
House holiday rentals in Mira Mesa, San Diego
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Top-rated house rentals in Mira Mesa, San Diego
Guests agree: these houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for house rentals in Mira Mesa, San Diego
House rentals with a pool

3 BR Urban Oasis with Pool and Spa in Great Area

Southern California Luxury in Quiet Neighborhood

Fletcher Hills luxury, Sunset View, 4 BR, Pool/Spa

Family Friendly Retreat:Game Room/Pool/Hot Tub/BBQ

Kids Paradise San Diego - Funhouse

Bright and spacious home with views, pool & spa.

Secluded Resort View Home. Salt Water Pool & Spa.

University Heights Oasis Getaway
Weekly house rentals

Home in San Diego

Charming Family 3BR w/ Game Room

Cabin in the woods- self check in- free standing

Close to Everything San Diego | Firepit + Office!

Urban Oasis - Just Remodeled

Ventana Vista | Ocean View | EV Charger | Designer

Game Room! Patio, Grill, Backyard, Family-Friendly

Bright Cozy 3b/2b with nice backyard & BBQ
Private house rentals

Charming Coastal Cottage- close to beach/ downtown

2 private masters, new beds & furniture, sleeps 12

Shadow House Mt. Helix

Serenity Poolside Villa | Central | Private Pool

Welcome to Casa Cortina!

Peace in Penasquitos

Traveler's Dream New Modern Farmhouse Getaway

20% OFF- Newly updated guesthome for families
Quick stats about house rentals in Mira Mesa, San Diego
Total rentals
210 properties
Total number of reviews
9.5K reviews
Family-friendly rentals
70 properties are a good fit for families
Pet-friendly rentals
30 properties allow pets
Rentals with a pool
20 properties have a pool
Rentals with dedicated workspaces
140 properties have a dedicated workspace
Destinations to explore
- Rentals with a firepit Mira Mesa
- Fitness-friendly rentals Mira Mesa
- Rentals with pools Mira Mesa
- Family-friendly rentals Mira Mesa
- Rentals with a washing machine and dryer Mira Mesa
- Rentals with a fireplace Mira Mesa
- Flat rentals Mira Mesa
- Rentals with outdoor seating Mira Mesa
- Rentals with a hot tub Mira Mesa
- Family-friendly rentals Mira Mesa
- Rentals with a beach view Mira Mesa
- Private suite rentals Mira Mesa
- Pet-friendly rentals Mira Mesa
- Rentals with a patio Mira Mesa
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