Apartment holiday rentals in Panama City

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Top-rated apartment rentals in Panama City

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Guest favourite

Apartment in Panamá

4.92 out of 5 average rating, 110 reviews

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES

Spectacular duplex penthouse in Panama's old town, 265 square meters with balconies, private outdoor terraces, it has an interior garden lounge, a dining room, 3 bedrooms (+ sofa bed in studio), recently renovated with a loft concept, unique and comfortable exclusive design, in the best area of the old town, perfect for relaxing and unwinding, kitchen, dishwasher, living room with washing machine, swimming pool, elevator, 24-7 doorman, children who cannot swim are not allowed, a wide variety of leisure activities in the area.

Top guest favourite

Apartment in Panamá

4.98 out of 5 average rating, 42 reviews

Modern Cozy Apt in Prime Location of Panama City

High floor & spacious unit Apt with balcony & great views, located in popular neighborhood Bella Vista , the heart of Panama City. This prime commercial area attracts locals & walking distance to supermarkets, shops, restaurants,entertainment, &metro sta. It's known for being a vibrant area, with a mix of upscale & local options. It offers Free HighSpeed Wi-Fi, Cable & Smart TVs, a Swim Pool, Gym, Office Space & Parking. The building features a Restaurant, Rooftop Bar, spa, cafe & beauty salons

Superhost

Apartment in Panamá

4.92 out of 5 average rating, 48 reviews

Spectacular oceanfront condo, infinity pool

Apartamento familiar para estrenar frente a la cinta costera de Panamá, WI FI 150 Mbps, NETFLIX, PRIME VIDEO, MAX, piso alto, ascensor, aire acondicionado, piscina infinita, parqueadero privado, estación de metro a 5 min caminando funcionado hasta el aeropuerto de Tocumen, centro de lavado, calentador de agua, cocina, excelente vista y ubicación........ IMPORTANTE: durante el mes de Junio de 2025 no hay servicio de gas, por lo tanto no tendrás servicio de estufa, secadora y agua caliente.

Top guest favourite

Apartment in Panamá

5 out of 5 average rating, 19 reviews

Luxury New Modern Condo 1BR Best Location!

➤ Centrally located in San Francisco, one of the best neighborhoods in Panamá City. Enjoy the high floor view from your private Balcony! FREE EARLY CHECK-IN (subject to availability) ★ Close to everything! Walk 5-10 mins to Restaurants, Supermarkets and Multiplaza: the best Mall in Panamá Travel with the comfort of being in your home! in this new, high floor, modern and minimalist full apartment with top of the line appliances, which is great for personal/business or family enjoyment

Top guest favourite

Apartment in Panamá

4.95 out of 5 average rating, 66 reviews

Stylish SeaView Condo w/ Pool & Gym in SF, Panama

Stay in our stylish 120sqm apartment in lively San Francisco, Panama! And relax by the swimming pool or work out at the gym! This fully furnished space offers ocean views, high-speed WiFi, and secure parking. The full kitchen is equipped for all your cooking needs. Each bedroom has a Smart TV and a private bathroom with towels and toiletries. Just a 2-mn walk to supermarkets, 1 km to CC MultiPlaza, and 5 mn to ATLAPA. Expore nearby bars and restaurants for the ultimate experience!

Superhost

Apartment in Panamá

4.88 out of 5 average rating, 49 reviews

Nice apartment with incredible ocean views!

➤ A spacious and cozy apartment with a spectacular ocean view. Located in Coco del Mar, one of the quietest areas of Panama City. ★ Ideal for remote work. ★ A cozy, comfortable, and stylish space, perfect for an urban getaway with family or friends! Building ➤ Amenities: ★ Gym ★ Pool with ocean views High speed 100 MB★ Internet ➤ Located in Coco del Mar | Swimming pool | Explore the city easily | Get around with Uber | Close to the airport.

Guest favourite

Apartment in Panamá

4.95 out of 5 average rating, 102 reviews

Beautiful Apartment 3 guests

Moderno, elegante y cómodo departamento, cerca de todo! Restaurantes, farmacias, supermercados, canchas de padle, a pocos minutos del centro comercial Multiplaza. Totalmente amoblado, 1 recamara, 1 baño completo, walking closet, cocina, sala, área de desayunador, lavadora-secadora y balcón. Para su disfrute, piscina de agua salada en el último piso, gimnasio, espacio de co-working, incluye un espacio de estacionamiento con valet parking.

Top guest favourite

Apartment in Panamá

4.93 out of 5 average rating, 46 reviews

Luxury Apartment & Remodeled on Golf Course

Te ofresco a beautiful apartment in Tucan Country Club & Golf Panama with high speed Wiffi 600MB, surrounded by lush nature and exceptional amenities. Enjoy a free bottle of wine, and ease to be able to rent full Golf or Tennis equipment (Free on a 10 + day stay). Amazing social area, swimming pool, terraces, Gazebo and Gym, Private Club offering Tennis courts, basketball and professional golf court (fee not included), golf shop and restaurant

Top guest favourite

Apartment in Panamá

5 out of 5 average rating, 16 reviews

180° Casco Viejo Views, Pool & Coworking

☆ What our guests are saying: "The view was astonishing." "It is clean, quaint, and cozy." "I truly felt safe, and it was very modern." "No one can beat this treatment Chef kiss". ☆ Early check-in is available! Amenities: ☆ Salt-water pool. ☆ Comfy coworking space with free wifi. ☆ High-speed elevators. ☆ Bicycle rental is available in the lobby. ☆ Parking space (extra fee applies). ☆ Lobby concierge and 24/7 security.

Superhost

Apartment in El Cangrejo

4.8 out of 5 average rating, 40 reviews

Sky Blue Apartment - The Crab

Welcome to the heart of Panama City! This modern and cozy apartment is located in the vibrant area of El Cangrejo, on Eric del Valle Street. Surrounded by convenience stores, restaurants of various nationalities and a lively nightlife, this apartment is the ideal starting point to explore all that the city has to offer. Located on the 19th floor, this apartment offers a spectacular view of Panama’s stunning cityscapes.

Guest favourite

Apartment in Panamá

4.76 out of 5 average rating, 101 reviews

Amanecer - Studio in Casco Viejo

Casa Cielo - Welcome to your home at the heart of Panama City! Your Airbnb is a private studio, offering a great value for a low price, located in the colonial neighborhood - Casco Antiguo - right in the historic center of this buzzing city. The area is filled with rastaurants, bars, museums & churches. The perfect setting for you to enjoy the culture, food scene and night life the city offers

Top guest favourite

Apartment in Panama

4.99 out of 5 average rating, 243 reviews

Patty’s Charming Studio with King bed in Casco

Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen aside from the main living space. It is spacious, comfortable and tastefully decorated!