
House holiday rentals in Santo Domingo
Find and book unique houses on Airbnb
Top-rated house rentals in Santo Domingo
Guests agree: these houses are highly rated for location, cleanliness and more.

Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Colorful Caribbean house in the Zona Colonial
Enjoy a marvelous stay at this gorgeous, colorful and spacious home at the Zona Colonial. Light, airy rooms and amazing private outdoors create a unique caribbean flair. Relax in the tropical garden...refresh yourself with a dip into the tiny pool…dine under the stars or enjoy the amazing view of the San Francisco monastery ruins from the balcony. The famous Plaza de España is a few steps away and all the historical sites, museums, restaurants, cafés and bars are within easy walking distance.

casa bella 3 camas 1 king + 2 twin airport 15min.
Relájate en este espacio tranquilo,elegante y seguro aeropuerto (15 minutos) playas ,calles principales Supermercados cerca (zona súper tranquila segura y muy confortable ) 1–incluimos servicio de lavado y secado 2–wifi 3–Tv Smart 55 sala y 65 hab principal 4–puerta principal inteligente con clave 5–muebles en leather 6– cama principal king size 7–aire acondicionado en la principal 8–parqueo techado y cerrado 9–inversor de Luz 24 horas incluido Soy súper atento con mis huéspedes

San cristobal villa
Brand new large and spacious home in gated property with luxurious pool details and amenities. 4 bedrooms with 3.5 bathrooms including jacuzzi hot tub. Full and modern kitchen with gas stove, oven and large refridgerator. WiFi and cable TV with land line house telephone. Outside includes huge yard and garden with patio and private 2 car garage. 3 balconies with mountain views.and pool view Lots of closet space. Whole property is gated and safe for children and pets.

The Bright Gazcue Suit C Cottage
Este alojamiento sencillo pero encantador te ofrece una experiencia relajante en una ubicación privilegiada: a solo 12 minutos caminando de la histórica Zona Colonial y a tres cuadras del emblemático Malecón, donde podrás disfrutar de vistas al mar, restaurantes, y vida nocturna. Ideal para descansar sin alejarse, nuestro espacio combina serenidad con acceso rápido a los principales puntos turísticos, culturales y gastronómicos. Tu comodidad es nuestra prioridad.

Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Cozy, central and well-equipped place
We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

Ocean Waves, Boca Chica
Enjoy this charming two-story villa, two bedrooms, two bathrooms, sofa bed, a few meters from the beach, in the best most exclusive area of Boca Chica, just steps from the best restaurants: Boca Marina, St Tropez, Neptuno and Pelicano. Enjoy a cozy atmosphere, a finely furnished atmosphere for you and your family to have a wonderful experience. You'll receive a unique place with personalized service so you never miss a thing.

"Peter's Green Villa"
"Si quieres alejarte del ruido de la cuidad y conectarte con la naturaleza, este alojamiento esta pensado para ti, podrás disfrutar con toda tu familia y amigos, de una encantadora villa rodeada de naturaleza y hermosas vistas al horizonte. Un lugar simplemente hermoso donde podrás relajarte y escapar de la rutina diaria." Es para personas aventureras que les gusta la privacidad y tranquilidad de estar alejados de la ciudad!!

Cozy little house in the heart of the Colonial Zone
A cozy 2-bedroom house for 4 people, located in the heart of the Colonial Zone in Santo Domingo, within walking distance of all cultural and tourist attractions. It has 2 comfortable bedrooms and a study with a sofa bed; 2 bathrooms, a nice living room, large dining room, equipped kitchen and a beautiful inner courtyard. Wonderful for vacations and cultural trips, ideal for couples, families, friends, and business travelers.

Charming Colonial House!
Discover this beautiful renovated colonial house with a modern minimalist touch, located 2 minutes from Puerta del Conde and the historic Colonial City of Santo Domingo. Just steps from the Malecón, you'll be in a quiet area but close to restaurants, bars, beauty salons, spas, and supermarkets. Enjoy a comfortable stay in the heart of the city, combining history, modernity, and convenience. Perfect for exploring!

Charming Old City Corner House
This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.
Popular amenities for house rentals in Santo Domingo
House rentals with a pool

House for groups with a pool SDE

PrivatePool - BBQ - Terrace - Excelent for Big Fam

Private Pool, Fast Wi-Fi, A/C, Near Zona Colonial

Royal Villa with a swimming pool in Villa Mella SD Norte.

Hm Tropical Villa-Luxury

Family Villa in Boca Chica

• City Oasis • Luminous House nr Colonial Zone

Family Villa with Pool
Weekly house rentals

Private Jacuzzi Apartment | Central Location

Shulywow Santo Domingo West Luxury Comfort Insurance

House with an excellent location

Entire house for rent, private, Picuzzi

Modern House with Terrace

House near SDQ and Samaná Bus Caribe tours

Beautiful spacious house in a safe residence

Functional apartment 22-2A
Private house rentals

Comfortable house in Sto Dgo Este

Sweet home, 3 A/C, 3 Parking spaces. Av. Jacobo Mujluta

Residential apartment in Boca Chica

Villa between Boca Chica and Juan D. Breakfast included

Sweet 🏡 home

“Your home away from home”

Mariu House

Zona Colonial Large Room, Private Bath & Entrance
Destinations to explore
- Ski-in/ski-out rentals Santo Domingo
- Fitness-friendly rentals Santo Domingo
- Apartment rentals Santo Domingo
- Cottage rentals Santo Domingo
- Rentals with a washing machine and dryer Santo Domingo
- Loft rentals Santo Domingo
- Pet-friendly rentals Santo Domingo
- Farm stay rentals Santo Domingo
- Family-friendly rentals Santo Domingo
- Cabin rentals Santo Domingo
- Rentals with a hot tub Santo Domingo
- Rentals with a cinema Santo Domingo
- Rentals with outdoor seating Santo Domingo
- Beachfront rentals Santo Domingo
- Rentals with an accessible-height bed Santo Domingo
- Rentals with a firepit Santo Domingo
- Guest house rentals Santo Domingo
- Waterfront rentals Santo Domingo
- Rentals with a fireplace Santo Domingo
- Rentals with an EV charger Santo Domingo
- Rentals with beach access Santo Domingo
- Private suite rentals Santo Domingo
- Flat rentals Santo Domingo
- Rentals with pools Santo Domingo
- Rentals with a sauna Santo Domingo
- Hotel rentals Santo Domingo
- Rentals with lake access Santo Domingo
- Smoking-friendly rentals Santo Domingo
- Villa rentals Santo Domingo
- Bed and breakfasts Santo Domingo
- Rentals with breakfast Santo Domingo
- Serviced apartment rentals Santo Domingo
- Rentals with a patio Santo Domingo
- Tiny house rentals Santo Domingo
- House rentals Dominican Republic
- Things to do Santo Domingo
- Nature and outdoors Santo Domingo
- Things to do Dominican Republic
- Tours Dominican Republic
- Nature and outdoors Dominican Republic
- Sightseeing Dominican Republic
- Entertainment Dominican Republic
- Sports activities Dominican Republic
- Food and drink Dominican Republic
- Art and culture Dominican Republic