
Hotel holiday rentals in Panama Canal
Find and book unique hotel rentals on Airbnb
Top-rated hotel rentals in Panama Canal
Guests agree: these hotel rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for hotel rentals in Panama Canal
Family-friendly hotel rentals

3. Apart-Hotel Boutique- Heart of the Old City
Absolutely amazing. Place was spaciouse, clean, well equipped. Location was right in the heart of Caso Viejo and Andres was a true gentlemen our whole stay there. I would highly recommend this place to anyone looking to stay in the heart of Casco Viejo. Dining, entertainment, sight seeing walking all walking distance. truly 5 out of 5 review.

Eco Lodge Garden Room 4, Oceanview Plunge Pool
Lovely and peaceful place to stay on Taboga and would recommend!

6. Beautiful Boutique Apart-Hotel Views & Services
Wonderful Airbnb in Casco. La Isabella Suites was located in the heart of CV. Apartment was very spacious and comfortable. A balcony overlooked a beautiful park. Great stay. Highly recommended!

4. Heart of the Old Town: Boutique Apart-Hotel
This place is gorgeous and has all the amenities. We wish we could have stayed longer. we arrived with a car and had prepaid to park in their small ramp. We thought the car would have GPS but it didn't so we realized we needed SIM cards to get around the country. Rodrigo checked us in and it was five star service from the start. He then walked us to shops until we found and purchased a SIM for our phones. The instructions were in Spanish so he then helped us set up the SIM cards. He did an informal walking tour and showed us some recommended restaurants so we could have dinner. The location is awesome and surrounded by great restaurants and shops in the heart of Casco Viejo. The rooms are gorgeous and the balcony's are fantastic for watching the bustling town. We couldn't recommend this place more!

5. Beautiful Boutique Apart-Hotel-Views & Services
The place was gorgeous and the staff was super friendly, helpful, and attentive. The location couldn't be any better for exploring Casco Viejo.

Eco Lodge Mango Room 3 Queen Plus
I absolutely LOVED my stay! The area is so beautiful and the room was perfect. Every single person working at the hotel was lovely and so helpful, we had great conversations. The owner even picked me up from the port area. I will definitely be back!

1. Boutique Apart-Hotel - Old Town Center
Andres is an amazing host! He was super responsive, very helpful and was extremely easy to communicate and coordinate with. The apartment was exactly as pictured and the location was very close to all the best restaurants and bars. I would definitely come back and stay here again and recommend it for anyone visiting Casco Viejo in Panama City!

Hostal Villa Grande - MIXED DORM 7
I like hostels. You always meet crazy people. This one just adds up. It is sufficient
Hotel rentals with a pool

Double room in Cosy pool hotel near Veracruz beach
The hotel facilities are very well, renovated and cared for and clean. Very friendly with the animals, we are very grateful for that.

Rainforest Suite with Breakfast! 15 min from city
peacefully and beautiful place...

Double Suite-Apartment Hotel Príncipe
Great service and arrival

Private room 2 twin beds
I'd stay there again.

Meryland Hotel
After I got moved to room #120, everything improved for the better and I thoroughly enjoyed my stay at the hotel. The staff was VERY accommodating. They were extremely helpful and did whatever they could to assist me. When I come back next year, I would like to stay in the same room #120. 🙏🏾🇵🇦 Víva Panamá! Arriba Colón! #C3

Queen Room3 and Vida Lotus Retreat & Spa, Limon, PA
Very nice place, with a good view, very friendly Michael with his attention, the dogs were very friendly, the place in general is very quiet and surrounded by nature. Keep in mind that food is vegan. The breakfast pancakes were very good.

In the heart of the city.
My stay at Hotel Mío in Panama City was wonderful. The place is simply unbeatable - it's incredibly located, right in front of the city's most iconic skyscrapers and buildings, offering a spectacular view. The pool on the rooftop is beautiful and perfect for relaxing. Also, breakfast is included and is delicious. The hotel itself is beautiful, modern and cozy; I would definitely always come back to stay here every time I visit Panama. I want to make a special mention to Josué, from the restaurant area, whose attention was excellent and really made my experience even better. I highly recommend this hotel!

Deluxe King, Marinn Place, Complimentary Breakfast
All good
Hotel rentals with a patio

Harpy Eagle Room in Treehouse
We loved the place, very nice and relaxing. The kitchen quite equipped, I would only recommend having a coffee machine and a little more of usencilios or crockery for groups of more than two people.

Eshel Panama Suites, Atlantic suite 04
Great host, beautiful place, great location! Enjoyed the stay!

Taboga Palace Hotel. Beach front English Bouquet
Recommended. It's a great place.

Deluxe Room with 2 Double Beds
excelente lugar super recomendado

Unique | Deluxe | Private Room
a lovely oasis, green and colorful, in the middle of the city :)

Grand Internationa Hotel - King Room
does the job especially if u need a quick room for a layover.. nothing fancy just a room, shower, and food!

Charming Hotel in Casco Viejo Santa Ana Deluxe

Charming Studio w King Bed
Destinations to explore
- Rentals with breakfast Panama Canal
- Hostel rentals Panama Canal
- Rentals with a patio Panama Canal
- Family-friendly rentals Panama Canal
- Rentals with an accessible-height bed Panama Canal
- Serviced apartment rentals Panama Canal
- Rentals with a sauna Panama Canal
- Flat rentals Panama Canal
- Waterfront rentals Panama Canal
- Apartment rentals Panama Canal
- Rentals with an EV charger Panama Canal
- Pet-friendly rentals Panama Canal
- Rentals with a hot tub Panama Canal
- Rentals with a washing machine and dryer Panama Canal
- Family-friendly rentals Panama Canal
- Rentals with a cinema Panama Canal
- Rentals with beach access Panama Canal
- Rentals with a firepit Panama Canal
- Smoking-friendly rentals Panama Canal
- Bed and breakfasts Panama Canal
- Rentals with a kayak Panama Canal
- Rentals with lake access Panama Canal
- House rentals Panama Canal
- Rentals with outdoor seating Panama Canal
- Beachfront rentals Panama Canal
- Rentals with pools Panama Canal
- Fitness-friendly rentals Panama Canal
- Hotel rentals Panama
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom