
Holiday rentals in Panhandle Key
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Panhandle Key
Guests agree: these stays are highly rated for location, cleanliness and more.
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Popular amenities for Panhandle Key holiday rentals
Other great holiday rentals in Panhandle Key
Guest favourite

Houseboat in Marathon
5 out of 5 average rating, 19 reviewsAdventurers escape breathtaking off-grid houseboat
YulieskaRating, 5 stars2 weeks ago
A great experience, beautiful place. Joe is fantastic. Always attentive and willing to help.
Guest favourite

Cottage in Islamorada
4.96 out of 5 average rating, 85 reviewsIslamorada bungalow 2 bed & pool
AmandaRating, 5 stars4 days ago
The hosts were very responsive and accommodating to our needs. The pool was great and the place was pristine!
Top guest favourite

Cottage in Islamorada
4.95 out of 5 average rating, 41 reviewsWaterfront Cottage Walk to World Famous Lorelei
JustinRating, 5 stars3 weeks ago
What an amazing place! My wife and I have stayed in Airbnb properties all over the world, and this was one of our favorites. Exactly as described. Very clean, safe, and comfortable. The location and layout of the property is absolutely perfect and private. This was our first time to Islamorada and this place made it an even better experience. We had a manatee sighting and the deck over the water was my favorite part. Perfect place to have a drink and watch the sunset. If you are planning a trip to the keys, do yourself a favor and stay here.
Guest favourite

Apartment in Tavernier
4.94 out of 5 average rating, 98 reviewsYour Happy Place - Oceanfront
JeffreyRating, 5 stars1 month ago
We thoroughly enjoyed our stay, the property was as described and the pool and bar/restaurant were great! The room in building 4 and floor 4 was perfect for views off the small balcony! Would 100% stay here again!!
Guest favourite

Home in Marathon
4.96 out of 5 average rating, 26 reviewsMillion Dollar View
JohnRating, 5 stars1 month ago
This home was everything we expected and more. Stunning location with absolute privacy. The extra long dock was amazing, the pool was fantastic, and the grounds were meticulous. It’s literally your own private resort. Roman, the host, was very quick with communication. He and his wife actually met us when we checked in to see if we had any questions and provided us with an arrival gift. If you have looked at the listing and are thinking of renting it, do it. You will not be disappointed at all. Excellent value all around.
Guest favourite

Bungalow in Islamorada
4.96 out of 5 average rating, 54 reviewsCastaway Island - Pool, Spa, Tiki Bar, Kyaks,Sup’s
BenRating, 5 stars3 weeks ago
Regina and Captain Rob were great hosts! They gave us local recommendations and communicated well! We had such a great time using the tiki bar and the pool. It was our first trip with our baby and the place even had a crib for us to use. Would definitely return!
Superhost

Home in Key Largo
5 out of 5 average rating, 4 reviewsNewely Renovated 3/2-private pool/dock/cabana club
OliviaRating, 5 stars1 week ago
Absolutely amazing place to stay! Dennis is amazing and had several great recommendations for us to eat and do! The dock out back was beautiful and we were even able to see manatees! The pool was a GREAT addition and my family wouldn’t have wanted to explore the Keys any other way! The neighbors are also friendly and great to talk to! Overall beautiful place! My family and I would stay again!
Superhost

Flat in Marathon
4.72 out of 5 average rating, 248 reviewsKnight's Key Suites Deluxe Double Room w/ Kitchen
SeanRating, 5 stars4 days ago
Very pleasant stay at this suite. Great view of the bridge from the front. The immediate area is quite quiet, even with the Sunset Grille just a few hundred yards away. Would definitely stay there again in the future!
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- Everglades National Park
- Sombrero Beach
- John Pennekamp Coral Reef State Park
- Zoo Miami
- Bahia Honda State Park
- Coral Castle
- Biscayne National Park
- Cannon Beach
- Conch Key
- Calusa Beach & Loggerhead Beach
- Everglades Alligator Farm
- Theater of the Sea
- Cocoa Plum Beach
- EAA Air Museum
- Long Beach
- Sea Oats Beach
- Horseshoe Beach
- Far Beach
- Monkey Jungle
- Windley Key Fossil Reef Geological State Park
- Highland Beach
- Long Key State Park
- Keys' Meads