
Apartment holiday rentals in Sant'Isidoro
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Sant'Isidoro
Guests agree: these apartments are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Sant'Isidoro apartment rentals
Weekly apartment rentals

Oasi Cenata, Pomegranate apartment
This place is beyond special. Set in the carriage house of a splendid villa estate. The location was perfect for us, between lovely Nardo and the gorgeous waterfront of Santa Caterina. Anna and Carlo are gracious and generous hosts, it was our great pleasure to get to know them a little bit during our stay. They are passionate gardeners and conservationists and this passion was evident in all that they did. We were greeted with fruit and herbs from the garden and delicious local wine. The casa (there are two, side by side) was spotless and beautifully decorated, the pool just perfect. We hope to return one day. Thank you Carlo and Anna for sharing your beautiful place with us.

Apartment in the Historic Center
We could not imagine the experience to be any better. The accomodation is excellent, clean and perfectly located. Antonio was very accommodating and responded quickly to our questions. Did I mention the bottle of wine he left for us 𤣠if your heading to Lecce you will not be disappointed staying here..đ

Apartament with kitchen
Perfect week in Porto Cesareo between sea and complete relaxation. Clean and essential house a stone's throw from the center, the sea and all kinds of shops. We only took the car to go to the nearby beaches, such as Punta Prosciutto and Torre Chianca. Too bad the vacation is over, I would have gladly stayed a little longer.

Sea and Nature House 3
Very clean accommodation, very quiet, but it should be noted that we had no neighbors above. The terrace overlooking the garden is lovely.

Living Castro Apartments - Appartamento Vista Mare
The apartment is very nice, larger than shown in the photos and sparkling clean. On the balcony it is fantastically beautiful, the view, the tranquility! The old town and harbor are within walking distance by stairs. The supermarket in Castro A&O also offers everything you need, even fresh sausage and meat products. In the harbor are beautiful bars where you can enjoy the evening sun. Nunzio and his wife are very friendly and helpful. Thanks for everything.

Lecce Amphiteatre luxury Suite
Had a wonderful stay and the hosts could not have been more welcoming. Beautiful apartment that is very centrally located. Thank you for everything!

Suite with terrace in charming Masseria for 2
We loved the property. Sophia was a perfect host. When we forgot our home keys, she made sure we collect them without a problem. If we can we want to come back with our friends to enjoy this beautiful farm house during summer. It would be perfect for 3-4 families as a base.

Studio apartment in the center a stone's throw from the Marine
A very comfortable place to stay in a great area
Private apartment rentals

Luci D'Oriente : Mediterranean sunshine sea view.
Lucci dâOriente exceeded our expectations. The apartment is spacious, cheerfully decorated and equipped with absolutely everything - nothing is missing. From each window you can see the sea, as if you were inside it. The terrace with direct access to the sea is a real privilege. Going up from there to the apartment takes some effort, but it's totally worth it. It is ideal for a family with children, very comfortable and functional. Santa Cesarea Terme is quiet, with some options to eat light and enjoy an ice cream. Parking lot next door is free if there is a place, and very accessible if paid. Rita and Stefano were exceptional hosts: attentive, friendly and always available. They made us feel right at home. We would definitely go back!

The house of the Prickly Pear with a romantic terrace
Perfect stay right near the beach that felt like home! This property has super comfortable beds, nice linens and many little things that made for a very relaxing stay. We thought weâd visit a number of the villages in the area, but found ourselves just wanting to relax at the house and on the local beaches instead. If we come back to the area, we are 100% staying here again. Also, although there are good restaurants in town, cooking was easy bc thereâs a BBQ on the patio, lots of spices and pots/pans to cook with and plenty of plates/cups/glasses/etc. Itâs a well stocked kitchen - much more so than many other places Iâve stayed. If youâre thinking about this place, stop looking at other options and book it. You wonât regret your decision. Thanks so much for a wonderful stay!!

Saponea 13 Design Flat
Francescaâs apartment is clean, spacious, had everything we needed and was in a perfect location. If you are staying in Lecce this apartment is in the best location for enjoying the restaurants and architecture. Lecce was also a perfect location to visit southern Puglia beaches. Francesca was a lovely host, very responsive and gave a lot of good recommendations. I would highly recommend this apartment.

Buccarelli Palace
A wonderful stay. The apartment was very clean. The main bedroom is on the street so is quite loud at night and in the early morning, but the location is amazing for exploring. The staircase is tight and steep, but no problem for us. A lovely, well furnished, shaded deck upstairs. We were getting multiple messages a day from the lady who checked us in. About putting out garbage etc. Maybe all this info in one message would be better than constant messaging. But other than that we really had a wonderful stay.

Hector apartment 4
Really pleasant stay in Sonia's studio apartment. Quiet place, away from the chaos of the center. Free parking outside the property. New everything, very nice and clean. Sonia met all our requests (bed linen/bath towels and beach towels all new!). A small issue was resolved immediately. Sonia is always available and responds immediately to both calls and messages. Excellent base for touring Salento and discovering the best beaches. Thank you Sonia

Beautiful Private suite
We had a lovely stay in Lecce, thanks to Marion. She was extremely kind and welcoming, and went above and beyond by providing thoughtful, detailed recommendations that truly enhanced our experience. She checked in with us regularly to make sure we had everything we needed, which we appreciated so much. The apartment itself was beautiful, comfortable, and full of character, and such a peaceful place to return to after exploring the city. Unfortunately, we had to leave earlier than planned due to a long drive and poorly timed flights on our part, but we truly wish we could have stayed longer. This was a 10/10 experience, and we hope to return one day. Highly recommend!!

Casa Cardami 22, Apartment 1A
The view is fantastic. Navigating the drop off and pick up of bags seemed like it might be a bit tricky as it's located in a historic no vehicle area but it was actually pretty simple. There are lovely terraces with great views but because it was just two of us sitting on the balcony for morning coffee and evening sunsets was perfect.

La Bella Vita Lecce 2
We stayed three nights at Chiaraâs place and really enjoyed our stay. The apartment is very well locatedâjust a few steps from the old town, with plenty of restaurants and cafĂŠs nearby. What we loved most was the terrace. We really enjoyed having lunch there (highly recommend grabbing takeaway pizza from Il Pizzicotto!) before heading out to explore the city. On our last day, we rented a car and had no trouble finding a parking spot close to the apartment. As noted in the listing, the apartment is on the third floor and accessed by stairsâabout 70 steps in total. Itâs a bit of a climb, but it definitely helps you stay active during your stay! We would definitely stay in the apartment again. Recommended.
Apartment rentals with a hot tub

Charming apartment, heart city
Nieves was wonderful. She went way out of her way to make us feel welcome. She even volunteered to go shopping for us, since we arrived late in the evening!! When the hot water heater stopped working, she and a technician came out the same day to resolve the issue. When we locked ourselves out of the apartment she made a special trip to provide us extra keys. She is such a nice lady. The apartment was spacious and comfortable. The private courtyard was quiet and peaceful. The bed was comfortable. The linens were pressed. If we ever return to Lecce, we will stay here again.

Luxury Corso Italia - Vista Mare (Sea View)
We had an amazing stay at the apartment. It was exactly as we wanted. Clean and tidy everywhere. Great garage for the car. It was nice that the host had put out various snacks and cold drinks in the fridge. We also received good help with booking, for example, a taxi if we were going out to eat or shop in the old town. Very happy with the stay đ

Wp Relais Tangerine Mint
Itâs a very nice apartment block, thereâs 6 units in total, the location suited our trip, we were greeted by a lovely lady called Lucia who showed us around and made us feel very welcome. Our apartment was beautiful and quiet, very well equipped. I would recommend getting a top floor apartment as the bottom apartment we stayed in was noisy from people walking or moving chairs upstairs. My only other recommendation is that the second bedroom be fitted with a blind as the light shines through, this didnât worry us but might others. We throughly enjoyed our stay and will still recommend you staying.

Trilo CorsoItalia 24 Garage Wifi All in-VisVacanze
Very large, well-appointed apartment. 3 bathrooms for 2, it was fantastic đ Quiet residence, direct access from the apartment to the parking lot, beautiful terrace 30 min walk to Gallipoli beach or 5-10 min drive to quiet beaches I recommend it.

Superior Double Room in Borgo del Salento
Simply paradise: we chose this stop in Morciano di Leuca to get closer to southern Puglia, without really knowing what to expect⌠and it was just wonderful! Hosted by Giulia, everything went extremely well! The services of this Airbnb are EXCEPTIONAL: the beautiful room, the delicious breakfast, the very well maintained jacuzzi, the nearby village is very pretty with good restaurants⌠+ we were a 10-minute drive to the beaches called "Maldives of Salento". In short, we recommend it ++++++ Worth a 5-star hotel! Grazzie mille Giulia for this timeless moment, it was great đ¤Š

SEA DOOR APARTMENTS - Blue, terrace and whirlpool
great location, short walk to beach and town but away from the chaos of the town. availability of on site car parking (additionally paid) was incredibly helpful.

Salento, typical, independent, with terrace
Happy to have chosen this home for my month in Salento! Availability and fantastic courtesy for check-in and check-out. Tastefully furnished and complete house both in the kitchen and in the rest of the furniture as well as very clean! Fantastic location for touring the lower Salento. Thank you for everything! Monica has always made herself available to resolve my every request! Hello and helpful! Thank you so much to you too!

Mae Apulian Rooms 67, Puglia
Gina and Antonella are really very professional They are very responsive and always asking you if everything is going well and if nothing is missing. He really sums up all the necessities for an enjoyable stay Their apartment and really full of beauty and exactly in the description of their listing on RBNB The cleanliness of the apartment and really of all excellence as well as the sleeping and the bathroom My stay was very pleasant I highly recommend them if you want a pleasant stay A huge thank you to Gina and Antonella
Quick stats about flat rentals in Sant'Isidoro
Total rentals
30 properties
Nightly prices starting at
âš1,727 before taxes and fees
Total number of reviews
180 reviews
Family-friendly rentals
20 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Wifi availability
10 properties include access to wifi
Destinations to explore
- Family-friendly rentals Sant'Isidoro
- House rentals Sant'Isidoro
- Rentals with outdoor seating Sant'Isidoro
- Pet-friendly rentals Sant'Isidoro
- Rentals with a washing machine and dryer Sant'Isidoro
- Rentals with a patio Sant'Isidoro
- Smoking-friendly rentals Sant'Isidoro
- Rentals with beach access Sant'Isidoro
- Flat rentals Apulia
- Flat rentals Italy
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Salento
- Spiaggia Torre Lapillo
- Spiaggia Di Pescoluse
- Punta della suina
- Togo Bay la Spiaggia
- Lido Bruno
- Frassanito
- Lido Mancarella
- Alimini Beach
- Spiaggia Torre Mozza
- Lido Le Cesine
- Spiaggia della Punticeddha
- Zeus Beach
- Torre Guaceto Beach
- Spiaggia Baia Verde
- Agricola Felline
- Porto Selvaggio Beach
- Spiaggia di Cala Casotto