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Guest house holiday rentals in Panama

Find and book unique guest house rentals on Airbnb

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Popular amenities for guest house rentals in Panama

Family-friendly guest house rentals

Top guest favourite
Guest house in Nueva Gorgona
4.99 out of 5 average rating, 72 reviews

Beautiful Casita-Paradise in Panama, New Gorgona

DavidRating, 5 stars2 months ago
Linda and her husband Russ were wonderful hosts. Linda was great communicating prior to my arrival, and very accommodating when my travel plans resulted in an earlier than expected arrival. Russ even gave me a ride to pick up a rental car at an airport 37km away. Beautiful Casita describes the facility perfectly. The casita itself and the grounds were beautiful, comfortable, and peaceful. If you're planning a trip to the Nueva Gorgona/Coronado area, I highly recommend Beautiful Casita. I will book with them again for sure.
Guest house in Bocas del Toro Province
5 out of 5 average rating, 4 reviews

Las Palmas Casita at Bluff Beach Retreat

MarcRating, 5 stars26 months ago
We really enjoyed our vacation, and we can definitely renommend Bluff Beach Retreat. Karen and Steve were very helpful and took good care of us. The nature and the beautiful sorroundings were amazing. A boat trip with Luis, arranged by Karen, is something you shouldn’t miss out - a fantastic guy:)
Guest house in Coloncito
4.95 out of 5 average rating, 19 reviews

Beautiful Casita-Paradise in Panama, Nueva Gorgona

Dustin And GingerRating, 5 stars19 months ago
Love this place! Comfortable and close to everything. Russ and Linda are great to work with. We will be back!
Guest house in Jaramillo Arriba
4.92 out of 5 average rating, 38 reviews

Casita Caramelo

DavidRating, 5 stars16 months ago
A quiet apartment surrounded by a beautiful garden. The home was very clean, and we felt at home right away. Our host Pam was very welcoming to us. I cook and whatever I reached for, Pam had provided. No scratch teflon, a good set of knives and a sharpener, plenty of dishes and glassware, the list goes on. She was particularly considerate to our privacy (for example, by calling us when she’d have to be behind the house to refill a gas canister) but was always responsive when we’d reach out. And she’s a lovely friendly person too.
Top guest favourite
Guest house in Panamá
4.93 out of 5 average rating, 45 reviews

Private cabin and CasaMomote river, Loma Limón.

IsisRating, 5 stars4 weeks ago
A very nice and nice place. Mrs. Mariel is very attentive to us. At breakfast it made us a bread of Gods, too delicious. We loved everything, we went to the river and relaxed a lot, the place was what we needed right now 🥰🤗
Guest house in Boquete
5 out of 5 average rating, 10 reviews

Vista a Baru

ElliotRating, 5 stars5 months ago
What a magical place! Lily and bob were warm, welcoming, and helpful hosts. We had a couple hiccups along the way and they were extremely responsive in helping us. Their property and the surrounds could not be any more beautiful. We hope to be back soon.
Guest house in Panamá
4.4 out of 5 average rating, 5 reviews

Mochila & Art Family House

AnciaRating, 5 stars104 months ago
Iovanna was very welcoming and friendly upon arrival.
Guest favourite
Guest house in Alto Boquete
4.84 out of 5 average rating, 73 reviews

Sinsonte Accommodation

HelenaRating, 5 stars3 weeks ago
We had a lovely time and highly recommend staying here. We were traveling with our 4-month-old baby and Yadira and her husband were so helpful as well as generous about flexible checkin and check out times, which made such a difference. The apartment felt cozy and tidy, and had all the amenities one could need.

Guest house rentals with a patio

Guest house in Playa Coronado
4.8 out of 5 average rating, 5 reviews

• Coronado Guesthouse Zuramaya •

AnhaRating, 5 stars1 month ago
This is a wonderful little garden casita just steps from the beach! Its location made for great morning walks. It’s tucked away on a side street but walking distance to a few really good restaurants. Janette was a wonderful host; so kind and helpful. I will definitely be back!
Guest house in Torio
4.83 out of 5 average rating, 6 reviews

Cozy cabin w/ Queen Bed & ensuite 10 mn from Beach

SereneRating, 5 stars15 months ago
Los Pinos is nestled among pine trees and palm trees as well as many others. Everything is well shaded for a comfortable experience. My cabina was clean, the bed was comfortable. This is a real bed and breakfast, I was treated to eggs cooked to order, served with “hojaldre” a puff pastry, an authentic specialty. The host Mike is personable and a wealth of information about the area
Guest house in Boquete
5 out of 5 average rating, 4 reviews

Mambú - Lantana guesthouse.

AlexisRating, 5 stars1 month ago
I have had the opportunity to stay in another spot in Boquete and this one from Marissa is 10/10. It has a huge courtyard with green areas, gacebos, and they are building other living areas. Also, the host is very friendly, always attentive to your needs and no matter what time you need. The area is super quiet, so you can rest at ease, and has renewable energy, part of its illuminaria uses solar panels and something important to emphasize is that they use 3 water filters, so it is 100% drinkable and you do not need to buy water. The place has all the dawnings you need and more. Definitely recommended.
Guest house in Bocas del Toro
4.8 out of 5 average rating, 30 reviews

Studio with Pool Near Beaches in Bocas del Toro

CassandraRating, 5 stars2 months ago
Carolina was a very responsive and friendly host. She greeted me and made me feel right at home. I would stay here again.
Top guest favourite
Guest house in Pedasi
5 out of 5 average rating, 31 reviews

A Remote Paradise in nature - Ocean View

DennisRating, 5 stars3 months ago
Dennis was an EXCELLENT host !! From the moment we arrived, his purpose was for us to have a memorable experience ! We are seasoned traveler's, The price included wonderful breakfast every morning. he gave us all the information we requested, in a timely manner. When we come back, we will stay with him. Thank you Dennis and Juan. Our fair well dinner was FABULOUS !! We both highly recommend staying here. until we see you again our friend ! Daisy and Dennis Bush
Top guest favourite
Guest house in Bocas del Toro
5 out of 5 average rating, 9 reviews

Toucan Bay Lodging & Holistic Services

TessaRating, 5 stars3 months ago
Our stay at Jen and Chris’s Airbnb was pure magic. From the moment we arrived, we were surrounded by breathtaking views and the kind of tranquility that only comes with being right on the water. The casita was thoughtfully designed, with a well-equipped kitchen that made cooking easy and enjoyable. Waking up to the sound of the waves and sipping coffee while watching birds flit through the trees was an absolute dream. The water access here is incredible; calm, clear, and perfect for swimming. We spent so much time in and out of the water, just soaking in the beauty of the place. The kids ran wild together from sunrise to sunset, fully immersed in nature, and we loved seeing them so free and happy. One of the highlights of our trip was the massage I received from Jen. I can confidently say it was one of the best massages of my life. It was intuitive and deeply relaxing. It was exactly what I didn’t even know I needed.
Guest house in Torio
4.58 out of 5 average rating, 26 reviews

Olé #2 | Close the beach, restaurants, activities

MikeRating, 5 stars3 months ago
Thank you John, Anita and Team Olé! We had a fantastic time visiting Torio. The cabaña was clean, modern, with A/C and a beautiful semi-outdoor bathroom. The location is central to Torio town, with several restaurants and beach in walking distance. The cabaña is located next to the Olé TexMex restaurant and the food is incredible (we recommend the birria tacos). A special thanks to the team for the excellent customer service and recommendations. John and Anita were even kind enough to drive my partner and I to a local spot to visit the waterfalls that was harder to reach on foot. We 100% recommend visiting this gem of a town for anyone wanting to explore a different part of Veraguas, and Olé is a great place to stay! Thank you again!
Superhost
Guest house in Rio Sereno
5 out of 5 average rating, 3 reviews

The Farmer’s Shack - Pure Nature

AmadorRating, 5 stars15 months ago
The space surrounding the place was so beautiful and the property itself was very cozy. All the perfect spot to go as a couple. Mrs. Edisa and Silvia were very communicative at all times. Instructions were clear. The room is ideal for an intimate moment and disconnect. For now there is no internet for remote work, so you can disconnect to relax. It is an excellent place to share as a couple. I would have liked to stay to live hehe. We rest deeply. The patio is spacious and comfortable. Everything was very clean. I liked going out to the terrace to see the scenery. Just being in the house gives you peace. The terrain is also spacious but steep. Nice atmosphere. Cool during the day, cold at night. Silvia and Edisa always helped and responded quickly. We recommend arriving during the day to find the location well. At night it can be confusing, but we were able to get there without problems with a 4x4 car. The path for a sedan car is very intense.

Guest house rentals with a washing machine and dryer

Guest favourite
Guest house in Panamá
4.83 out of 5 average rating, 29 reviews

Private Guest House in Ancón

RubénRating, 5 stars1 week ago
Mrs. Noris has been the best host I've had in a long, long time. The place was amazing, it was much more than she advertises. The cleanliness, the order, the place with its nature, the kitchen implements, comfortable beds, television and much more, I would return a thousand times. My parents stayed with me and regretted the fact that we could not stay longer. We are all very grateful! In addition, it makes very valuable local recommendations for travelers
Top guest favourite
Guest house in Boquete District
4.95 out of 5 average rating, 22 reviews

Casa Tropical Boquete, Duplex#1 2R /2BR

DanRating, 5 stars1 month ago
The apartment was far better than the pictures led me to believe. Being surrounded by trees, it is very quiet and cool. The apartment is much larger than we thought it would be. There were quiet, secluded seating areas all around the property where we enjoyed the cool breeze and the sounds of birds chirping. Peaceful, calming. Excellent!
Superhost
Guest house in Playa Venao

Modern Casita just a short walk to the beach

LuisRating, 5 stars16 months ago
The person who attended us was Esteban, his attention was incredible and with very good communication, the house was excellent and very well positioned
Superhost
Guest house in La Chorrera
5 out of 5 average rating, 3 reviews

A charming spot in La Chorrera

AjotaRating, 5 stars4 months ago
Cozy house type apartment studio inside a main property. The dining room has terracotta tile floors with comfortable and functional furniture. Its areas are illuminated by natural light and decorated with plants. Located in a very quiet area, outside the center.
Superhost
Guest house in Los Naranjos
4.71 out of 5 average rating, 70 reviews

Alicia's Cabins 1

VeroniqueRating, 5 stars3 months ago
Clean and nice place, fits described bedrooms. Ezequiel was very friendly and helpful. Well placed, a bit further from Boquete but still close and close to the Lost falls that was a great hike. Washington machine was not in the unit but easy to wash clothes asking Ezequiel. Beds were comfortable.
Superhost
Guest house in David
5 out of 5 average rating, 7 reviews

Cozy, quiet and great location!

BlaneRating, 5 stars13 months ago
Staying here was an outstanding experience in more ways than one. This is a good location for exploring other parts of Panama. Look up "Villa del Carmen, David, Panama" on Google Maps to get an idea. Tranquil is a good way to describe the area also. Apt. Isn't big, but is plenty good for 1 or 2 people. Kitchen & sitting areas are outside, with everything you need. If it gets too hot in the afternoon, just take a little siesta inside & you'll be fine. Very relaxing! Lina was an excellent host, & I had the pleasure of spending time with her. The apt. itself is behind the home of a nice, sweet, kind, helpful, generous woman named Amarilis. Get to know her! Amarilis turned a good experience into a great one! We had many good conversations (using Google Translate), she was patient with my lousy Spanish & I enjoyed her company very much. She & Lina helped make my decision to move to Panama an easy one, & I look forward to seeing them both again. Wish I could write more! I highly recommend!
Top guest favourite
Guest house in San José
4.96 out of 5 average rating, 28 reviews

Guesthouse in Punta Barco Resort

BirgitRating, 5 stars1 month ago
A very warm thank you for the mega hospitality! We felt super comfortable and are already planning another visit :-) With your help and tips, it was a great vacation. The family and dogs are all just so lovely! The pool is large and clean, the terrace is almost adjacent to 'jungle' with vultures in the tree, parrots and visit to the large iguana, only Sloth Dieter could not be seen. The sea with private access was soooo warm, a dream! The large pool there is also clean and well maintained. 100% referral ♥
Superhost
Guest house in Jaramillo

Secluded Casita guest house

DiogelRating, 5 stars12 months ago
The guest house is a magical place, tranquility and peace, total connection with nature and vegetation, perfect place to rest, read a book, enjoy a good Boquete coffee or chocolate, a very quiet place to work online, connection stable internet. The guest house has everything you need and if there is something that doesn't, Scott will always be there to see if you need anything during your stay.

Destinations to explore