, and the owners were very easy to work with. We felt very comfortable in the home. There were a few small issues — when we moved the sofa bed, we found quite a bit of trash underneath, as well as under other furniture and behind trash cans. I have small children and wanted to make sure nothing was left behind, so it was noticeable during our quick check. Other than that, everything was peWe felt very comfortable in the home. There were a few small issues — when we moved the sofa bed, we found quite a bit of trash underneath, as well as under other furniture and behind trash cans. I have small children and wanted to make sure nothing was left behind, so it was noticeable during our quick check. Other than that, everything was perfect! I would absolutely love to reserve this Airbnb again on our next visit to San Diego. We’re originally from San Diego and travel back often to visit family.

Lavish pool Villa In Mt. Helix, close to beaches
We stayed at Zeina and Mo's place for one week with our East Coast and West Coast children and grands--6 adults and 6 children in all from ages 2-12. We could not have been more pleased. The house was meticulously clean and was spacious enough for all. The kitchen was well stocked with all we needed to prepare meals at home. An added plus was an outdoor grill under a cabana like space with a table for 6 and outdoor counter to provide additional seating. The pool is larger than it appears in the pictures on the web site. The whole outdoor space was clean and welcoming and proved to be a center piece of our stay. There were plentiful and soft towels for bathing and the pool. Zeina and Mo were promptly responsive to any questions or concerns we had. We left with many fond memories of our week together, in large part due to to how comfortable and pleasant we felt about our stay was at Zeina and Mo's house.

SunnySD Private Pool-SoCal Oasis
Kaios place was perfect for our event. Not a thing I would change about this place. Great donut shops, coffee spots, ceviche spots as stones throw away. Peaceful, quiet, stress free place.

Sunnyside Resort Spa, Beach, Zoo, Arcade
Chris was very professional and went to the full extent to make sure my family and I had everything we needed for our comfort. I highly recommend staying here if you want a home that gives off comfortable vibes and has so many options for fun especially with kids. Will stay again when I’m back in the area.

Hilltop luxe retreat with breathtaking views
Lovely home and view. Everything as described!

Tropical Oasis: spa, solar heated pool, waterslide
This place was amazing and is possibly the best among the AirBnb's I have stayed in. My group had a lot of fun, especially with the water slide.
Quick stats about house rentals in La Mesa
Total rentals
290 properties
Total number of reviews
12K reviews
Family-friendly rentals
180 properties are a good fit for families
Pet-friendly rentals
90 properties allow pets
Rentals with a pool
70 properties have a pool
Rentals with dedicated workspaces
170 properties have a dedicated workspace
Destinations to explore
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- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Tijuana Beach
- Pacific Beach
- Coronado Beach
- La Misión Beach
- SeaWorld San Diego
- Coronado Shores Beach
- Oceanside Harbor
- University of California San Diego
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- Black's Beach
- San Diego Zoo Safari Park
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- Belmont Park
- Pechanga Resort Casino
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- Sesame Place San Diego
- Playas Los Buenos
- Playa Popotla
- USS Midway Museum
- Torrey Pines Golf Course