Guest house holiday rentals in Pima County

Find and book unique guest house rentals on Airbnb

Top-rated guest house rentals in Pima County

Guests agree: these guest house rentals are highly rated for location, cleanliness and more.

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Top guest favourite

Guest house in Tucson

4.98 out of 5 average rating, 594 reviews

TREAT GUEST HOUSE Private, Quiet, Comfortable

The entire guesthouse is in the centrally historic Sam Hughes neighborhood (527 N Treat Ave). Great community with lots of restaurants and markets nearby (4 min to Wholefoods). The host, a Swiss Photographer & artist, designed every amenity to enhance your vacation or business trip in Arizona's gem of a city. You won't want to leave from its practical kitchen to its richly tiled shower and memory foam bed. This unique accommodation will become one of the highlights of your Southwestern adventure

Top guest favourite

Guest house in Tucson

4.96 out of 5 average rating, 371 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favourite

Guest house in Tucson

4.96 out of 5 average rating, 852 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (1-19-2024) "59 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the Eucalyptus Suite Airbnb and the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Top guest favourite

Guest house in Tucson

4.99 out of 5 average rating, 334 reviews

Tranquil Bears Path Casita

This Property is truly a unique oasis in the desert! It is one of the few urban areas in Tucson that offers you the best of both worlds! A place to come home to and enjoy the quiet nights, plentiful stars, and walks among the the numerous Saguaros, Mesquite and Desert Pine trees. All while being right in the heart of Tucson's East side just minutes from shopping and restaurants! Our extraordinary place is close to Mt Lemon, Sabino Canyon, hiking, running, biking trails and riding stables.

Top guest favourite

Guest house in Tucson

4.96 out of 5 average rating, 798 reviews

Private Tucson Desert Guest House Getaway

This guest house is a pleasant desert retreat in Northeast Tucson, nestled on a large property with spectacular views of the Catalina Mountains. Minutes from from Sabino Canyon, Mt. Lemmon, and close to sumptuous dining. Guests will enjoy a recently space which includes a kitchenette complete with a microwave, coffee-maker, toaster oven, refrigerator, and more. Large bathroom and closet. Also available are a pool, BBQ grill, outdoor seating, and play yard. Laundry available upon request.

Top guest favourite

Guest house in Tucson

4.99 out of 5 average rating, 211 reviews

Cozy Mountain Retreat w/ Hot Tub

Come visit our small horse ranch in NW Tucson! Tucked into the foothills of the Santa Catalina Mountains, you’ll enjoy great views, and slightly cooler temperatures. You'll be close enough to town to have access restaurants,shopping, entertainment, etc, yet you'll have unlimited access to hiking and mountain biking right out our gate. * Not suitable for children under 12yrs. **This is a smoke-free property, sorry, no exceptions. *you must be able to climb a small flight of stairs*

Top guest favourite

Guest house in Tucson

4.99 out of 5 average rating, 363 reviews

Time Capsule in the Sonoran Desert

Time Capsule is a unique experience in an space age module dropped in the middle of an 11 acres desert sanctuary and sculpture park, adjacent to the Saguaro National Park. Enjoy the quietness of the desert in a safe environment located at just 35 minutes from downtown Tucson. Because of the refinement of the interior design we cannot accept any pet, service animal, nor children in the Time Capsule. Please note that check in is in person only and not later than 10:00PM. No exception!

Guest favourite

Guest house in Tucson

4.89 out of 5 average rating, 236 reviews

Newly Constructed Downtown Guesthouse

This newly constructed, spacious guest house has an open floor plan with a loft bedroom featuring the most cozy queen-sized bed. The bathroom has a soaking tub and there’s an outdoor shower too. There’s a large gated yard and three porches on which to enjoy a morning cup of coffee or tea. Located in the coveted Dunbar Spring neighborhood, the home is walking distance to the University of Arizona, 4th Ave, downtown, lots of coffee shops and restaurants and the Warehouse Arts District.

Top guest favourite

Guest house in Tucson

4.98 out of 5 average rating, 461 reviews

The Southwest Knest

Cozy and charming, this private guest house sits in the heart of Tucson and makes a perfect home base during your visit to the Southwest! Studio layout is spacious and relaxing for 2. Fully equipped kitchen, bathroom with walk-in shower, Ghostbed mattress, and comfortable work space/fast wifi for those of you working remotely. Easy access to airport, U of A, Saguaro NP, shopping, and hiking trails. Coded entry makes it a breeze to come and go, no shared keys. Come rest at the Knest!

Guest favourite

Guest house in Tucson

4.97 out of 5 average rating, 157 reviews

The Coop- Luxury guest house with ideal location

This luxury guest home was originally a chicken coop for a farmer over 60 years who owned the majority of the land in the area. With an addition and a complete renovation, we have designed this for the perfect vacation rental ideally located in Tucson. 15 minutes to Banner and the U of A. 10 minutes to Oro Valley or the freeway. The stylish guest home is separated from our home and designed with privacy in mind. Enjoy this brand new house for your stay with experienced hosts.

Guest favourite

Guest house in Tucson

4.94 out of 5 average rating, 515 reviews

Central and Stylish Midcentury Pool House

Our beautiful adobe pool house is a Tucson gem. Comfortable queen bed, fireplace, and stylish modern furnishings with large windows looking out to trees and sparkling pool. Vaulted ceilings and natural light make for a restful space. Located in historic Jefferson Park, it’s a midtown oasis close to the UofA and two blocks from the UMC/Banner Medical Center. Midtown/University location allows for convenient access to all of Tucson. *Newly improved high speed WiFi 11/1/2021

Top guest favourite

Guest house in Ajo

4.99 out of 5 average rating, 211 reviews

Cozy hideaway cottage in historic Ajo

Stay in a cozy, very private, window filled 500 sq. ft. hideaway cottage that is located on the property of a historic Ajo home. Located just 4 blocks from the gorgeous Spanish Revival town plaza, you can walk to Ajo's Visitors Center, art galleries, restaurants, library, and coffee shop or you can drive a mile to the Ajo Scenic Loop to savor and hike a portion of the pristine Sonoran Desert that rivals Organ Pipe Cactus National Monument. Let me welcome you to Ajo!