Guest house holiday rentals in East County, San Diego

Find and book unique guest house rentals on Airbnb

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Popular amenities for guest house rentals in East County, San Diego

Family-friendly guest house rentals

Guest favourite
Guest house in La Mesa
4.93 out of 5 average rating, 240 reviews

Fig Tree Bungalow

TomasRating, 5 stars3 days ago
Comfortable place, easy check-in and responsive, friendly host.
Top guest favourite
Guest house in La Mesa
4.99 out of 5 average rating, 279 reviews

Spacious, private Mt. Helix country style studio

RhondaRating, 5 stars1 month ago
Absolutely worth it. Beautiful place. Cozy with gorgeous gardens. Also a nice welcome touch of bowl of fruits, chocolates and plenty to drink. Loved it.
Top guest favourite
Guest house in San Diego
4.97 out of 5 average rating, 187 reviews

New Guest House - North Park

SarahRating, 5 stars2 weeks ago
This property was perfect. So beautiful, cozy, clean and well-equipped. It felt private but was a short walk to great restaurants, coffee shops and cute boutiques. We were traveling with an infant and Lynae went above and beyond in providing little extras that helped to make things easy for us. Would gladly stay here again.
Top guest favourite
Guest house in Dulzura
4.97 out of 5 average rating, 624 reviews

Vineyard & Winery Guest House

SusanRating, 5 stars1 month ago
We totally enjoyed our stay at Grant & Sarah’s place. It was very comfortable, clean and welcoming. The wine was delicious, but their company was even more enjoyable. Would highly recommend a stop there!
Guest favourite
Guest house in San Diego
4.93 out of 5 average rating, 195 reviews

Cosy quiet Guesthouse near SDSU

SandyRating, 5 stars4 weeks ago
Desiree is such a sweet host! My husband, five month old, and I stayed in her Airbnb and we very much enjoyed our time. The place was well kept and clean. She had the guest house stocked with all the essentials which made it so nice and convenient. Anytime we had a question or request, she was quick to respond and resolve. The location is close to many great coffee shops, restaurants, and things to do. Glad we found this place and would definitely book it again in the future!!
Guest favourite
Guest house in La Mesa
4.93 out of 5 average rating, 164 reviews

Granny Flat with Bedroom/Bathroom/Kitchen

AlexisRating, 5 stars1 week ago
Staying at Janet’s was truly a 5 star experience. Janet is a lovely host and the granny flat was cozy, cute, and very clean. The property is located in a beautiful, quiet residential neighborhood not too far from all the tourist attractions of San Diego. I would absolutely not hesitate to stay here again in the future.
Guest favourite
Guest house in San Diego
4.97 out of 5 average rating, 582 reviews

Central & Serene Secret Garden Guesthouse

JenniferRating, 5 stars3 weeks ago
We loved Susie’s garden guesthouse! Very walkable to a lot of lovely restaurants and close to SDSU!
Superhost
Guest house in Spring Valley
4.88 out of 5 average rating, 207 reviews

San Diego family bungalow!

SarahRating, 5 stars4 days ago
This is an ideal, affordable, family friendly stay. They have a stroller and high chair in the closet, fresh garden we were invited to eat from, lawn games and endless fun in the awesome pool. They had a fire prepped and towels supplied. Oh! And tons of beach stuff to borrow! They were excellent hosts and we had an amazing visit.

Guest house rentals with a patio

Top guest favourite
Guest house in Escondido
4.99 out of 5 average rating, 138 reviews

Garden Casita

EbehlinRating, 5 stars1 day ago
We enjoyed our stay at la casita, it was peaceful and felt like home. La casita is stunning and has a beautiful garden. We love la casita and for sure will be back whenever we visit again. Thank you pete for allowing us to stay for the weekend ✨
Top guest favourite
Guest house in San Diego
4.99 out of 5 average rating, 209 reviews

Adorable cottage in Talmadge

NysaRating, 5 stars2 weeks ago
The place was exactly as described. It was clean, peaceful and private. Their landscape was beautiful with all of the different flowers. Carlos was great with communication and a pleasure to interact with. He made things as simple and straightforward as possible. We would definitely stay at his lovely place again.
Top guest favourite
Guest house in Poway
4.98 out of 5 average rating, 108 reviews

Gorgeous Guesthouse Poway w/Private Yard

ToniRating, 5 stars2 weeks ago
We had a great stay. The place was very clean, private, and beautifully decorated. It felt comfortable and welcoming. Would happily stay here again.
Top guest favourite
Guest house in San Diego
4.98 out of 5 average rating, 210 reviews

La Jolla Oasis: Ocean, City and Fire Works Views

HannahRating, 5 stars2 weeks ago
Atoosa was a great host, extremely responsive and helpful before and during our stay. Her apartment is gorgeous and had everything we needed. The views and balcony were great for evening drinks. 100% recommend for anyone looking to enjoy La Jolla
Top guest favourite
Guest house in La Mesa
4.97 out of 5 average rating, 205 reviews

Da Hui Hut - La Mesa’s best view and spa

JerryRating, 5 stars2 weeks ago
We've visited San Diego for years and enjoy this area of the city to visit family, get great mid-eastern food and visit Mount Helix. Mr. Helix has spectacular views from the Mexican Border to North County San Diego and this Da Hui Hut gave a front row seat since its located on it! The Hawaiian atmosphere made my wife feel like see was back home in Kona. This place offered exceptional value and we can't wait to visit again.
Top guest favourite
Guest house in Julian
4.95 out of 5 average rating, 259 reviews

Cozy Country Cottage with increíble veiws

IsaacRating, 5 stars4 weeks ago
A cozy home with a beautiful view. Cherri is an extremely nice host and we hope to visit again :)
Superhost
Guest house in San Diego
4.86 out of 5 average rating, 266 reviews

Heart of SD | Zoo Nearby | Private Patio | Central

TatianaRating, 5 stars1 week ago
Was quiet but still close enough to all the activities and restaurants. Perfect for a couples getaway.
Top guest favourite
Guest house in Ramona
4.96 out of 5 average rating, 125 reviews

Adorable Hawaiian themed Guest House

DonovanRating, 5 stars6 days ago
Everything was cool from the house to the pool to Louis. The dog the zip line in all felt really homey .

Guest house rentals with a washing machine and dryer

Guest favourite
Guest house in San Diego
4.98 out of 5 average rating, 136 reviews

Private Guest House for 2 with Kitchen + Laundry

CarsonRating, 5 stars1 week ago
This was a very comfy apartment for 1, and can easily fit 2. I loved that there was an in-unit washer and dryer, along with many necessities in both the kitchen and the bathroom. There’s also a nice yard out back which I wasn’t able to use only because I was busy, but would make for a very tranquil spot to have a meal! The yard itself is teeming with healthy plants too and is overall a really nice vibe. Thanks again for hosting!
Top guest favourite
Guest house in La Mesa
4.99 out of 5 average rating, 189 reviews

Stunning Guest House 15 min. from Zoo, Downtown

HjRating, 5 stars6 days ago
Amazing cottage with a full kitchen and bathroom as well as a living room, decorated with exceptional sense of aesthetics. Its double doors opens to a great porch where you can enjoy wine and cheese at California evening, but you can also enjoy the clear sky during the day through the screen doors. It is so close to the downtown La Mesa with many great restaurants. Lynn was a great host and her freshly baked bread was so tasty as well. One of the best AirBNB I have experienced; highly recommended.
Top guest favourite
Guest house in San Diego
4.99 out of 5 average rating, 148 reviews

The Happy Family * 2 playhouses near SDSU!

JasmineRating, 5 stars4 days ago
The guest house is AMAZING!! So super cute and family friendly. Loved and appreciated how easy the kids beds were to set up. The play houses were of course such a big hit with my kids (4 & 7yo), they literally didnt want to come inside! My husband and I loved lounging in the blue patio chairs while the kids played. So peaceful and relaxing! The beach towels and toys were awesome and we also appreciated little things like a step stool and some honest juice boxes in the fridge when we checked in! Couldn't recommend this place more and we look forward to another summer in San Diego to stay here again :)
Guest favourite
Guest house in San Diego
4.93 out of 5 average rating, 364 reviews

*BEAUTIFUL* Sunny Home in Golden Hill

TiffanieRating, 5 stars2 weeks ago
Great stay - the property was just as listed and had everything you would need for your stay. Would definitely recommend.
Superhost
Guest house in Lemon Grove
4.9 out of 5 average rating, 231 reviews

"Glam Farmhouse dream cottage"🏠🌠

CapsRating, 5 stars2 weeks ago
This was my second time staying here, and it was just as great as the first. The place is spacious, comfortable, and has everything I needed for a smooth and relaxing stay. It’s well-equipped and very convenient. Benito made everything simple and stress-free, as always—his hospitality is much appreciated. I’m already looking forward to coming back!
Top guest favourite
Guest house in Rancho Santa Fe
4.99 out of 5 average rating, 167 reviews

Rancho Relaxo / Spacious Detached Guest House

ChenetteRating, 5 stars1 week ago
Had the most relaxing solo vacay at Britt and Susie’s pool house. The house was exactly as described. I felt safe and comfortable. I was greeted by Britt when I arrived and he explained how to use all the house amenities. I enjoyed the pool and hot tub each day, which were very clean and well-landscaped. This place is a dream for a couple or solo traveler like me!
Guest favourite
Guest house in San Diego
4.93 out of 5 average rating, 151 reviews

Clean Cozy Private Guesthouse - Central San Diego

RobertRating, 5 stars1 day ago
This place is as advertised. We really appreciated the dedicated parking and private yard for our pup. We had no issues with noise and felt like we had complete privacy. It was very easy to get around as we traveled to PB, Coronado and ocean beach while we stayed. Will definitely book this stay again.
Guest favourite
Guest house in San Diego
4.93 out of 5 average rating, 590 reviews

Quaint Craftsman#2- Walkable, Parking, EV Charging

TiffanyRating, 5 stars2 weeks ago
This airbnb was clean, comfy, and had a lot of great amenities available. I liked that it was in walking distance of a lot of shops and restaurants. Christina was a great host, friendly and responsive. She provided good suggestions for things to do in the area. I would recommend this listing anyone looking to stay in San Diego.

Destinations to explore