
Holiday rentals in Mule Key
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Top-rated holiday rentals in Mule Key
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Boat Slip - Waterfront Condo - Key West Pool
Be among the first to experience this spacious waterfront Key West getaway, newly available as a vacation rental! Enjoy a heated pool, marina views, an oversized private balcony, and over 1,200 sq ft of living space, all just minutes from Duval Street. Complete with a full kitchen, free parking, elevator access, pet-friendly accommodations, high-speed WiFi, and a private boat slip. Perfect for boating, fishing, beaches, and everything Key West has to offer. Pet friendly. 10-min from EYW airport.
5.0 out of 5 average rating, 11 reviews
The Sanchez House Room #2
There is no better welcome to Key West than staying in local and famous folk artist Mario Sanchez's birth home. This home was built in the 1860's in the heart of the historic Gato and Merrero cigar factory villages. Featuring original Dade County pine construction, and located right on historic Duval Street, the Sanchez House is guaranteed to offer the historic atmosphere and living a part of Key West many visitors want to experience. Sit on the balcony and enjoy the trade winds & Ocean Breeze.
4.85 out of 5 average rating, 711 reviews
Key West Outpost: eco-vacation
The Outpost is a unique experience. This is a place where you can be completely off the grid, but still have all of the amenities. Private conch cottage on the backcountry waters surrounding Key West. Enjoy watching the amazing wildlife from your private deck. You can paddle board, kayak or do some light tackle fishing right off the boat. You can even add eco-tours to enhance the adventure. We will take you out for arrival and bring you back on your departure day, via one of our other boats.
4.95 out of 5 average rating, 84 reviews
Gorgeous Ocean View in Paradise, Close to Key West
This is paradise! Wake up to a gentle breeze and birds singing just outside your balcony. Watch the sunrise over the ocean and mangroves from your private balcony. Enjoy your privacy as you start your day, then venture out to explore all that Key West has to offer: water sports, quaint shops, delicious food, history all around you, and so much more! On property features: Pool, Hot Tub, Yellowfin Bar & Kitchen and Parking. Beach supplies included: Coolers, Snorkel Gear and Beach Towels.
4.99 out of 5 average rating, 141 reviews
At Mine | Lovely Suite steps from Duval Street
Beautifully renovated boutique hotel suite steps from Duval Street. Located on a quiet street, it offers a private pool and peaceful stay for vacationers and business travelers. The unit includes a comfy Queen bed, mini fridge, microwave, iron & board, hangers, TV, and AC. Enjoy Key West's warm weather year-round. This special place is close to everything, making it easy to plan your trip. Just a heads-up: Key West’s famous roosters love to strut and crow—part of the island charm!
4.86 out of 5 average rating, 1744 reviews
The Lighthouse - Beach Houses Key West
If you’re reading this, you’re already one step closer to paradise. Thank you for considering us for your getaway. Our charming Lighthouse Bungalow is a 2-bedroom, 1-bath loft-style retreat located just steps from our private beach. The master bedroom loft, accessed by a spiral staircase, offers a stunning bird’s-eye view of the Atlantic Ocean. The nautical-inspired living area opens to an exterior deck overlooking the beach—an ideal spot for peaceful mornings and ocean breezes.
4.93 out of 5 average rating, 134 reviews
Santa Maria Suites, Two bedroom bi-level pool vie.
Step into the two bedroom luxury suite where elegant living spans two stories with a state of the art kitchen and in room washer and dryer unwind in the living room with two seating areas a queen pull out sleeper sofa and a 48 inch LED television upstairs bedrooms each feature a queen bed flat screen TV and large closets while bathrooms offer marble counters and lighted mirrors enjoy the view from your private balcony overlooking the pool and courtyard for a truly elevated stay.
4.9 out of 5 average rating, 41 reviews
Signature King at Beachside Resort
Set on seven acres of property overlooking the Gulf of Mexico, experience luxury at Beachside Resort & Residences. Unwind in the perfect blend of adventure and relaxation in sunny Key West. On property, you can find access to our resort pool, ocean marina, and the ability to book a sandbar or sunset cruise. Don’t miss out on fine dining at our award winning restaurant, Tavern N Town, or grab a delectable meal poolside at Chicken Walk.
4.62 out of 5 average rating, 359 reviews
Duval Corner - Pet friendly with Balcony
Welcome to Duval Corner! A beautifully updated one-bedroom condo in the heart of Downtown Key West. This second-floor retreat is perfect for travelers wanting to be steps from it all. Within walking distance to iconic attractions like the Southernmost Point, The Ernest Hemingway Home, and Mallory Square, plus dining hotspots such as Blue Heaven, 7 Fish, and Louie's Backyard; Duval Corner is the ideal base for your Key West adventure.
4.86 out of 5 average rating, 59 reviews
“The Easy Way” Comfy, Practical, Convenient
Reconnect with nature at this unforgettable escape. Stay off Key West away from the crowds and listen to nature. Vessel “Easy Way” is perfect for up to 2 people. Come enjoy the amazing sunrise and sunset. Cook out on the balcony, watch fish, birds, stingrays, and dolphins go by. Vessel Easy Way has an outdoor shower, paddle board, and outdoor grill. This floating home is perfect for people who want to relax and enjoy nature.
5.0 out of 5 average rating, 24 reviews
Tiki Suites ~ Original Tiki ~ Floating Bungalows
Stay on the water in this one-of-a-kind Tiki Suite in Key West. This private floating bungalow blends boat life with comfort, featuring a custom bed, panoramic views, and direct access to the ocean. Swim, paddle, or relax in a hammock surrounded by nature. A peaceful, off-grid glamping experience you won’t find anywhere else. Accessible by boat only.
4.91 out of 5 average rating, 562 reviews
Apartment in Key west
1 bedroom apartment in a duplex house. Separated spaces Private entrance Very large living room area with coffee bar included. Tv with Roku Activity’s for kids( coloring pages, games & more) Newly renovated bathroom as well as the living room. Hot plate, full size fridge, microwave & pots and pans. NO SMOKING INSIDE.
4.8 out of 5 average rating, 5 reviewsPopular amenities for Mule Key holiday rentals
Other great holiday rentals in Mule Key

Ridley House - Key West Historic Inns, Premium ki.
5.0 out of 5 average rating, 7 reviews
Parrot Key Hotel & Villas, Selected by hotel
4.76 out of 5 average rating, 111 reviews
Ella's Cottages - Key West Historic Inns, King ci.
4.96 out of 5 average rating, 28 reviews
Lighthouse Hotel - Key West Historic Inns, 1 Queen
4.85 out of 5 average rating, 13 reviews
*Near Mallory Square | Resort Pool, Dining + Bar
4.68 out of 5 average rating, 31 reviews
H2O Suites, Deluxe luxury suite private pool
4.71 out of 5 average rating, 7 reviews
Havana Cabana at Key West, Havana king room
5.0 out of 5 average rating, 5 reviews
Fitch Lodge- Key West Historic Inns, King room
4.6 out of 5 average rating, 63 reviewsDestinations to explore
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- Sombrero Beach
- Smathers Beach
- Bahia Honda State Park
- Ernest Hemingway Home & Museum
- Seven Mile Bridge
- Fort Zachary Taylor Historic State Park
- Southernmost Point
- Key West Butterfly & Nature Conservatory
- Key West Lighthouse Museum
- Boca Grande Key
- Mel Fisher Maritime Museum
- Truman Little White House
- Key West Aquarium





