Holiday rentals in Byron

4.93 out of 5 average rating, 162 reviews

Flat in Rochester

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

5 out of 5 average rating, 45 reviews

New! MN Comforts The Heart 4Bd/2Bth, 12min to Mayo

Welcome to MN Comforts The Heart! Are you here for work or leisure, or want to feel comforted after a Mayo appts? 12 min to Mayo Clinic, Wifi, work-station, ROKU/Smart TVs, and a fireplace in the family room. We offer a 2nd home feel. Near stores. Split-level, chill, and quiet, thoughtfully designed to cater to your needs, ensuring a comfortable, enjoyable stay. A blend of traditional & modern styling in a tranquil home, with fun opportunities for family & friends. Partially fenced backyard.

4.99 out of 5 average rating, 155 reviews

NEW: Renovated rambler with ramp - no stairs!

• Enhanced cleaning protocols due to COVID • Main floor living w exterior ramp for easy access on Mayo Clinic stays • Fully renovated house in winter 2022 • 3 bedrooms w queen beds • Fully stocked kitchen w dishwasher, Keurig and k-cups • Main floor living room w sectional and smart TV • Huge basement w sectional, TV, kids toys • Free garage & driveway parking • High-speed wifi for work/streaming • Central AC & furnace w thermostat you control • Main floor bath tub & lower level walk in shower

4.97 out of 5 average rating, 118 reviews

Home in Kasson

Home Sweet Minnesota

A few days or a few weeks away from home? Let us provide a comfortable and cozy get away in this turn of the century, two story home. Located in a quiet neighborhood with off-street parking, this property boasts large rooms, original hardwood floors and woodwork, a full kitchen, and laundry. The large, fenced in backyard, complete with playground and sandbox, makes this a child friendly space. The front porch and back patio provide outdoor room to grill, picnic, or just relax in a lawn chair.

4.92 out of 5 average rating, 248 reviews

Home Calls the Heart- 10min to Mayo

1/2 block from HWY 52, serene and peaceful split level home. 10 min to Mayo Clinic & St. Mary's Hospital. Fully furnished, convenient and ideal for families and professionals for the home away from home feel. Luxury Sheets & Posturepedic beds. Reasonable Mall of America drive. Fully equipped with various kitchen appliances and utensils. Minutes to parks, groceries, Walmart, Target etc. Wifi, Roku Smart TV & cable. Phone call away if you have any issues while staying at our charming home.

4.93 out of 5 average rating, 160 reviews

Flat in Rochester

Home for the Traveler, a walk to St. Mary's

This place is located near the heart of Rochester, within blocks of St. Mary's hospital, very peaceful, cozy and private. A lower-level unit in an older home, plenty of windows and light, and includes a gorgeous bedroom with a fireplace, a full kitchen, a reading room, and a clean, updated bathroom. This home is also close to the Apache mall, the Canadian Honker and other local restaurants, coffee shops, and the walking/biking trail system. There is also Wi-Fi, laundry, and parking on-site.

4.98 out of 5 average rating, 98 reviews

Pine Cove Cottage under 5 miles to Mayo

Sun filled one room cottage w/everything you need for your short or long stay. Wether it’s a get away or a visit to Mayo Clinic. We have two cottages side by side for you to enjoy. One is the main cottage with everything you need, sleeps 2. The other is a bunkhouse for sleeping. There is no bath or kitchen in the bunkhouse. It has two recliners, a tv, and a daybed. The property is 40 acres of trees, walking paths, post & beam pavilion, 2 fishing ponds all enjoyed on your own private deck.

4.87 out of 5 average rating, 343 reviews

Mayo Downtown's Prairie Home Retreat

Nestled in a serene corner, this home offers a perfect blend of tranquility and accessibility; being near the Mayo campus and Rochester's key attractions. Enjoy comfortable beds, a well-appointed kitchen, and a fenced yard with patio gardens. It's an excellent spot for family bonding, featuring three smart TVs, rapid Wi-Fi, and a variety of indoor and outdoor entertainment options. We strive to accommodate flexible check-in/check-out arrangements whenever feasible. Rollator accessible.

4.97 out of 5 average rating, 242 reviews

Flat in Rochester

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

4.95 out of 5 average rating, 167 reviews

Home in Stewartville

"Walden Pond" Adventure Amidst 44 Private Acres

Embark on your own "Walden Pond" adventure and be at one with nature. Each season brings its own magic: the fiery colors in fall, crunching through snow in the winter, new life in spring, and sports and activities in the summer! The 2000 s.f. log home known as 'The Bungalow" offers romantic fireplace, 2 bedrooms, 2 baths, office/bedroom + huge entertainment room. Easy drive from Rochester and all roads clear in winter. Feel safe from current coronavirus . See more info below.

4.97 out of 5 average rating, 227 reviews

Guest house in Rochester

Hygge House | A Cozy Guesthouse

The Hygge (pronounced hyoo·guh) House is a tiny taste of Scandinavia in Southeastern Minnesota. What is Hygge? In short, it's a Scandinavian way of living that focuses on hunkering down and creating a safe, comforting and warm place to while away. My husband and I hand built the Hygge House with your comfort in mind. We love being cozy and having space to spend together so when the opportunity arose to renovate our studio, we wanted to share it!

4.98 out of 5 average rating, 149 reviews

Apartment in Rochester

Cedar Loft is a tranquil retreat

If you are looking for a quiet retreat w/private entrance outside the city, you are home. Trees are outside every window with palpable serenity yet is still an easy ten-minute drive to downtown Rochester. This is a family-friendly place with crib and changing table. This is not a party house. It has a kitchenette so we will provide information to restaurants and grocery stores within 5 minutes.

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Other great holiday rentals in Byron

Private room in Rochester

4.95 out of 5 average rating, 415 reviews

Magical Nest

MicheleRating, 5 stars1 week ago

We love staying at the Magical Nest. It is beautiful, peaceful and comfortable. Greg and Yvonne are perfect hosts.

4.84 out of 5 average rating, 19 reviews

Home in Byron

Cozy Duplex Unit 10 minutes to Mayo Clinic

MarkRating, 5 stars7 months ago

Great place to stay! Would definitely stay there again!

Private room in Rochester

4.98 out of 5 average rating, 120 reviews

Cozy home 1 bedroom & bathroom, w/no cleaning fee

SherryRating, 5 stars2 days ago

This was a great place to stay. Jacqueline was very responsive to any email and was very welcoming. I had to leave very early and she was up to say thank you and goodbye. Lovely home and yard and absolutely wonderful and gracious host and hostess.

5 out of 5 average rating, 7 reviews

The Wander Inn/ Cat 40+ yrs in Healthcare

LanaRating, 5 stars2 weeks ago

I believe Cat has one of the most affordable prices in Rochester. Cat greeted me at the door, was super kind, and anytime I texted, she responded within 30 minutes if not sooner. Cat's location is conveniently less than 15 minutes away from Mayo Clinic as well! The place was identical to what was pictured, and I was very satisfied with Cat's hospitality. I will make note that the bed in the bedroom is firm, so for my preference I do prefer softer beds.

5 out of 5 average rating, 6 reviews

10 min to Mayo - Recliners - Jacuzzi - No Stairs!

JeannineRating, 5 stars1 month ago

We chose to stay at Bridget’s house for a month long recovery from surgery at Mayo. Knowing that things like the lift recliner and the tub would be helpful after surgery and help with recovery the floor plan ease of everything was really appreciated. It was quiet and watching the backyard wildlife and flowers made for a lovely recovery. We chose the location knowing it would be a few minutes from Mayo but having a grocery store around the corner and a few more stores minutes down the road was perfect. It was away from the super busy traffic close to the hospital and quiet which matched what our backyard at home was like too. Communication was wonderful and she always responded quickly. Will love staying here again in the future.

4.94 out of 5 average rating, 175 reviews

The BEST Stay in Town: See Pics+Reviews to Believe

KatieRating, 5 stars2 weeks ago

This was my second time staying at this house, for medical reasons, and I loved both times! It was so homey and comfortable! Nice and quiet for my recovery from surgery and easy access to get in and out of. Would definitely recommend this location to others!