
Family-friendly holiday rentals in La Mesa
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in La Mesa
Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for La Mesa family-friendly rentals
Family-friendly home rentals with a hot tub

Home at the Sanctuary

Deluxe Escape~BALCONY!Sunset & Sunrise VIEWS~

Comfy Mountain Top Casita

Da Hui Hut - La Mesa’s best view and spa

Charming Suite in Historic Home

The Outside Inn at The Tipsy Goat Ranch

NatureEscape|View•Sauna•SoakTub

Zen Airstream Experience
Family- and pet-friendly home rentals

Clean 1BR/1BA Guest House Peaceful Private Casita

The Queen House

Retro Fun, S'mores & Smiles in Bettie Blue

Lemon Drop Cozy Studio

Fletcher Hills - modern 1 BR.Easy, no step access.

Dog friendly California Cottage near SDSU

Private cozy cottage

Private Studio with a Panoramic View
Family-friendly home rentals with a pool

3 BR Urban Oasis with Pool and Spa in Great Area

Lovely Guesthouse in garden setting

Mountain Retreat Ocean View-Great for Staycation

The BEST NEST Clean, peaceful, private, affordable

Sunny SD l Pool l BBQ l Pool Loungers l Sleeps 10

Private Poolside Cabana

Bright and spacious home with views, pool & spa.

Designer Luxury Rental With Pool
Quick stats about holiday rentals that are family-friendly in La Mesa
Total rentals
260 properties
Nightly prices starting at
₹4,360 before taxes and fees
Total number of reviews
11K reviews
Pet-friendly rentals
110 properties allow pets
Rentals with a pool
80 properties have a pool
Rentals with dedicated workspaces
180 properties have a dedicated workspace
Destinations to explore
- Southern California Holiday rentals
- Los Angeles Holiday rentals
- Stanton Holiday rentals
- Las Vegas Holiday rentals
- Channel Islands of California Holiday rentals
- San Diego Holiday rentals
- Phoenix Holiday rentals
- Palm Springs Holiday rentals
- San Fernando Valley Holiday rentals
- Scottsdale Holiday rentals
- Henderson Holiday rentals
- Las Vegas Strip Holiday rentals
- Rentals with pools La Mesa
- Rentals with an EV charger La Mesa
- Rentals with a washing machine and dryer La Mesa
- Villa rentals La Mesa
- Rentals with a beach view La Mesa
- Rentals with a firepit La Mesa
- Rentals with outdoor seating La Mesa
- Pet-friendly rentals La Mesa
- House rentals La Mesa
- Private suite rentals La Mesa
- Fitness-friendly rentals La Mesa
- Rentals with breakfast La Mesa
- Rentals with a hot tub La Mesa
- Guest house rentals La Mesa
- Rentals with a patio La Mesa
- Flat rentals La Mesa
- Rentals with beach access La Mesa
- Smoking-friendly rentals La Mesa
- Rentals with a fireplace La Mesa
- Family-friendly rentals San Diego County
- Family-friendly rentals California
- Family-friendly rentals United States
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- Balboa Park
- Windansea Beach
- Santa Monica Beach
- Playas Los Buenos
- Playa Popotla
- Morgan Run Club & Resort
- University of California San Diego
- Silver Strand State Beach
- Liberty Station
- Cardiff State Beach
- Torrey Pines Gliderport
- Citizens Trail
- Mission Trails Regional Park
- St Malo Beach
- South Oceanside Beach
- Gladiator Beach
- Strand Beach
- Buccaneer Beach
- Oceanside Harbor Beach
- Carlsbad State Beach
- Emerald Isle Golf Course
- Grandview Surf Beach
- Turnarounds Beach
- LEGOLAND California