
Pet-friendly holiday rentals in Cape Girardeau
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Cape Girardeau
Guests agree: these pet-friendly homes are highly rated for location, cleanliness and more.

5 Star Worthy? Try 500, Star Gazer | OffGrid GLAMP
Escape completely in an off-grid glamping cottage with fire pit, deck, woods + stars! ★ "It’s truly a wilderness dream… the cabin is immaculate & so cozy." ☞ 600ft² / 56m² elevated cottage (7ft up) ☞ Zero light pollution ☞ Solar/propane fueled ☞ 1000W battery generator ☞ Drinking water ☞ Dry toilet- indoor, odorless- ask for details ☞ Kitchen galley stocked ☞ Zero gravity indoor/outdoor chairs ☞ Hammocks ☞ Floor fans available- a/c limited- ask 9 mins → DT Perryville (cafes, dining, shopping)

Downtown Loft Amazing Bath Tub & Shower
Downtown Perryville, MO **DISCLAIMER** you will hear restaurant chatter & music if you do not have a tv/or radio playing between the hours of 10:30am & 1:30am. If you go to bed early I recommend headphones, ear plugs or play nature sounds on Alexa. This is a pet friendly loft apartment so I would not recommend if you are allergic to dogs or cats. This apartment is located above one of the most popular destination restaurant's around "Mary Jane Burgers & Brew" on the Downtown Historic Square.

Herman's Corner Cottage.
Tucked in historic Cape Girardeau, this charming cottage offers comfort and convenience. Enjoy the cozy back deck with a privacy fence—perfect for relaxing or grilling. With ample off-street parking, your stay is stress-free. The home is equipped with essentials for a smooth, hassle-free visit. Book the entire house for added privacy, providing a peaceful retreat for you and your guests. Experience the perfect blend of comfort, affordability, and convenience during your Cape Girardeau getaway.

Brand new 2 bedroom unit right in downtown Cape.
This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Riverwalk Loft 1
If you are looking for something right in the middle of the excitement, book now! This is your place. Our lofts are right in the heart of Downtown. In walking distance to breweries, casinos, and shopping galore.Our building is directly in front of the Mississippi River entrance. Walk around the corner either to get an ice cream for a late night snack. Beds are super comfortable but downtown isn’t the quiet part of town. The train runs periodically. You will have the typical night life noise.

House Of Clubs- 2 Bed 1.5 Bath
The PERFECT hideway. The House of Clubs offers a quiet setting with a creek that wraps around the enitre property. Two bedrooms, each include a queen size bed. One Full bathroom. Full Laundry room that also offers a private cammode. The stylish living room offers a unique style that higlights Cape Girardeaus rich history. Enjoy your morning coffee in the four seasons room with breathtaking views of this hidden gem . Less than 5 minutes to downtown. Only 2 minutes to Cape Country Club.

Tiny House of Paul - Center For Lost Arts
Perfect if you're working or spending time exploring Southern Illinois. Great discount for longer stays. Tiny House of Paul house has a cozy & spacious feel. A large west-facing window looks out onto the forest. Windows in the loft open to tree tops & stars. Private inside. Centrally located on the property of Center For Lost Arts near Cobden, Illinois. Wander the trails at the end of a work day, or relax on the deck after hiking or exploring. Enjoy your time in Southernmost Illinois.

Downtown Penthouse w/ Amazing River View!
AMAZING RIVERVIEW Plus Close to Downtown Cape? Our Airbnb is the best place to be! Relax in our Roof Deck after going around downtown and ENJOY THE VIEW. Located in a safe and quiet neighborhood plus it is WALKING DISTANCE from everything! It features a roof deck with (by far) the best view in Cape, enough space for six to sleep (two queen beds and two couches), one off street parking spot and a building with secure entry. Plus we just live across the street if you need anything.

Under the Stars - Farmhouse
Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

Couples Retreat in the Trees + Hot tub
The TreeLoft is a custom built luxury treehouse for two nestled in the eastern part of the Ozark Mountains. Enjoy the gas fireplace for a cozy evening ambiance, a private hot tub under the stars, roasting s'mores over an evening fire or an early morning soak in the free standing tub. All of this is located within 20-45 minute scenic drive of hiking trails, wineries, and restaurants . It is our hope that upon your stay you will be reconnected to nature and to the one you came with.

Visit the "Gone Girl" neighborhood
Living rm/bedrm, full kitchen, ADA bath, and walk in closet. Fully equipped with dishes,linens, refig, micro,stove, keurig, dishwasher and welcome home snacks. Double Murphy bed, queen hide a bed couch convert the living room to bedroom. Space is good for up to 3 adults, 2 adults and 2 children or a single guest. We accept well mannered dogs up to 50 pounds. We do not accept CATS. Like cats but they cause additional clean up. See pets section for dog guest guidelines.

Panthers Inn Treehouse
Come nestle amongst the leaves at Panthers Inn Treehouse. This secluded, well equipped, elevated cabin has the perfect combination of natural beauty and artful luxury. Isolated yet conveniently located 2 minutes from Blue Sky and Feather Hill wineries, within 5 minutes of Panthers Den hiking trail and the Shawnee Hills canopy tour and only 10 min from I-57 exit 40. Panthers Inn is the perfect starting and ending point to your Shawnee Hills Wine Country vacation!
Popular amenities for Cape Girardeau pet-friendly home rentals
Pet-friendly house rentals

Happy home for traveling professionals

Priv 2br1ba Floor:Nurse & SEMO campus Friendly

Cedar Lake Retreat A

Owls Nest

The SHAWNEE PEACH

Located near downtown and casino

Shawnee Forest Vacation Lodge

Cottage Near Casino
Pet-friendly home rentals with a pool

Glamping W/Hotub, pool, & lake

Rustic Bass Cabin KK3

Coyote Cabin F09

Greenway Getaway

Camp in quiet w/ Spa Lake Pool

Racoon Cabin D09

Wooded, Private Lake, Pool & Spa

The Just Breathe Suite
Private, pet-friendly home rentals

°SeVenFold Stay~Woods, Wine and Wellness

Shady Lakes Escape

Twisted Sister's Retreat

Magical Victorian near hiking / wine trail

[*Charming Cozy Suite*]

Sweet Little House w/Fenced Yard

Historic Riverside Getaway

Lake front getaway for 2!
When is the best time to visit Cape Girardeau?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ₹10,541 | ₹10,014 | ₹9,751 | ₹9,751 | ₹10,278 | ₹10,278 | ₹10,541 | ₹9,224 | ₹9,224 | ₹10,541 | ₹10,541 | ₹9,663 |
| Avg. temp | 1°C | 4°C | 9°C | 14°C | 20°C | 25°C | 26°C | 25°C | 21°C | 15°C | 8°C | 3°C |
Quick stats about holiday rentals that are pet-friendly in Cape Girardeau

Total holiday rentals
Explore 50 holiday rentals in Cape Girardeau

Nightly prices starting at
Cape Girardeau holiday rentals start at ₹3,514 per night before taxes and fees

Verified guest reviews
Over 3,740 verified reviews to help you choose

Family-friendly holiday rentals
20 properties offer extra space & child-friendly amenities

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wifi availability
50 of Cape Girardeau holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Cape Girardeau rentals

4.8 Average rating
Cape Girardeau stays are highly rated by guests – averaging 4.8 out of 5!
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