Guest house holiday rentals in Lexington County
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Lexington County
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
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Popular amenities for guest house rentals in Lexington County
Family-friendly guest house rentals
Guest house in Columbia
4.89 out of 5 average rating, 87 reviewsCozy Camper in St. Andrews, Irmo, Harbison Blvd.
21–28 Nov
Guest house in Columbia
4.08 out of 5 average rating, 39 reviewsCoziest Studio Cabin near USC, 5 pts & Hospitals
26 Jul – 2 Aug
Guest house in Columbia
5.0 out of 5 average rating, 371 reviewsCozy studio apartment, convenient location
1–8 Sep
Guest house in West Columbia
4.94 out of 5 average rating, 600 reviewsCarriage House: Studio Bed & Bath - Pool & Hot Tub
8–15 Aug
Guest house in Lexington
4.94 out of 5 average rating, 247 reviewsCome Pause and Relax!
5–12 Jul
Guest house rentals with a patio
Guest house in West Columbia
5.0 out of 5 average rating, 10 reviewsAviation A-Frame Airbnb
28 May – 4 Jun
Guest house in Columbia
5.0 out of 5 average rating, 66 reviewsRestful Refuge
27 Jul – 3 Aug
Guest house in Columbia
4.95 out of 5 average rating, 19 reviewsThe Wren | 1BR 2BA Guesthouse
11–18 Jul
Guest house in Lexington County
4.96 out of 5 average rating, 24 reviewsMom's Place
11–18 Nov
Guest house in Columbia
4.95 out of 5 average rating, 82 reviewsQuaint Haven: Your Cozy Retreat
19–26 Oct
Guest house in Batesburg-Leesville
5.0 out of 5 average rating, 6 reviewsBeautiful Lake Front 1 bedroom Guest House
19–26 May
Guest house in Lexington
5.0 out of 5 average rating, 50 reviewsA Pondside Oasis close to Lake Murray and Columbia
17–24 Apr
Guest house in Chapin
4.95 out of 5 average rating, 22 reviewsNEW Lakefront guesthouse with private dock.
16–23 Apr
Guest house rentals with a washing machine and dryer
Guest house in Lexington
5.0 out of 5 average rating, 5 reviewsGarage Apartment
25 Nov – 2 Dec
Guest house in Columbia
4.98 out of 5 average rating, 87 reviewsBrand New Studio Guest House with Full Kitchen.
30 Jan – 6 Feb
Guest house in Gilbert
4.88 out of 5 average rating, 95 reviewsShull Island Retreat
5–12 Jan
Guest house in West Columbia
4.96 out of 5 average rating, 45 reviewsSpringdale Getaway
29 Apr – 6 May
Guest house in Columbia
4.89 out of 5 average rating, 66 reviewsFaber's Rest LLC
1–8 Jun
Guest house in Columbia
4.94 out of 5 average rating, 32 reviewsCasa Abelia - Downtown Columbia
5–12 Sep
Guest house in Columbia
5.0 out of 5 average rating, 13 reviewsTrendy 1 Bed/1 Bath in quiet upscale neighborhood
18–25 Jul
Guest house in Columbia
4.97 out of 5 average rating, 37 reviewsGraymont Place | Cottage near USC, Downtown, Vista
26 Nov – 3 Dec
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