
Holiday rentals in Panhandle Key
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Top-rated holiday rentals in Panhandle Key
Guests agree: these stays are highly rated for location, cleanliness and more.
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Holiday rentals for every style
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Popular amenities for Panhandle Key holiday rentals
Other great holiday rentals in Panhandle Key
Guest favourite

Home in Marathon
4.94 out of 5 average rating, 31 reviewsPrivate Home,Hot Tub,BBQ.Boat & RV Parking FL Keys
Guest favourite

Villa in Key Largo
5 out of 5 average rating, 13 reviewsFull Ocean View Luxury Villa | Gym & Beach Club
Top guest favourite

Boat in Marathon
5 out of 5 average rating, 58 reviewsDan’s 2024 catamaran cruiser vessel can’t be moved
Top guest favourite

Home in Key Colony Beach
5 out of 5 average rating, 7 reviewsKeys to Ohana. Ocean views. Private Pool, Hot Tub
Top guest favourite

Apartment in Duck Key
5 out of 5 average rating, 38 reviewsBlue Haven
Guest favourite

Bungalow in Islamorada
4.97 out of 5 average rating, 59 reviewsCastaway Island - Pool, Spa, Tiki Bar, Kyaks,Sup’s
Top guest favourite

Flat in Tavernier
5 out of 5 average rating, 61 reviewsWhen Paradise is Key: Tropical Oceanfront Condo
Superhost

Home in Key Largo
4.91 out of 5 average rating, 58 reviewsTreetops
Destinations to explore
- Seminole Holiday rentals
- Central Florida Holiday rentals
- Miami Holiday rentals
- Orlando Holiday rentals
- Saint Johns River Holiday rentals
- Gold Coast Holiday rentals
- Miami Beach Holiday rentals
- Havana Holiday rentals
- Fort Lauderdale Holiday rentals
- Tampa Holiday rentals
- Kissimmee Holiday rentals
- Four Corners Holiday rentals
- Everglades National Park
- Sombrero Beach
- John Pennekamp Coral Reef State Park
- Zoo Miami
- Biscayne National Park
- Coral Castle
- Cannon Beach
- Calusa Beach & Loggerhead Beach
- Cocoa Plum Beach
- Theater of the Sea
- Conch Key
- Far Beach
- Everglades Alligator Farm
- Monkey Jungle
- Horseshoe Beach
- Sea Oats Beach
- EAA Air Museum
- Long Key State Park
- Windley Key Fossil Reef Geological State Park
- Bahia Honda State Park
- Keys' Meads
- Sandspur Beach
- Long Beach
- Schnebly Redland's Winery & Brewery