
Villa holiday rentals in James Island
Find and book unique villas on Airbnb
Top-rated villa rentals in James Island
Guests agree: these villas are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for villa rentals in James Island
Private villa rentals

Spacious 1BR | Balcony | Private W/D |

Lovely new rental in popular Turtle Cove

Coastal 3BR in Old Village with patio & yard

Lovely 1BR 3rd-Floor | Balcony | Pool

Upscale, Private,Breathtaking Views

Coastal Villa with all the Comforts of Home!

New! Oceanfront with amazing views in popular area

Port O' Call F102 - Oceanfront Oasis w/ Walkout!
Luxury villa rentals

Coastal Manor

Links Clubhouse 2 by Wild Dunes, with Amenities

711 Spinnaker centrally located to everything!

Ocean 180 | Easily Best Oceanfront View | All New

Beachfront IOP Villa with Outdoor Pool. Remodeled!

Comfy Cool-Pool-River Views-Beautifully Updated

Amenity Cards+Views+Dogs OK

Luxury Seabrook Isl Beach Condo
Villa rentals with a pool

Fairway Dunes 12 - Beach & Golf Lovers Dream!

Dog friendly villa on 8th hole of golf course

Beach Club Villa 32 - Elite Oceanfront! Pool!

Seascape 317 - View! Beach! Pool!

Linkside Court 21 - Community Tennis/Pickleball!

Fairway Dunes 11 - Immaculate Remodel! Pickleball!

Tidewater H301 - Top Floor End Unit! Pool!

Tree top living on Seabrook Island!
Destinations to explore
- Saint Johns River Holiday rentals
- Western North Carolina Holiday rentals
- Atlanta Holiday rentals
- Myrtle Beach Holiday rentals
- Charleston Holiday rentals
- Gatlinburg Holiday rentals
- Charlotte Holiday rentals
- Hilton Head Island Holiday rentals
- Savannah Holiday rentals
- Jacksonville Holiday rentals
- Pigeon Forge Holiday rentals
- Cape Fear River Holiday rentals
- Rentals with outdoor seating James Island
- Family-friendly rentals James Island
- Rentals with a patio James Island
- Rentals with pools James Island
- Rentals with a hot tub James Island
- Bed and breakfasts James Island
- Rentals with beach access James Island
- Beachfront rentals James Island
- Private suite rentals James Island
- Boutique hotel rentals James Island
- Pet-friendly rentals James Island
- Rentals with a washing machine and dryer James Island
- Townhouse rentals James Island
- Rentals with a kayak James Island
- Rentals with lake access James Island
- Fitness-friendly rentals James Island
- Rentals with an EV charger James Island
- Rentals with breakfast James Island
- Waterfront rentals James Island
- House rentals James Island
- Rentals with a firepit James Island
- Guest house rentals James Island
- Rentals with a fireplace James Island
- Flat rentals James Island
- Apartment rentals James Island
- Villa rentals Charleston County
- Villa rentals South Carolina
- Villa rentals United States
- Park Circle
- Hunting Island State Park Beach
- Sullivan's Island Beach
- Bulls Island
- Middleton Place
- James Island County Park
- Waterfront Park
- The Golf Club at Wescott Plantation
- Shem Creek Park
- Harbor Island Beach
- Hampton Park
- Angel Oak Tree
- The Charleston Museum
- Secession Golf Club
- Isle of Palms Beach
- Bull Point Beach
- Morris Island Lighthouse
- Seabrook Island Beach
- Hunting Island Beach
- Charleston Aqua Park
- Gibbes Museum of Art
- Edingsville Beach
- White Point Garden
- Seabrook Beach
- Things to do James Island
- Tours James Island
- Food and drink James Island
- Sports activities James Island
- Sightseeing James Island
- Nature and outdoors James Island
- Things to do Charleston County
- Tours Charleston County
- Food and drink Charleston County
- Sports activities Charleston County
- Art and culture Charleston County
- Sightseeing Charleston County
- Nature and outdoors Charleston County
- Things to do South Carolina
- Sports activities South Carolina
- Art and culture South Carolina
- Wellness South Carolina
- Tours South Carolina
- Entertainment South Carolina
- Nature and outdoors South Carolina
- Sightseeing South Carolina
- Food and drink South Carolina
- Things to do United States
- Entertainment United States
- Wellness United States
- Sports activities United States
- Art and culture United States
- Tours United States
- Food and drink United States
- Sightseeing United States
- Nature and outdoors United States














