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Holiday rentals with lake access in Pickens County

Find and book unique lake access rentals on Airbnb

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Popular amenities for lake access rentals in Pickens County

Lake access house rentals

Top guest favourite
Home in Pickens
5 out of 5 average rating, 51 reviews

Tekoa at Table Rock

KevinRating, 5 stars1 month ago
Layne was so helpful. She was great to work with. Her place was really great - comfortable with gorgeous views!
Guest favourite
Home in Seneca
4.92 out of 5 average rating, 37 reviews

Lakefront Mid-Century Dream Home / 3 mi to Clemson

SusanRating, 5 stars3 weeks ago
We had a lovely stay in Lauren's home. You feel like you're living in the Brady Bunch house! Classic 1960s everything. The beds and seating were all very comfortable, and we enjoyed the abundant decks, the hammock, the kayak, the TV... the kitchen had everything you could want, and we appreciated the extra bag of ice and cans of sparkling water they left for us. We highly recommend it. If you're more noise-sensitive, we recommend the downstairs bedroom, which is insulated from the noisier/brighter open layout of the upstairs.
Top guest favourite
Home in Seneca
4.99 out of 5 average rating, 193 reviews

Lakeside @ Lake Hartwell in Clemson, SC 🐟🌅🚤

MickeyRating, 5 stars1 month ago
Can’t say enough great things about the location and the host. Property exceeded all our expectations for a great Easter weekend with our family. Highly recommend to anyone looking for a lake get away close to Clemson and Seneca
Guest favourite
Home in Easley
4.91 out of 5 average rating, 23 reviews

Emerald Shore

MichelleRating, 5 stars2 weeks ago
My husband and I loved our stay here and this will definitely be our “go to” place when we visit the area again! We rented Nancy’s home for an extended weekend to attend our daughter’s graduation and to celebrate our wedding anniversary. We arrived and checked ourselves in with clear, simple instructions. We were pleasantly surprised with a cake and a very thoughtful card from Nancy congratulating not only us but our graduate as well. The home was well stocked with starter supplies and even some snacks. We absolutely loved the bed and both slept comfortably each night! We grabbed dinner from Dacusville Pizza Stop our first night there since we’d had a long day of traveling and it did not disappoint. Also enjoyed unwinding on the back deck and just relaxing in the peace and quiet!
Top guest favourite
Home in Salem
5 out of 5 average rating, 28 reviews

Golf view, lake access, 3 pools!

StephanieRating, 5 stars2 weeks ago
We had a wonderful stay at the Sail Loft over Memorial Day weekend! From the moment we arrived, we felt right at home. The space is so cozy, beautifully decorated, and full of thoughtful touches—it’s clear that every detail has been carefully considered. It’s just like the photos, only better in person! Nichole was the perfect host—kind, responsive, and welcoming. She guided us throughout our stay, making sure everything went smoothly and that we felt comfortable and cared for. We loved enjoying the Keowee Key amenities, especially the pool and dining at the club’s restaurants. It truly felt like a hidden gem! We’re already looking forward to coming back soon. Highly recommended for anyone looking for a peaceful retreat with all the comforts of home!
Top guest favourite
Home in Greenville
5 out of 5 average rating, 25 reviews

Sunset Cottage -Waterfront with Kayaks

VanessaRating, 5 stars1 week ago
Vickie was the best host I ever have. She had great recommendations all the time.
Guest favourite
Home in Salem
4.98 out of 5 average rating, 44 reviews

Cantrell Point Cottage on Keowee

JaneRating, 5 stars1 month ago
This deep water front cottage is absolutely magic. Adorably decorated and rare location on north end. Crystal clear water and several great new restaurants. We will make it our summer rental
Top guest favourite
Home in Seneca
4.95 out of 5 average rating, 175 reviews

Private lake setting close to Clemson University

ThomasRating, 5 stars1 month ago
To our super hosts: Keith and Jenifer, Thanks for providing such a warm and welcoming place to stay! It felt like a perfect home away from home. The location is incredibly convenient to all areas! There aren’t enough superlatives to describe all the marvelous things about this lovely home. Everything was well stocked in the kitchen , which was neatly organized and plenty of nice towels, linens, blankets in the baths and bedrooms! The home was immaculate and very well appointed. Keith is a great communicator and we can’t wait to come back to relax, recharge and enjoy! Thanking you over and over for everything, especially the little extra touches, and the delicious extra treats that my husband was over the moon for❣️😁

Apartment rentals with lake access

Flat in Seneca
4.8 out of 5 average rating, 5 reviews

Lakeside Clemson apartment

CeilRating, 5 stars2 months ago
Wonderful stay. It was very quiet. The location was perfect. Condo was clean and comfortable. I asked for a last minute change and Dorian was very gracious with accommodating me. I will stay there again!
Superhost
Flat in Sunset
4.74 out of 5 average rating, 19 reviews

"Greenbrier" Home in the Joccassee Wilderness

AprilRating, 5 stars1 month ago
My family and I absolutely enjoyed our little getaway here. The first night we woke up to it being over 85 degrees in the home but Tami was quick to respond and immediately had two window A/C units placed in the home to keep it cool. We are already talking about our next adventure and staying at this location again! Thank you Tami for allowing my family to celebrate the Easter holiday here!
Top guest favourite
Flat in Six Mile
5 out of 5 average rating, 22 reviews

Condo and Lake Keowee

DonnaRating, 5 stars1 week ago
The condo was beautifully decorated and well equipped. We loved the peaceful location. Craig checked in to see how things were going. We loved this listing so much we reserved it for our next visit to SC
Flat in Salem

Beautiful Lake Keowee Condo

BethRating, 5 stars13 months ago
Will stay again soon.
Flat in Seneca
4.67 out of 5 average rating, 3 reviews

Apartment in Seneca

TommyRating, 5 stars7 months ago
Great location. The place is really decorated well, and Stuart made the stay seem personal, not like a hotel experience.
Flat in Clemson
4.86 out of 5 average rating, 21 reviews

Modern Pool Retreat Near SC Botanical Gardens

DanaRating, 5 stars1 month ago
We stay in Clemson multiple times a year and this was our first time staying at Dockside…and we LOVED it. So much space for our family. Beautiful views. Amenities galore. Parking was easy. Gym was amazing. Very quiet. Convenient to Campus! Will stay here again and again!
Flat in Seneca

Gameday Getaway on Lake Hartwell - close to campus

JillRating, 5 stars8 months ago
Amelia is a super host! She was always responsive, before and during our stay with clear communication about everything. She provided flexibility on check-in and check-out. The condo is about a 5 minute drive to Clemson's campus, which made it the perfect location for us to visit our son there and attend a football game. It was exactly as described/ pictured, squeaky clean, nicely updated, and quiet (on the 3rd floor). It is located in an older complex, but inside the condo has been completely updated with brand new flooring, bathrooms, countertops, appliances, etc. TVs are in every room, but you will probably not want to stay inside much....it's on the lake! We didn't get down to the lake, but we could see the lake from the balcony of the condo. Parking was always available all weekend, directly in front. Everything we could have possibly needed was there, and it was in places we would expect to find it! We are already picking dates to go back to this AirBNB! Thank you, Amelia!
Top guest favourite
Flat in Seneca
5 out of 5 average rating, 24 reviews

3BR Ground floor condo - 2.4 Miles to Death Valley

SueRating, 5 stars1 month ago
We were extremely pleased the moment we walked into the unit. Beautiful inside, room for everyone, kitchen had everything we needed to cook, super quiet and peaceful. The coffee bar and water fridge was stocked, assorted munchie basket and the quality bathroom towels were the added touches that a lot of previous Airbnbs have missed. The hosts were kind and proactive and we did not need one thing. My adult kids sat down for chess and that was the bonding time we’ve been wanting to have. The patio/balcony provided the best coffee and cocktail time. My favorite place 💜🧡 GO TIGERS

Lake access cottage rentals

Cottage in Salem
4.75 out of 5 average rating, 32 reviews

Lake Front Cottage/Floating Dock

MadisonRating, 5 stars3 weeks ago
Lara's place was the perfect get away for the weekend. The location on the lake is perfect right by a boat ramp and a close boat ride to the waterfall on Keowee. The house was so cozy and comfortable and I loved the privacy. I will absolutely be sharing this spot and book again soon!
Guest favourite
Cottage in Sunset
4.95 out of 5 average rating, 114 reviews

River Cottage Nature Privacy

BrandiRating, 5 stars3 weeks ago
I stayed here a week for work. It was the perfect place to come home to every night. I did get to visit Lake Jocassee and Twin Falls on my last day--highly recommend! Matt was great, and the charming little cabin was a peaceful retreat in a gorgeous location! It had everything I needed--even things I didn't know I would need (like poison ivy soap to use as a precaution after I'd been romping around in the wilderness for work)! I'd definitely come back here, whether I'm in the area for work or play.
Guest favourite
Cottage in Easley
4.93 out of 5 average rating, 68 reviews

Cozy Cottage on the lake

DonnaRating, 5 stars11 months ago
We had a wonderful stay at the cottage. We loved the pool and the grankids loved it too. The cottage was clean , comfy, and cozy. The cottage was very peaceful and private, located on a dead end road. We highly recommend a stay . Will book again.
Cottage in Salem
4.82 out of 5 average rating, 62 reviews

Jocassee Landing Lake Cottage - 1 mi to Boat Ramp!

BrooklynRating, 5 stars3 weeks ago
It’s was a beautiful place, very clean and close to the lake. Over all it was a great get away, very little traffic and so quiet. We had a great time would definitely stay again!!
Top guest favourite
Cottage in Six Mile
4.99 out of 5 average rating, 196 reviews

Lake Keowee Waterfront Cottage - Private Retreat

PaulRating, 5 stars1 week ago
Pine island point does not disappoint. canceled a future beach trip and booked a second trip to visit here again before the first trip was even completed. Great place to stay, amazing surroundings, and genuinely hospitable hosts.
Top guest favourite
Cottage in Pickens
4.98 out of 5 average rating, 60 reviews

At Table Rock+ Private Trail+Fire Pit+King Bed+BBQ

AliedaRating, 5 stars2 weeks ago
We had a fantastic stay near Table Rock, SC. The place was spacious, spotless, and we had full access to the entire property. Outdoor spaces were a real highlight—beautiful lights at night and plenty of room to relax. The hike up Table Rock Trail was no joke—definitely a challenge—but absolutely worth the effort for the views. The private footpath to the trailhead was super convenient, with sturdy steps and gorgeous foliage all around: holly, mountain laurel, rhododendron, even raspberry bushes. Inside, the coffee bar had just the right variety, and the stove/cookware setup was top-notch—everything cooked evenly, which is a rare win in a rental. The packs and snacks were a thoughtful touch, and having a park pass included saved us time and money. BT was responsive and got us checked in a few minutes early with no hassle. Bonus points for the covered carport—it came in clutch during a light rain. We’ll definitely be back. Highly recommend.

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