
Guest house holiday rentals in Mount Pleasant
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Top-rated guest house rentals in Mount Pleasant
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Family-friendly guest house rentals

Island Oasis—Near Downtown
Apartment was very clean and great location between the beach and downtown Charleston.

Charleston's Coolest Neighborhood
The accommodations and location were perfect. West Ashley has a great vibe and good restaurants within walking distance. It's an easy 15 minute drive to downtown Charleston. Would definitely recommend this place to others.

Bungalow Under The Oaks
My husband and I enjoyed our stay at Bungalow Under the Oaks. The space was clean and cozy, good for two people and a small dog. We enjoyed the fenced in yard and short drive to the beach and restaurants.

Green Garden Studio @greengardenstudio2017
This was the cutest above garage studio. It is very well done, clean and comfortable. The property is very well maintained- we would definitely stay here again! The AC was not working properly when we arrived but Holly responded immediately and got it working. Highly recommend!!

Liz Lane Cottage- entire guesthouse
Our stay was amazing! Brooke was a fantastic host who always responded quickly and was very friendly whenever we saw her or her family. When we were caught in poor weather, she messaged me and gave us umbrellas so we could stay dry during our trip. A great experience and we all hope to stay here again!!

Romantic Beach Style Cottage close to everything!
Clean & conscious hosts! Mindful of needs that may crop up, lovely home & family. Flexible! Perfect oasis away from the bustle of Charleston.

Mother in Law in James Island Riverland Terrace
This was a very cute and quiet place. It is in the backyard of the host and the host were quiet. We felt very safe and it was nice parking in the driveway and not the road. The location is perfect. It is easy and quick to get to about anywhere you want to go. There is a very cute movie theater and pizza place down the road.

Private waterfront apt in the oaks
This is my 2nd time staying & I couldn’t recommend their property enough. Nancy and Joe’s home is beyond gorgeous. I can’t wait to come back! So many great local restraunts & so peaceful on their dock! We saw so many dolphins again!
Guest house rentals with a patio

Quaint Cottage Studio in Ashley Forest (Avondale).
Great place for an individual or couple to use as homebase when visiting Charleston. Has just what you need for a weekend.

Coastal Charm: Village Hideaway
Cannot say enough about this beautiful little cottage. Gorgeous interior and very cozy. Most comfortable bed I have ever slept on, I need to ask what it was! Great location and neighborhood and very easy to get to every thing. Would highly recommend. Thanks so much!!

Spacious 1 bedroom cottage in Avondale
My partner and I really enjoyed staying at Derek and Sarah’s guest house cottage in Avondale. Even though it was located in a suburban area, we found the cottage feeling quiet and secluded once inside. The interior was cozy, the bed was comfortable, and the kitchen very usable to cook some of our meals. We drove to Charleston, and we found the parking space easy to use and clearly marked. Derek and Sarah were very friendly and responsive with any questions we had. With a car, it was an easy drive to our visit to Folly’s Beach, our carriage ride in the French Quarter, shopping at the Charleston City Market, the harbor area for our sunset cruise, the Magnolia Plantation and Gardens, the Charleston Tea Garden, and a lot more. It was a perfect launching pad for a really memorable trip.

Driftwood Cottage
Very clear and simple instructions, would stay here again!

My Happy Place
This was mine and my wife's first time in the Charleston area. I highly recommend this host, we have nothing but great things to say. the ability to check in early, the recommendations to food, activities and places to see, the comfort of the home and the thoughtfulness of having them leave a beautiful note and a bottle of bubbly for us due to our 8 year anniversary. I couldn't have asked for anything else. Thank you very much for everything. I would definitely stay here again.

The Violet Villa w/no cleaning fee
I didn’t want to leave! The description was accurate, but this community was more adorable than we ever imagined! Absolutely awesome and convenient! The hosts went above and beyond, and I’d stay here again and again. Super affordable and definitely one of our top Air BnB experiences to date.

The James: “Tiny” Home b/w Downtown & Folly
If I could give this stay 10 stars, I absolutely would! From the moment we arrived, everything was beyond perfect. The space was spotless, beautifully designed, and full of thoughtful touches that made it feel like a dream getaway. Every corner was photo-worthy — seriously, bring your camera because you’ll want to capture it all! The host was immaculate — kind, responsive, and truly went above and beyond to make us feel welcome. You can tell so much care and intention went into every detail of the home. It felt like stepping into a Pinterest board, but better! We made memories that will last a lifetime and honestly, we couldn’t have asked for a better experience. If you’re lucky enough to stay here — take it! You’ll leave refreshed, inspired, and already planning your next trip back. 🌟✨

Cozy Cottage! 5 mins from Kiawah!
My husband and I thoroughly enjoyed our stay in Lucy’s super cute cottage. It was clean, well appointed, and with the perfect amount of space for a couple. Although we didn’t get a chance to try it out (a little too chilly), the outdoor bathtub was a charming feature, in addition to the other outdoor spaces available. We loved the close proximity to the beach and to downtown Charleston. We felt very comfortable and rested really well. We would absolutely come back to Lucy’s cottage, and I’m sure you will feel the same way!
Guest house rentals with a washing machine and dryer

Peaceful Garden Cottage Retreat
This was the perfect home base for our time in Charleston. It was conveniently located, spotless, and very peaceful. So much thought went into making our stay pleasurable. Looking forward to our return trip!

Cozy Cottage w Games, Firepit, Grill, and More!
This airbnb is really cute! My friend and I enjoyed our stay. The guest house is so charming. We felt very comfortable staying there. The location was perfect, only 15 mins to downtown Charleston and less than 30 mins to get to several different beaches. I would recommend this place for anyone visiting Charleston that wants a cozy, quiet airbnb :)

Private Coastal Cottage-Near Beaches & Charleston!
Thank you again for hosting us. The place was in a perfect location, and you all were very accommodating. Great storage if bringing a boat down, and Jaime and her husband are very welcoming. Would recommend this place to all

James Island "La Casita" Nestled btw Beach & City
We enjoyed our stay so much! The space was very clean and neat. I quick drive to the beach and to the city! The James Island area was amazing! We will definitely stay again if we are in the area!

Summerville’s Tiny Oak Hideaway
Our stay in Summerville was wonderful. I loved being able to walk out our door to take a walk downtown or to the park. It was such a restful weekend away.

Charming Guest Cottage in Old Mount Pleasant, SC
Kari’s guest house was perfect for our quick weekend getaway to Charleston. We were able to hop in the car and get downtown in about 10 minutes, shoot to the beach in 15 and walk to Pitt Street bridge and back for a nice long walk in the morning. The space was clean and check in/out instructions were clear. Mike offered us bikes to use and even gave us chairs for the beach. Such a great weekend and we will definitely be back!

Serene Location - Next to Hampton Park: Haven Hom
Lovely place to stay in Charleston as it's in a residential neighborhood which was very quiet and peaceful. Within walking distance to a few restaurants and the park. We loved having the easy parking! The place is clean and comfortable for a couple and we enjoyed all the living spaces. I appreciated there were no heavy cleaning odors as I'm sensitive to smells/scents. The kitchen was well designed and we put it to use! I really appreciated recommendations for downtown restaurants that could accommodate my food allergies. Seems to be well managed and maintained. We hope to come back!

The Guesthouse at Old Orchard
Spent four nights with a friend in Brandy and Bill’s wonderful guest getaway and wish we could have stayed many more nights. Very clean and well appointed space — the kitchen had everything you need (and then some). Bathrooms were spacious and provided towels and washcloths. Beds were comfortable and there is so much space in this guesthouse. It’s in a quiet neighborhood and the property is very relaxing too. Brandy has created a cozy home away from home and we hope to return again. So many nice well appreciated touches. It’s perfectly located in the area too — so close to many of the attractions and also very close to grocery stores and restaurants. Highly recommend with no reservations!
Quick stats about guest house rentals in Mount Pleasant
Total rentals
50 properties
Total number of reviews
6.3K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wifi availability
50 properties include access to wifi
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- Hunting Island State Park Beach
- Sullivan's Island Beach
- Middleton Place
- Hampton Park
- The Golf Club at Wescott Plantation
- James Island County Park
- The Charleston Museum
- Harbor Island Beach
- Yeamans Hall Club
- Shem Creek Park
- Angel Oak Tree
- Waterfront Park
- Seabrook Beach
- Gibbes Museum of Art
- White Point Garden
- Morris Island Lighthouse
- Isle of Palms Beach
- Hunting Island Beach
- The Beach Club
- Seabrook Island Beach
- Driftwood Beach
- Cougar Point Golf Course
- Deep Water Vineyard
- Whirlin' Waters Adventure Waterpark
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