House holiday rentals in Pickens County

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Popular amenities for house rentals in Pickens County

House rentals with a pool

Home in Pendleton
4.67 out of 5 average rating, 18 reviews

The Hawks Nest

BridgetRating, 5 stars9 months ago
Exactly what I was looking for! I was in-town for parent's weekend and looking for a place with a great kitchen to prepare home cooked meals for my daughters as well as great location. Instantly felt like home and we knew an amazing family lived there. The host went out of her way to make sure we were comfortable and had everything we expected. I hope it is available for my future trips!!
Home in Salem
5 out of 5 average rating, 14 reviews

Lakefront, Dog Friendly, Golf Resort Amenities

PattyRating, 5 stars9 months ago
Really felt as comfortable as being home. Loved all the labels on light switches and helpful hints throughout to make the stay easy. Probably the best stocked rental on the market- everything you need for your stay. And greatly appreciated the cold waters in the mini fridge and we used them all- again thank you!!! Great place to stay and have a little view of the Lake.
Home in Salem
4.88 out of 5 average rating, 17 reviews

Lake Keowee condo by marina&pool close to Clemson

AmandaRating, 5 stars9 months ago
Annica's place was perfect for our family. We were in town for Clemson's Family weekend. Only a 23 min drive to campus. The space was easy to get to, in a private gated community and had amenity perks for staying in the community. The 2 king size beds were super comfortable. The bathrooms, kitchen, and living areas were all decorated nicely and our group had plenty of space to spread out. We rented a pontoon boat through the community for an affordable price (perks of being in the community) and had a wonderful couple days. Would love to come back for a visit our next trio to Clemson.
Superhost
Home in Six Mile
4.87 out of 5 average rating, 38 reviews

Lake Keowee Access-Dock-Pool-Grill-Clemson 17 Min

EliRating, 5 stars1 week ago
We were there for a work trip and it was a very comfortable place to stay. Clean, quiet and relaxing. Will definitely stay again!
Guest favourite
Home in Six Mile
5 out of 5 average rating, 5 reviews

Clemson football 15 minutes away. 2 night minimum.

ChipRating, 5 stars1 month ago
Rebecca was a fantastic host. Eight of stayed at her home for Clemson Graduation weekend. When we arrived Rebecca had left us a welcome basket with multiple snacks and coffee. We had plenty of space for everyone. The home was clean, and had plenty of amenities. The kids (teenagers) loved the volleyball pool, pickleball and other lawn games. The adults enjoyed sitting on the deck in the evening with a beverage while the propane fire pit provided nice ambiance. Now that our daughter has graduated we hope to return to Clemson and would absolutely rent Rebecca's home again!
Superhost
Home in Salem
4.86 out of 5 average rating, 21 reviews

Lake Keowee Home near Clemson, boating, and hiking

Leslie NunezRating, 5 stars8 months ago
Keowee Key community is great. This place is bigger than it even seems in the pictures. Very responsive host.
Top guest favourite
Home in Salem
5 out of 5 average rating, 28 reviews

Golf view, lake access, 3 pools!

StephanieRating, 5 stars3 weeks ago
We had a wonderful stay at the Sail Loft over Memorial Day weekend! From the moment we arrived, we felt right at home. The space is so cozy, beautifully decorated, and full of thoughtful touches—it’s clear that every detail has been carefully considered. It’s just like the photos, only better in person! Nichole was the perfect host—kind, responsive, and welcoming. She guided us throughout our stay, making sure everything went smoothly and that we felt comfortable and cared for. We loved enjoying the Keowee Key amenities, especially the pool and dining at the club’s restaurants. It truly felt like a hidden gem! We’re already looking forward to coming back soon. Highly recommended for anyone looking for a peaceful retreat with all the comforts of home!
Home in Salem
4.74 out of 5 average rating, 27 reviews

* Keowee Key* Lake* Fireplace*Golf*Tennis*Gym*

Elisa SuttiRating, 5 stars2 months ago
Christina's house is amazing! We had a wonderful week in her home. It is spacious, comfortable and very clean. Equipped with all the necessary comforts and more. It also has a very large terrace. I highly recommend it!!

Weekly house rentals

Top guest favourite
Home in Six Mile
4.97 out of 5 average rating, 36 reviews

Cozy Foothills Retreat

GracynRating, 5 stars4 weeks ago
We stayed at Kathi's place for a book club trip and had a fantastic time! We loved the neighborhood and how safe we felt there. It was extremely clean and has everything you could need. The book warehouse was closed while we were there, but we hiked a few trails, went shopping, and ate at some good restaurants. I definitely wouldn't mind staying here again if we ever come back to the area.
Top guest favourite
Home in Cleveland
5 out of 5 average rating, 23 reviews

Rare 1930’s Riverfront Cottage

JadaRating, 5 stars6 days ago
We had a wonderful stay at Kelly's place! The home was easy to find, exactly as described, and ready to host us for a nice and relaxing fathers day weekend. We appreciated all of the little touches throughout the home that made us feel comfortable and welcomed. The home is spacious and the small decorating touches throughout made it feel like loved and inviting space. There were snacks on site to welcome us on our arrival, plenty of towels and toiletries available, the beds were OH SO COMFORTABLE, and we were grateful to say we didn't see not one bear during our stay. The instruction/welcome manual left by Kelly was super detailed - leaving not one question unanswered - and she was kind enough to check in with us to make sure we arrived and were settled in. We had a fun time with the kids playing in the river across the street, sitting on lovely screened in porch, and playing the various games available throughout the house. Thank you so very much!
Top guest favourite
Home in Six Mile
5 out of 5 average rating, 30 reviews

Lakefront luxury home w/panoramic view & Boat Slip

LauraRating, 5 starstoday
We had a fantastic stay at Chuck and Brenda’s beautiful Lake Keowee home with family and friends! The views and sunsets from the wrap-around deck were spectacular — it felt like we were right on the water. The house is spacious, comfortable, and full of fun amenities. We especially enjoyed the kayaks, tubes, and easy access to the community dock. Chuck and Brenda were great hosts and very easy to communicate with. Highly recommend!
Top guest favourite
Home in Easley
4.99 out of 5 average rating, 86 reviews

Taking it Easley/FirePit/Near Dwn GVL/HtTub/Silos

RyleeRating, 5 starstoday
Deana’s stay was WONDERFUL! It was spotless and had games and smores supplies that my group loved and used. It was so comfortable and had everything we needed in the kitchen. If I could give it more than five stars I could! Deana was responsive and helpful the whole time, and I couldn’t have asked for a better stay! Thank you thank you thank you!!
Guest favourite
Home in Easley
4.93 out of 5 average rating, 94 reviews

King Bed Quiet Modern Farmhouse w/ HUGE yard

MarkRating, 5 stars3 weeks ago
We have stayed in this home many times over the years as the location is perfectly situated close to our family. Josh is a very responsive host. The place is very clean and comfortable. A variety of streaming services are also available. Thank you.
Guest favourite
Home in Six Mile
4.94 out of 5 average rating, 71 reviews

3 BR House Near Clemson

AmandaRating, 5 stars4 weeks ago
Absolutely loved it. We didn’t want to leave! Sitting on the covered porch each night was the highlight of my days.
Guest favourite
Home in Central
4.95 out of 5 average rating, 19 reviews

Frankie’s Place

SandraRating, 5 stars3 weeks ago
Frankie's Place is in a beautiful country setting, still not far to great restaurants, a university town. Lovely home, very nicely furnished, very comfortable for my stay of 7 nights. Enjoyed my time on the inviting back porch. Really appreciated the high toilet and grab bars in the bathroom. l definitely recommend Frankie's Place. Frankie is a great hostess.
Superhost
Home in Brevard
5 out of 5 average rating, 4 reviews

Secluded Home | Backyard Waterfall | 3BR | events

SherryRating, 5 stars1 month ago
My girlfriends and I celebrated my birthday weekend in this amazing house. Such a beautiful location. We only left the house once as we loved the sounds of the waterfall so much. Very spacious, clean and full of the necessities we needed for a weekend away!

Private house rentals

Guest favourite
Home in Six Mile
4.96 out of 5 average rating, 73 reviews

Lake Keowee Beach Club Cabin

SamRating, 5 stars3 weeks ago
We absolutely loved our stay! What an amazing location. We spent time on the pontoon boat, kayaking, canoeing, fishing, grilling, and chilling. We will definitely be back.
Top guest favourite
Home in Seneca
5 out of 5 average rating, 31 reviews

Retreat w/ Dock & Hot Tub at Martin Creek

MikaRating, 5 stars2 weeks ago
Great weekend getaway - we had so much fun in the lake. The home is spacious and clean - plenty of room for our group of 7 adults.
Guest favourite
Home in Brevard
5 out of 5 average rating, 66 reviews

This is the One!-Just Wow-Arrowhead Point of View

KatherineRating, 5 stars5 months ago
The views were beautiful! Pictures don’t do it justice! The location was remote and peaceful, exactly what my husband and I needed! Highly recommend if you want to get away from the hustle bustle of life.
Top guest favourite
Home in Six Mile
5 out of 5 average rating, 17 reviews

DockTales - Panoramic Views & Private Dock

JessicaRating, 5 stars3 weeks ago
This was our 2nd time staying here. We love it! Plenty to do for the kids. Clean, private & super fun being just a few steps from the beautiful lake. This definitely will be a family favorite lake house to rent for many trips to come. Thank you for everything!
Top guest favourite
Home in Slater-Marietta
4.98 out of 5 average rating, 82 reviews

Robin’s Nest- Cottage in the Woods

KathyRating, 5 stars1 month ago
We loved staying at Michelle's. It was quiet and private but not too far from town or being able to go places. Great location and we loved the porch and the cabin feel of the home
Top guest favourite
Home in Six Mile
5 out of 5 average rating, 11 reviews

Lake Keowee SC Lakehouse Escape

cherylRating, 5 stars1 week ago
We had a fabulous week at your lake house! the house was perfect for our 3 generations. The game room and beds upstairs was the secret hide away for grand kids. the bedrooms were extra spacious and cozy. living space great. tops was the double deck at the lake. We were gifted with new fishing poles, floats, and corn hole game. Could not have been a more pleasant home. kitchen so organized, and clean. immediate response to any questions. loved the book choices throughout the house. We had warm greating and note for a blessed week, and blessed week it was!
Guest favourite
Home in Central
5 out of 5 average rating, 9 reviews

Games and Vacation Home Clemson !

JenniferRating, 5 stars1 month ago
The home is beautiful! One of the best stays we've had. Aline was so thoughtful throughout the house. Every room has everything a guest would need. Plenty of towels including in kitchen. The home was pristine and the outdoor space is so comfortable. We didn't want to leave!
Superhost
Home in Cleveland
4.83 out of 5 average rating, 71 reviews

Stunning 5BR Lodge | Hot Tub & Table Rock Views

MichaelRating, 5 stars1 week ago
Cabin was very cozy, area was peaceful. The patio was large and a very nice, quiet place to have coffee in the morning. The owners were very responsive and helpful. We loved the place!

Destinations to explore