Holiday rentals in Osborn Medical Center, Phoenix

4.97 out of 5 average rating, 178 reviews

Best Little Guesthouse in Melrose !

Historic guesthouse in the heart of the Melrose District! EV charger! Walking distance to restaurants, bars, coffee shops, the famous Melrose Vintage shops, grocery stores, LA Fitness and more! Want to head downtown to Chase Field, Talking Stick Arena for a game or a show? Campbell Street Light Rail station is only five short blocks away! No need for a car, you can take the Light Rail from Sky Harbor International Airport, save your money for entertainment! Off street parking if you have a car!

4.98 out of 5 average rating, 105 reviews

Spacious Midtown guesthouse with full privacy

Welcome to your private casita (tiny home) in the heart of Midtown. Located right across the street from Starbucks, Buffalo Exchange, and the famous Taco Guild, relax comfortably with vaulted ceilings, a spacious layout, outdoor patio, and a quiet bedroom with a Queen-size bed — perfect for solo travelers or couples. Plus, the Light Rail station is walkable, which goes to Uptown, Downtown, the airport, Tempe, and Mesa. You are only: 7 mins to Downtown 9 mins to the Airport 15 mins to Scottsdale

4.9 out of 5 average rating, 162 reviews

Apartment in Encanto

The Beverly Bungalow 1BR/BA in the 🖤 of Phoenix

Relax & unwind at our mid-century bungalow in the heart of Phoenix. This 1BR/1BA condo will comfortably sleep 2 (up to 4 using an air mattress). Our condo is complete with a full kitchen, cozy living room & dedicated work space for the WFH professional. Also included is a shared pool/hot tub to cool off on those hot summer days. Located in Midtown center to museums, unique bar & restaurant concepts, Chase Field, The Footprint Center - the list goes on. We hope you enjoy all AZ has to offer!

4.96 out of 5 average rating, 106 reviews

Guest house in Willow

Poolside Guesthouse with Private Patio in Midtown

Welcome to the Poolside Guesthouse! Everything has been designed with you in mind to help you enjoy your time in Phoenix! Furniture and fixtures have been selected for your comfort and to help maximize the space. The Poolside Guesthouse has fantastic outdoor spaces for you to enjoy our beautiful weather & offers one of the best central locations with easy access to the airport, shopping, arts district, museums, bars and restaurants. TPT License #21525000 City of Phoenix License #2023-4161

Guest house in Phoenix College

4.97 out of 5 average rating, 1,231 reviews

Private, Sparkling Clean Historic DTPHX Guesthouse

This charming studio guesthouse in the Campus Vista historic district is a fantastic find! Situated in a friendly neighborhood in the heart of Phoenix, this newly remodeled living space is cozy and practical, surpassing many of the similar properties in quality and character. A short ten-minute drive from the Sky Harbor Airport, and located within walking distance to two major bus lines and the light rail, the guests are sure to enjoy the easy access to all the popular downtown destinations.

4.97 out of 5 average rating, 183 reviews

Guest house in Willow

PHX's Modern Midtown Carriage House, Free Parking

Experience the perfect blend of historic charm and modern comfort in the heart of Phoenix's Midtown. Our beautifully designed Carriage House offers a unique guest quarters, complete with a full kitchen, luxurious bedding, and a private patio. Step outside and explore the vibrant neighborhood, filled with local restaurants, shops, and cultural attractions. Book your stay at the Midtown Carriage House today and discover the best of Phoenix living. check out on insta @midtowncarriagehouse

5 out of 5 average rating, 351 reviews

Urban Green House The Garden House

The Urban Green House brings farm life to the urban core. We offer fresh eggs from our backyard hens and gardens for guests to enjoy. We also live green-using solar panels, recycling, and composting. Sarah and Ryan live locally and are available to meet any needs that arise. We are located in a quiet and safe 1950s neighborhood, close to local restaurants, coffee shops, Encanto park, direct access to both the I-10 and I-17 freeways, and only 8 miles from Phoenix Sky Harbor Airport.

4.95 out of 5 average rating, 111 reviews

Apartment in Encanto

Brand New, Modern, Work Friendly 2 Bedroom Condo

Location is in the middle of all the Cactus League Spring Training action. Welcome to our 2 bedroom/1 bathroom home near Downtown Phoenix and 7th Street corridor! Located in an up and coming, urban neighborhood with access to public transit. At our location, you’re never far from your next adventure. We offer a pet-friendly environment, blazing FAST WiFi, onsite parking, a fully stocked kitchen, SmartTV, and more! This is the perfect place to call your home away from home.

4.89 out of 5 average rating, 981 reviews

Cottage in Encanto

Private studio cottage, charming, downtown

This is a 100 year old quaint historic home located in downtown Phoenix area. Encanto Park established in 1935 is right across the street, enjoy the duck ponds, paddle boating, 18 hole Encanto golf course within walking distance, Pool directly across the street during summer only. friendly park and neighborhood! Bikes are available for borrowing. Several restaurants, museum, theatre within 2 miles. Sky Harbor Airport within 7 miles, Highway I17, I10 within 2 miles.

4.96 out of 5 average rating, 535 reviews

Guest house in Phoenix

Uptown Spacious Studio | Resort Style Outdoors

Discover Uptown Phoenix and its vibrant charm! Nestled in the historic district, our property offers a serene escape in the heart of the Valley. This spacious, private studio features a resort-style outdoor retreat, a shared courtyard, a gourmet grill, two outdoor dining areas, and a cozy fire pit to unwind. Inside, relax in a comfortable living room, enjoy meals or card games at the dining table, and retreat to a glamorous bedroom for the perfect end to your day.

5 out of 5 average rating, 208 reviews

Guest house in Willow

Adorable Willo Cottage in Historic Central Phoenix

Peaceful one bedroom cottage in unbeatable location within Central Phoenix. Walking/ biking distance from light rail, restaurants, Heard Museum and Phoenix Art Museum. Enclosed backyard with a shared washer/dryer on property. The cottage has a queen bed, mini kitchen and private patio. Property is cleaned and sanitized according to the Airbnb cleaning procedures. 15 minutes from Sky Harbor Airport. 5 minutes from Encanto Park (Golf Course)

4.94 out of 5 average rating, 256 reviews

Guest suite in Encanto

Charming Guesthouse w/ Full Kitchen & Pool

You'll love your private stay in our charming space, centrally located in Phoenix's historic Melrose District. It's perfect for folks staying several days: powerful air conditioning, private laundry room, and access to a kitchen and our outdoor pool. You'll be a 10 minute drive from downtown Phoenix and a 15 minute drive from Sky Harbor Airport. With a private entrance and a dedicated covered parking spot, your stay couldn't be more convenient!

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Popular amenities for Osborn Medical Center, Phoenix holiday rentals

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Other great holiday rentals in Osborn Medical Center, Phoenix

Home in Coronado

4.73 out of 5 average rating, 468 reviews

Bohemian Getaway DOWNTOWN PHOENIX

JohnyRating, 5 stars2 weeks ago

This was a fantastic find! The space was spotless, comfortable, and had everything we needed. The host was incredibly polite and helpful needed, making our stay even better. My guest and I truly enjoyed this spot, and I will definitely be booking again and highly recommend!

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Home in Encanto

4.91 out of 5 average rating, 81 reviews

Charming Casita: Great for Long Stays & Top Hosts

PhilRating, 5 stars1 week ago

Back for a second stay -- a solid & reliable place for two. Nice hosts & in a central neighborhood with easy access to downtown (10 minutes away), neighborhood restaurants & other attractions. Would recommend.

4.99 out of 5 average rating, 323 reviews

Guest suite in Encanto

Private, desert-chic casita in vibrant Midtown PHX

ZoeRating, 5 stars3 weeks ago

The host, Jeremy, was outstanding. He was organized and replied fast, answering all our questions. My boyfriend had a bit of a medical emergency during our stay. Jeremy went above and beyond by giving us extra supplies to ensure he was comfortable and healing up. Beyond that, this place is super adorable, clean, comfortable, and has everything you might need. I could not recommend it enough.

4.97 out of 5 average rating, 90 reviews

Home in Willow

❤️of PHX • Heated Pool • Chef's Kitchen • Fast WiFi

EvelynRating, 5 stars1 month ago

Sean and Jessica were very responsive hosts to our requests and correctly directed us to the right place to look for the solutions, the neighborhood are quiet, convenient as well, we had a wonderful gathering during the stay, Thank you Sean and Jessica!

4.85 out of 5 average rating, 27 reviews

Adorable studio guest casita with free parking

NickRating, 5 stars2 months ago

Centrally located in a quiet residential area among offices so there was virtually no noise at night. The casita was private and spacious and exactly like the photos. Just a couple of minutes walk to the light rail/tram stop. The host was very communicative and pro active.

5 out of 5 average rating, 55 reviews

Home in Encanto

The PHX Bungalow CenPho retreat in the city!

WilliamRating, 5 stars1 month ago

This is the ultimate 5-star rental home. It's an ideal location walkable to restaurants, shops and bars, light rail, and includes easy parking. The home was squeaky clean and clutter-free with a well equipped kitchen as well as quality linens and towels. It includes historic features incorporated with modern upgrades and quality furnishings. The back yard was bigger than expected, great for morning coffee and evenings under the bistro lights. It includes a BBQ. It's a quiet and safe neighborhood. John was easy to communicate with. Highly Recommended!

4.99 out of 5 average rating, 94 reviews

Home in Encanto

Uptown Bungalow w/ Epic Backyard-Pet Friendly!

KimRating, 5 stars3 weeks ago

The house is amazing and the yard was perfect to sit outside and just relax. Everything was so beautiful and well done! The set up of the house and backyard was everything we needed! Great host and very helpful!