Guest house holiday rentals in Mount Pleasant
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Mount Pleasant
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Mount Pleasant
Family-friendly guest house rentals
Guest house in North Charleston
4.94 out of 5 average rating, 346 reviewsCozy Park Circle, Charleston Guest House
8–15 Dec
Guest house in Mount Pleasant
4.85 out of 5 average rating, 219 reviewsClose to beach , downtown and Shem creek
29 Oct – 5 Nov
Guest house in Charleston
4.93 out of 5 average rating, 708 reviewsCharleston's Coolest Neighborhood
13–20 Aug
Guest house in Summerville
4.98 out of 5 average rating, 643 reviews★Delightful guest house near historic plantations★
6–13 Apr
Guest house in North Charleston
5.0 out of 5 average rating, 111 reviewsThe Park Circle Clerestory Studio Guest House
19–26 Jun
Guest house in Summerville
4.94 out of 5 average rating, 212 reviewsNina's Cottage -Historic Downtown Summerville
14–21 Aug
Guest house in Ridgeville
4.82 out of 5 average rating, 213 reviewsPond House Bungalow at Natural Gathering Grounds
26 Aug – 2 Sep
Guest house in Charleston
4.91 out of 5 average rating, 648 reviewsIsland Oasis—Near Downtown
21–28 Oct
Guest house rentals with a patio
Guest house in Charleston
4.93 out of 5 average rating, 172 reviewsQuaint Cottage Studio in Ashley Forest (Avondale)
6–13 Jan
Guest house in Charleston
4.98 out of 5 average rating, 123 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
24–31 Oct
Guest house in Johns Island
4.91 out of 5 average rating, 105 reviewsCozy Cottage! 5 mins from Kiawah!
2–9 Oct
Guest house in Charleston
4.97 out of 5 average rating, 127 reviewsStudio Apartment Minutes to Downtown Charleston
25 Mar – 1 Apr
Guest house in Mount Pleasant
4.89 out of 5 average rating, 19 reviewsAdorable guest house with private backyard/patio
13–20 Oct
Guest house in Mount Pleasant
5.0 out of 5 average rating, 27 reviewsCoastal Charm: Village Hideaway
14–21 Dec
Guest house in Mount Pleasant
4.95 out of 5 average rating, 74 reviews*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse
4–11 Sep
Guest house in Hanahan
4.99 out of 5 average rating, 77 reviewsThe Violet Villa w/ no cleaning fee
26 Aug – 2 Sep
Guest house rentals with a washing machine and dryer
Guest house in Charleston
4.98 out of 5 average rating, 244 reviewsDetached Guest Suite
19–26 Nov
Guest house in Summerville
4.97 out of 5 average rating, 217 reviewsTiny Oak Cottage in Historic Downtown Summerville
26 Dec – 2 Jan
Guest house in Charleston
4.99 out of 5 average rating, 142 reviewsLarge Guesthouse with Private Dock & Marsh Views
16–23 Oct
Guest house in Charleston
5.0 out of 5 average rating, 216 reviewsJames Island "La Casita" Nestled btw Beach & City
8–15 Oct
Guest house in Charleston
4.9 out of 5 average rating, 548 reviewsCute, Cozy, Charleston Cottage
14–21 Sep
Guest house in North Charleston
4.94 out of 5 average rating, 111 reviewsNewly Renovated Studio in Park Circle
17–24 Jul
Guest house in Charleston
5.0 out of 5 average rating, 144 reviewsThe Guesthouse at Old Orchard
20–27 Oct
Guest house in Charleston
4.99 out of 5 average rating, 206 reviewsRedesigned suite! 12min to city, pet-friendly
30 Sep – 7 Oct
Quick stats about guest house rentals in Mount Pleasant
Total rentals
60 properties
Popular amenities
Kitchen, Wifi and Pool
Wifi availability
60 properties include access to wifi
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Family-friendly rentals
10 properties are a good fit for families
Total number of reviews
5.7T reviews
Destinations to explore
- Savannah Holiday rentals
- Hilton Head Island Holiday rentals
- Kiawah Island Holiday rentals
- North Myrtle Beach Holiday rentals
- Tybee Island Holiday rentals
- Folly Beach Holiday rentals
- Surfside Beach Holiday rentals
- Hilton Head Holiday rentals
- Beaufort Holiday rentals
- Atlanta Holiday rentals
- Charleston Holiday rentals
- Myrtle Beach Holiday rentals
- Guest house rentals United States
- House rentals United States
- House rentals Myrtle Beach
- House rentals Charleston
- Guest house rentals Charleston
- Guest house rentals Savannah
- House rentals Savannah
- House rentals South Carolina
- Guest house rentals South Carolina
- Rentals with pools Mount Pleasant
- Villa rentals Mount Pleasant
- Rentals with outdoor seating Mount Pleasant
- Rentals with a washing machine and dryer Mount Pleasant
- Rentals with a patio Mount Pleasant
- Beachfront rentals Mount Pleasant
- Townhouse rentals Mount Pleasant
- Rentals with an EV charger Mount Pleasant
- Apartment rentals Mount Pleasant
- Pet-friendly rentals Mount Pleasant
- Fitness-friendly rentals Mount Pleasant
- Rentals with a hot tub Mount Pleasant
- Luxury rentals Mount Pleasant
- Family-friendly rentals Mount Pleasant
- Flat rentals Mount Pleasant
- Monthly Rentals Mount Pleasant
- Rentals with breakfast Mount Pleasant
- Rentals with beach access Mount Pleasant
- Waterfront rentals Mount Pleasant
- Rentals with a kayak Mount Pleasant
- Private suite rentals Mount Pleasant
- Rentals with a fireplace Mount Pleasant
- House rentals Mount Pleasant
- Rentals with a firepit Mount Pleasant
- Family-friendly rentals Mount Pleasant
- House rentals Charleston County
- Guest house rentals Charleston County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom